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of 111
pro vyhledávání: '"Huston WM"'
The human cervicovaginal microbiome has an important role in the health and homoeostasis of the female reproductive tract. A eubiotic microbiome is typically dominated with lactic acid producing bacteria and is categorised into five community state t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::240d8138c67a1b535cec3480ea5f0e30
https://hdl.handle.net/10453/152296
https://hdl.handle.net/10453/152296
Dual RNA-seq experiments examining viral and bacterial pathogens are increasing, but vary considerably in their experimental designs, such as infection rates and RNA depletion methods. Here, we have applied dual RNA-seq to Chlamydia trachomatis infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::17fe4e27d1b262f71eeee808a0a81a82
https://hdl.handle.net/10453/143872
https://hdl.handle.net/10453/143872
Chlamydia are Gram-negative, obligate intracellular bacterial pathogens responsible for a broad spectrum of human and animal diseases. In humans, Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection worldwide and is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::0b2b8c59925e82655e055efea042efec
https://hdl.handle.net/10453/143846
https://hdl.handle.net/10453/143846
Autor:
Luo, Z, Neville, SL, Campbell, R, Morey, JR, Menon, S, Thomas, M, Eijkelkamp, BA, Ween, MP, Huston, WM, Kobe, B, McDevittd, CA
Copyright © 2019 American Society for Microbiology. All Rights Reserved. The obligate intracellular pathogen Chlamydia trachomatis is a globally significant cause of sexually transmitted bacterial infections and the leading etiological agent of prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::80dda60183100601dd90b54741065b4d
https://hdl.handle.net/10453/137248
https://hdl.handle.net/10453/137248
© 2019 The Author(s). Background: Chlamydia trachomatis infections in women continue to be a major public health concern due to their high prevalence and consequent reproductive morbidities. While antibiotics are usually efficient to clear the Chlam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e38f13c453fd0b58592541cecc0bbfa7
https://hdl.handle.net/10453/132075
https://hdl.handle.net/10453/132075
Autor:
Phillips, S, Vodstrcil, LA, Huston, WM, Lawerence, A, Timms, P, Chen, MY, Worthington, K, McIver, R, Bradshaw, CS, Garland, SM, Tabrizi, SN, Hocking, JS
© 2018, Springer-Verlag GmbH Germany, part of Springer Nature. Spontaneous resolution of urogenital Chlamydia trachomatis (CT) without treatment has previously been described, but a limitation of these reports is that DNA or RNA-based amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ba16e4afbbcf9e9a1670782ec1ade0bd
https://hdl.handle.net/10453/127282
https://hdl.handle.net/10453/127282
© FEMS 2015. All rights reserved. Chlamydia trachomatis infections can result in the development of serious sequelae such as pelvic inflammatory disease and tubal infertility. In this study, peripheral blood mononuclear cells from women who were und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b2f66f5026c55f12d5fd1a7669e7eeaa
https://hdl.handle.net/10453/41115
https://hdl.handle.net/10453/41115
Autor:
Menon, S, Stansfield, SH, Logan, B, Hocking, JS, Timms, P, Rombauts, L, Allan, JA, Huston, WM
© 2016 The Authors. Chlamydia trachomatis results in tubal factor infertility in some women. Diagnosis of this tubal infertility is difficult and typically involves laparoscopy or hysterosalpingography to detect the tubal blockages. Numerous serolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::c3cb4ebe21e1de883a2c0ec3f6a52232
https://hdl.handle.net/10453/48273
https://hdl.handle.net/10453/48273
Autor:
Zhu, Y, Pham, TH, Nhiep, THN, Vu, NMT, Marcellin, E, Chakrabortti, A, Wang, Y, Waanders, J, Lo, R, Huston, WM, Bansal, N, Nielsen, LK, Liang, ZX, Turner, MS
© 2016 John Wiley & Sons Ltd. The second messenger cyclic-di-adenosine monophosphate (c-di-AMP) plays important roles in growth, virulence, cell wall homeostasis, potassium transport and affects resistance to antibiotics, heat and osmotic stress. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::8d8c9344887bd738dad123ad80baf87d
https://hdl.handle.net/10453/41116
https://hdl.handle.net/10453/41116
Autor:
Ong, VA, Lawrence, A, Timms, P, Vodstrcil, LA, Tabrizi, SN, Beagley, KW, Allan, JA, Hocking, JS, Huston, WM
© 2015 Institut Pasteur. The present study aimed to establish if a previously identified Chlamydia trachomatis HtrA (CtHtrA) inhibitor, JO146, is effective against currently circulating clinical isolates to validate if CtHtrA is a clinically relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::74c44564dc0365212f349ebc25e6d509
https://hdl.handle.net/10453/41117
https://hdl.handle.net/10453/41117