Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hussein G. Ibrahim"'
Publikováno v:
Journal of Applied Polymer Science. 127:4138-4149
The work aims at developing a CR formulation, with high encapsulation efficiency of diltiazem HCl, suitable for twice daily administration. Microparticles, using EVA copolymer, were prepared by coacervation-phase separation technique, subjected to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0e9afb20948128b07062f274c7072d
https://doi.org/10.1002/app.38013
https://doi.org/10.1002/app.38013
Publikováno v:
International Journal of Pharmaceutics. 212:73-80
Release of salicylic acid, diclofenac acid, diclofenac diethylamine and diclofenac sodium, from lyotropic structured systems, namely; neat and middle liquid crystalline phases, across mid-dorsal hairless rat skin into aqueous buffer were studied. Rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03a51eb894a7754ead356108aba66fc
https://doi.org/10.1016/s0378-5173(00)00585-8
https://doi.org/10.1016/s0378-5173(00)00585-8
Autor:
Hussein G. Ibrahim, E. Sallam
Publikováno v:
International Journal of Pharmaceutics. 93:111-120
The dissolution process from a disintegrating tablet was treated mathematically so that separate contributions to dissolution from granules and primary drug particles were taken into account in a new dissolution model. Two equations were derived whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf9f5bcb07a7a8c56739a9f894d1e4a
https://doi.org/10.1016/0378-5173(93)90169-g
https://doi.org/10.1016/0378-5173(93)90169-g
Publikováno v:
Pharmaceutical Research. 10:737-742
We investigated the effects of increased concentrations of the solutes, salicylic acid, benzoic acid, and o-, m-, and p-methoxy benzoic acids, on the anisotropic properties of a liquid crystal solvent. The lamellar liquid crystal was composed of 37%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d3023f0e9a4a126044b9a84c369bf9
https://doi.org/10.1023/a:1018920118631
https://doi.org/10.1023/a:1018920118631
Publikováno v:
International Journal of Pharmaceutics. 67:247-257
Excipient particles having highly indented surfaces such as Emcompress powder, entrapped drug particles and/or agglomerates, thus hindering their dispersion into the powder mixture and reduced the surface area available for dissolution. The result wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3106a929c8b23e42837303a6af2af292
https://doi.org/10.1016/0378-5173(91)90207-5
https://doi.org/10.1016/0378-5173(91)90207-5
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 54(1)
In this investigation, modified-release dosage forms of diltiazem HCl (DT) and diclofenac sodium (DS) were prepared. The development work comprised two main parts: (a) loading the drug into ethylene vinyl acetate (EVA) polymer, and (b) generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec7b0fa135993c5ae9e486ea111ea3f
https://pubmed.ncbi.nlm.nih.gov/12084505
https://pubmed.ncbi.nlm.nih.gov/12084505
Publikováno v:
Drug Development and Industrial Pharmacy. 14:1249-1276
Interactive mixtures of fine cohesive drug powders and coarse free flowing excipients are reported to increase dissolution rates of poorly soluble drugs. However, dissolution rates are known to be affected by the solubility characteristics of the exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50763cfca539b6c9e289229e1899fd0
https://doi.org/10.3109/03639048809151932
https://doi.org/10.3109/03639048809151932
Publikováno v:
Drug Development and Industrial Pharmacy. 14:1277-1302
The efficiency of interactive powder mixtures as a process used to increase the dissolution rate of poorly soluble drugs is dependent on the degree and extent of dispersion of drug agglomerates into individual particles. Furthermore, the dispersion m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d0a0beeae0631c054cfa83c0d56c646
https://doi.org/10.3109/03639048809151933
https://doi.org/10.3109/03639048809151933
Autor:
Hussein G. Ibrahim, Edward G. Rippie
Publikováno v:
Journal of pharmaceutical sciences. 65(11)
The microenvironmental orientation effects, arising from an orderer solvent structure, were studied in a model liquid crystalline biophase for the cyclization of a series of 2-substituted cyclohexanone phenylhydrazones. The magnitude of such solvent-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fc4c846076347337dda89c2bace080
https://pubmed.ncbi.nlm.nih.gov/993997
https://pubmed.ncbi.nlm.nih.gov/993997
Autor:
Hussein G. Ibrahim
Publikováno v:
Journal of pharmaceutical sciences. 74(5)
Two test drugs, hydrochlorothiazide and phenylbutazone, were separately incorporated into a standard formulation to study their disintegration and dissolution properties as a function of compression force. The increase in dissolution with force was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03ec81756a7c0930bd7cf6117966767
https://pubmed.ncbi.nlm.nih.gov/4020638
https://pubmed.ncbi.nlm.nih.gov/4020638