Zobrazeno 1 - 10
of 907
pro vyhledávání: '"Husseini K. Manji"'
Autor:
Rodrigo Machado-Vieira, Alan C. Courtes, Carlos A. Zarate, Ioline D. Henter, Husseini K. Manji
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Bipolar disorder (BD) is characterized by extreme mood swings ranging from manic/hypomanic to depressive episodes. The severity, duration, and frequency of these episodes can vary widely between individuals, significantly impacting quality of life. I
Externí odkaz:
https://doaj.org/article/b569933ff9f3420c8d6a8ca889b71250
Publikováno v:
Communicative & Integrative Biology, Vol 2, Iss 4, Pp 350-352 (2009)
It has become increasingly clear that glucocorticoid (GC) signaling not only comprises classic nuclear receptor binding—that is, glucocorticoid receptors (GRs) to their response element in the nucleus—but also involves rapid, non-genomic efforts
Externí odkaz:
https://doaj.org/article/cf38a3e25e8f436daa79c39b8eab14bd
Autor:
Pilar Lim, Husseini K. Manji, Rosanne Lane, Ella Daly, Wayne C. Drevets, Rachel Ochs-Ross, Carol Jamieson, David C. Steffens, Yun Zhang, Jaskaran Singh, David Hough, Gerard Sanacora, Ewa Wajs
Publikováno v:
The American Journal of Geriatric Psychiatry. 30:541-556
Background Older, compared with younger, patients with treatment-resistant depression (TRD) typically have lower response and remission rates with poorer tolerability to antidepressant treatment. This post-hoc analysis compared outcomes following tre
Autor:
Marion Leboyer, Charles F. Reynolds, Erin Smith, Ioannis Tarnanas, Ernestine Fu, Julio Licinio, Chee H. Ng, Dilip V. Jeste, Sarah Caddick, Sandra B. Chapman, Michael Berk, Zoe Wainer, Harris A. Eyre, Husseini K. Manji, William Hynes, Ian H. Robertson, Eric A. Storch, Howard Fillit, Rhoda Au, Ryan Abbott, Jair C. Soares, Andrew W. Lo, Agustín Ibáñez, Gowri Aragam, Walter D. Dawson, Diab Ali, Facundo Manes, Patrick Brannelly, Helen Lavretsky, Cara M. Altimus, Jeffrey L. Cummings, Bill Wilkerson, Kunmi Sobowale
Publikováno v:
Molecular psychiatry, vol 26, iss 1
Mol Psychiatry
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Mol Psychiatry
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The time is now to catalyze a Grand Strategy. Brain Capital can be a key component in shaping economic resilience?linked to our digitalized, globalized, complex, and interconnected yet fragile global economy. Brain Capital resonates with existing eff
Autor:
Shaolei Luo, Bruce S. McEwen, Yangyang Hou, Peixiong Yuan, Yue Jia, Husseini K. Manji, Lei Feng, Yaping Zhang, Richard G. Hunter, Haoran Li, Chunjie Xiao, Hongkun Bao, Gang Wang, Jing Du
Publikováno v:
Journal of Neurochemistry. 158:358-372
Molecular abnormalities within the Glucocorticoid Receptor (GR) stress signaling pathway involved in dysfunction of mitochondria and confer vulnerability to stress related psychiatric disorders. Bcl-2 associated athanogene (Bag-1) is a target for the
Autor:
Rosanne Lane, Wayne C. Drevets, Xin Qiu, Dong-Jing Fu, Siegfried Kasper, Dawn F. Ionescu, Carla M. Canuso, Pilar Lim, David Hough, Husseini K. Manji
Publikováno v:
International Journal of Neuropsychopharmacology
BackgroundPatients with major depressive disorder (MDD) having active suicidal ideation with intent require immediate treatment.MethodsThis double-blind study (ASPIRE II) randomized adults (aged 18–64 years) with MDD having active suicidal ideation
Autor:
Bray Patrick-Lake, Roberto A. Calle, Husseini K. Manji, Diane Stephenson, John A. Wagner, Peter Honig, Pat Furlong, Bruce J. Tromberg, Vadim Zipunnikov, Matthew Hotopf, Vaibhav A. Narayan, Qi Liu, Andrea Bell-Vlasov, Pam Tenaerts, Robert J. Mather, Francesca Cerreta, Ieuan Clay, Rob Goldel, Steven C. Hoffmann, Jennifer S. Goldsack, Amos Folarin, Ninad Amondikar, Jill Heemskerk, Nadir Ammour, Joseph P. Menetski, Luca Foschini, Srikanth Vasudevan, Elektra J. Papadopoulos, Tania Nayak Kamphaus, Steven Berman, Bakul Patel, Elena S. Izmailova, Peter M.A. Groenen, Christopher Leptak, Laurent Servais, Linda S. Brady, Dan Bloomfield, Abhishek Pratap, Jagdeep T. Podichetty, Xuemei Cai, Michelle Campbell, Steve Usdin, Daniel R. Karlin
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 94-101 (2021)
Clinical and Translational Science
Clinical and Translational Science
The use of digital health products has gained considerable interest as a new way to improve therapeutic research and development. Although these products are being adopted by various industries and stakeholders, their incorporation in clinical trials
Autor:
Husseini K. Manji, Vanessa Candeias, Nitish V. Thakor, Andrew E. Welchman, Simon Tottman, I-han Chou, Helen Herrman, Sir Philip Campbell, Shekhar Saxena, Kim Hei-Man Chow, Barbara Harvey, P. Murali Doraiswamy, Bjarte Reve, Caroline Montojo, Tan Le, Peter Varnum, Karen S. Rommelfanger, Mohammad Abdul Aziz Sultan Al Olama, Alvaro Fernández Ibáñez, Sung-Jin Jeong, Charlotte Stix, Elisha London
Publikováno v:
NAM Perspect
Autor:
Rym Ayadi, Retsina Meyer, Sandra B. Chapman, William L. Ellsworth, Facundo Manes, William Hynes, Naoko Kawaguchi, Zoltán Sarnyai, Agustín Ibáñez, Walter D. Dawson, Gowri Aragam, Harris A. Eyre, Michael A. Freeman, Benjamin F. Miller, Patrick Brannelly, Erin Smith, Carol Graham, Eric A. Storch, Michael Berk, Husseini K. Manji, Marion Leboyer, Jeffrey L. Cummings, Cara M. Altimus
Publikováno v:
Neuron
Brains are indispensable drivers of human progress. Why not invest more heavily in them? We seek to place Brain Capital at the center of a new narrative to fuel economic and societal recovery and resilience.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4fc6eb68dfc3b6a55cf23193e212b6
https://europepmc.org/articles/PMC8240507/
https://europepmc.org/articles/PMC8240507/
Publikováno v:
The Lancet. Psychiatry