Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Hussein N, Yassine"'
Autor:
Cristiana J. Meuret, Yueming Hu, Sabrina Smadi, Mikaila Ann Bantugan, Haotian Xian, Ashley E. Martinez, Ronald M. Krauss, Qiu-Lan Ma, Dobrin Nedelkov, Hussein N. Yassine
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Carrying the apolipoprotein E (ApoE) Ɛ4 allele is associated with an increased risk of cerebral amyloidosis and late-onset Alzheimer’s disease, but the degree to which apoE glycosylation affects its development is not clear. In a previous
Externí odkaz:
https://doaj.org/article/3c307bb5587b4dba8f954cc7b7f205ad
Autor:
Brandon Ebright, Isaac Assante, Roy A. Poblete, Shaowei Wang, Marlon V. Duro, David A. Bennett, Zoe Arvanitakis, Stan G. Louie, Hussein N. Yassine
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Chronic neuroinflammation is one of the hallmarks of late-onset Alzheimer’s disease (AD) dementia pathogenesis. Carrying the apolipoprotein ε4 (APOE4) allele has been associated with an accentuated response to brain inflammatio
Externí odkaz:
https://doaj.org/article/ce38da9f358f4c649be9cec68b9ff117
Autor:
Mikaila Ann Bantugan, Haotian Xian, Victoria Solomon, Mitchell Lee, Zhiheng Cai, Shaowei Wang, Marlon V. Duro, Bilal E. Kerman, Alfred Fonteh, Cristiana Meuret, Meitong Li, Meredith N. Braskie, Laura Beth J. McIntire, Lucia Jurin, Sarah Oberlin, James Evans, Roderick Davis, Wendy J. Mack, Laila Abdullah, Hussein N. Yassine
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100354- (2023)
Apolipoprotein ε allele 4 (APOE4) influences the metabolism of polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acid (DHA). The entorhinal cortex (EC) in the brain is affected early in Alzheimer's disease and is rich in DHA. The purpose o
Externí odkaz:
https://doaj.org/article/4818e403911f4ab78437563831b4fb47
Autor:
Sasan D. Noveir, Bilal E. Kerman, Haotian Xian, Cristiana Meuret, Sabrina Smadi, Ashley E. Martinez, Johannes Johansson, Henrik Zetterberg, Bryan A. Parks, Zsuzsanna Kuklenyik, Wendy J. Mack, Jan O. Johansson, Hussein N. Yassine
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Inducing brain ATP-binding cassette 1 (ABCA1) activity in Alzheimer’s disease (AD) mouse models is associated with improvement in AD pathology. The purpose of this study was to investigate the effects of the ABCA1 agonist peptid
Externí odkaz:
https://doaj.org/article/fc227b3fd34d459286120dcf7494e388
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Patrick M. Sullivan, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-21 (2022)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/9b6fcfbf82ae45668070da91de7eda75
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
The APOE ε2, ε3, and ε4 alleles differentially impact various complex diseases and traits. We examined whether these alleles modulated associations of 94 single-nucleotide polymorphisms (SNPs) harbored by 26 genes in 19q13.3 region with 217 plasma
Externí odkaz:
https://doaj.org/article/d9da6cdfd31e4a59a52ac8077b1b005f
Autor:
Shaowei Wang, Boyang Li, Victoria Solomon, Alfred Fonteh, Stanley I. Rapoport, David A. Bennett, Zoe Arvanitakis, Helena C. Chui, Carol Miller, Patrick M. Sullivan, Hoau-Yan Wang, Hussein N. Yassine
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calciu
Externí odkaz:
https://doaj.org/article/754e453573674c8fbaddf6c526d4ec90
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/b1ae0ff0b5b64d5b968a8ba69268bafa
Autor:
Juno Van Valkenburgh, Cristiana Meuret, Ashley E. Martinez, Vibha Kodancha, Victoria Solomon, Kai Chen, Hussein N. Yassine
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
High-density lipoproteins (HDLs) are complex, heterogenous lipoprotein particles, consisting of a large family of apolipoproteins, formed in subspecies of distinct shapes, sizes, and functions and are synthesized in both the brain and the periphery.
Externí odkaz:
https://doaj.org/article/702b9737545b4386a0b41778dd0fb15f
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100014- (2021)
Apolipoproteins C-I, C-II, and C-III interact with ApoE to regulate lipoprotein metabolism and contribute to Alzheimer's disease pathophysiology. In plasma, apoC-I and C-II exist as truncated isoforms, while apoC-III exhibits multiple glycoforms. Thi
Externí odkaz:
https://doaj.org/article/7d2d667d0df94ffb83ee3566495ba47b