APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1.

Autor: Sarkar S; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Morris J; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., You Y; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Sexmith H; Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, USA., Street SE; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA., Thibert SM; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Attah IK; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Hutchinson Bunch CM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Novikova IV; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Evans JE; Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, WA, USA., Shah AS; Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, USA., Gordon SM; Department of Physiology and the Saha Cardiovascular Research Center, University of Kentucky College of Medicine, Lexington, KY, USA., Segrest JP; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Bornfeldt KE; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Vaisar T; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Heinecke JW; Department of Medicine, UW Medicine Diabetes Institute, University of Washington, Seattle WA, USA., Davidson WS; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: sean.davidson@uc.edu., Melchior JT; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA; Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, OH, USA; Department of Neurology, Oregon Health and Science University, Portland, OR, USA. Electronic address: john.melchior@pnnl.gov.

Publikováno v: Journal of lipid research [J Lipid Res] 2024 Dec; Vol. 65 (12), pp. 100686. Date of Electronic Publication: 2024 Oct 28.