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pro vyhledávání: '"Hutchinson, John H."'
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Autor:
Stebbins, Karin J., Broadhead, Alex R., Correa, Lucia D., Scott, Jill M., Truong, Yen P., Stearns, Brian A., Hutchinson, John H., Prasit, Peppi, Evans, Jilly F., Lorrain, Daniel S.
Publikováno v:
In European Journal of Pharmacology 2010 638(1):142-149
Autor:
Lorrain, Daniel S., Bain, Gretchen, Correa, Lucia D., Chapman, Charles, Broadhead, Alex R., Santini, Angelina M., Prodanovich, Patricia P., Darlington, Janice V., Stock, Nicholas S., Zunic, Jasmine, King, Christopher D., Lee, Catherine, Baccei, Christopher S., Stearns, Brian, Roppe, Jeffrey, Hutchinson, John H., Prasit, Peppi, Evans, Jilly F.
Publikováno v:
In European Journal of Pharmacology 2010 640(1):211-218
Autor:
MacKenna, Deidre A, Rowbottom, Martin W., Shannon, Kristen E., Ma, Gina L., Nguyen, Katherine, Darlington, Janice, Calderon, Imelda, King, Christopher D., Hutchinson, John H., Evans, Jilly F., Bain, Gretchen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed8fbef815c4b391f20a1fe1ce17fe5d
Autor:
Evans, Jilly F.1 jilly.evans@amirapharm.com, Hutchinson, John H.1
Publikováno v:
Nature Chemical Biology. Jul2010, Vol. 6 Issue 7, p476-479. 4p. 3 Diagrams, 1 Chart.
Autor:
Frenette, Richard, Hutchinson, John H., Léger, Serge, Thérien, Michel, Brideau, Christine, Chan, Chi C., Charleson, Stella, Ethier, Diane, Guay, Jocelyne, Jones, Tom R., McAuliffe, Malia, Piechuta, Hanna, Riendeau, Denis, Tagari, Philip, Girard, Yves
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(16):2391-2396
Autor:
HUTCHINSON, JOHN H., DOODY, JAMES J.
Publikováno v:
The Military Engineer, 1971 Mar 01. 63(412), 105-107.
Externí odkaz:
https://www.jstor.org/stable/44565819
Autor:
Charles Chapman, Alex R. Broadhead, Peppi Prasit, Christopher Baccei, Nicholas Simon Stock, Yiwei Li, Jeffrey Roger Roppe, Angelina M. Santini, Dan Lorrain, Lucia Correa, Gretchen Bain, Jasmine Eleanor Zunic, Jeannie Ziff, Christopher D. King, Catherine Lee, Pat Prodanovich, Janice Darlington, Haojing Rong, Jilly F. Evans, Hutchinson John H
Publikováno v:
Journal of Medicinal Chemistry. 54:8013-8029
The potent 5-lipoxygenase-activating protein (FLAP) inhibitor 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid 11cc is described (AM803, now GSK2190915). Building upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbf179f44ba2592906663a125ace36d
https://doi.org/10.1021/jm2008369
https://doi.org/10.1021/jm2008369
Autor:
Christopher Baccei, Jilly F. Evans, Daniel S. Lorrain, Yen Troung, Hutchinson John H, Peppi Prasit, Janice Darlington, Gretchen Bain, Brian Andrew Stearns, Christopher D. King, Catherine Lee, Karin J. Stebbins, Alex R. Broadhead, Angelina M. Santini, Pat Prodanovich
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 338:290-301
The prostaglandin D(2) (PGD(2)) receptor type 2 (DP2) is a G protein-coupled receptor that has been shown to be involved in a variety of allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis. In this study, we describe the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6712b393e7da1ebfb64225ffc12e7bfe
https://doi.org/10.1124/jpet.111.180430
https://doi.org/10.1124/jpet.111.180430
Autor:
Timothy Parr, Jeffrey Roger Roppe, Christopher Baccei, Gretchen Bain, Janice Darlington, Nicholas Simon Stock, Charles Chapman, Lucia Correa, Alex R. Broadhead, Hutchinson John H, Daniel S. Lorrain, Brian Andrew Stearns, Christopher D. King, Angelina M. Santini, Catherine Lee, Karin J. Stebbins, Pat Prodanovich, Peppi Prasit, Jilly F. Evans, Deborah Volkots
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:1036-1040
Compound 21 (AM432) was identified as a potent and selective antagonist of the DP2 receptor (CRTH2). Modification of a bi-aryl core identified a series of tri-aryl antagonists of which compound 21 proved a viable clinical candidate. AM432 shows excel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61da34684106e4141e51f6fe39171d6
https://doi.org/10.1016/j.bmcl.2010.12.016
https://doi.org/10.1016/j.bmcl.2010.12.016