Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hussin A Rothan"'
Autor:
Hussin A Rothan, Hirbod Bahrani, Zulqarnain Mohamed, Teow Chong Teoh, Esaki M Shankar, Noorsaadah A Rahman, Rohana Yusof
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126360 (2015)
Lack of vaccine and effective antiviral drugs against chikungunya virus (CHIKV) outbreaks have led to significant impact on health care in the developing world. Here, we evaluated the antiviral effects of tetracycline (TETRA) derivatives and other co
Externí odkaz:
https://doaj.org/article/6384f8424c924536a9335969cfd74b65
Autor:
Hussin A Rothan, Jamunaa Ambikabothy, Ammar Y Abdulrahman, Hirbod Bahrani, Mojtaba Golpich, Elham Amini, Noorsaadah A Rahman, Teow Chong Teoh, Zulqarnain Mohamed, Rohana Yusof
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139248 (2015)
The production of short anticancer peptides in recombinant form is an alternative method for costly chemical manufacturing. However, the limitations of host toxicity, bioactivity and column purification have impaired production in mass quantities. In
Externí odkaz:
https://doaj.org/article/30fdafd23d41487987b4ad48d4e41a43
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94561 (2014)
Dengue virus (DENV) broadly disseminates in tropical and sub-tropical countries and there are no vaccine or anti-dengue drugs available. DENV outbreaks cause serious economic burden due to infection complications that requires special medical care an
Externí odkaz:
https://doaj.org/article/22b7a6d83b9b4f08b16712fc9cbdeaae
Autor:
Hussin A. Rothan, Pratima Kumari, Shannon Stone, Janhavi P. Natekar, Komal Arora, Tabassum T. Auroni, Mukesh Kumar
Publikováno v:
Pathogens, Vol 11, Iss 2, p 257 (2022)
Transgenic mice expressing human angiotensin-converting enzyme 2 under the cytokeratin 18 promoter (K18-hACE2) have been extensively used to investigate the pathogenesis and tissue tropism of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
Externí odkaz:
https://doaj.org/article/3ec25e81495b4951859f4dc2471aea2f
Publikováno v:
Pathogens, Vol 9, Iss 7, p 538 (2020)
In the absence of therapeutic interventions, and a possible vaccine candidate, the spread of COVID-19 disease and associated fatalities are on the rise. The high mutation frequency in the genomic material of these viruses supports their ability to ad
Externí odkaz:
https://doaj.org/article/cd02ef1ac0044965ac1fd47eca81ab94
Autor:
Wisam Al-Faqheri, Fatimah Ibrahim, Tzer Hwai Gilbert Thio, Norulain Bahari, Hamzah Arof, Hussin A. Rothan, Rohana Yusof, Marc Madou
Publikováno v:
Sensors, Vol 15, Iss 3, Pp 4658-4676 (2015)
In this paper, we propose an easy-to-implement passive liquid valve (PLV) for the microfluidic compact-disc (CD). This valve can be implemented by introducing venting chambers to control the air flow of the source and destination chambers. The PLV me
Externí odkaz:
https://doaj.org/article/dc577c6ab0bf4eab8249b5c99cffc3cf
Autor:
Hussin A. Rothan, Mukesh Kumar
Publikováno v:
Pathogens, Vol 8, Iss 3, p 148 (2019)
Flavivirus replication in host cells requires the formation of replication and assembly complexes on the cytoplasmic side of the endoplasmic reticulum (ER) membrane. These complexes consist of an ER membrane, viral proteins, and host proteins. Genome
Externí odkaz:
https://doaj.org/article/441a9b4719d24e52b5f041f76ea9ca80
Autor:
Janhavi Prasad Natekar, Heather Pathak, Shannon Stone, Pratima Kumari, Shaligram Sharma, Komal Arora, Hussin Alwan Rothan, Mukesh Kumar
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic resulting in millions of deaths worldwide. Increasingly contagious variants of concern (VoC) have fueled recurring global infection waves. A major question is the rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3b6b5ea9231f54528313153dd7e5bf
https://doi.org/10.1101/2022.04.04.486975
https://doi.org/10.1101/2022.04.04.486975
Autor:
Devendra K. Rai, Irina Yurgelonis, Patricia McMonagle, Hussin A. Rothan, Li Hao, Alexey Gribenko, Elizabeth Titova, Barry Kreiswirth, Kris M. White, Yuao Zhu, Annaliesa S. Anderson, Rhonda D. Cardin
New variants of SARS-CoV-2 with potential for enhanced transmission, replication, and immune evasion capabilities continue to emerge causing reduced vaccine efficacy and/or treatment failure. As of January 2021, the WHO has defined five ‘variants o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6557b035c3b9b34b6201cb2abe524c10
https://doi.org/10.1101/2022.01.17.476644
https://doi.org/10.1101/2022.01.17.476644
Autor:
Shengyun Fang, Mark J. Henderson, Feihu Chen, Yongwang Zhong, Wenjing Yan, Jingjing Ruan, Hussin A. Rothan
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Infection with flaviviruses, such as dengue virus (DENV) and the recently re-emerging Zika virus (ZIKV), represents an increasing global risk. Targeting essential host elements required for flavivirus replication represents an attractive approach for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a393ad4826fe317ea3e1250aa28589
http://link.springer.com/article/10.1038/s41598-019-47532-7
http://link.springer.com/article/10.1038/s41598-019-47532-7