Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Hussein Akel"'
1
Akademický článek
Expanding Quality by Design Principles to Support 3D Printed Medical Device Development Following the Renewed Regulatory Framework in Europe
Autor: Livia Adalbert, S P Yamini Kanti, Orsolya Jójárt-Laczkovich, Hussein Akel, Ildikó Csóka
Publikováno v: Biomedicines, Vol 10, Iss 11, p 2947 (2022)
The vast scope of 3D printing has ignited the production of tailored medical device (MD) development and catalyzed a paradigm shift in the health-care industry, particularly following the COVID pandemic. This review aims to provide an update on the c
Externí odkaz: https://doaj.org/article/eb9b8ba9f2b747f6a9cb49b71daf8750
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2
Akademický článek
Quality-by-Design-Based Development of n-Propyl-Gallate-Loaded Hyaluronic-Acid-Coated Liposomes for Intranasal Administration
Autor: Fakhara Sabir, Gábor Katona, Edina Pallagi, Dorina Gabriella Dobó, Hussein Akel, Dániel Berkesi, Zoltán Kónya, Ildikó Csóka
Publikováno v: Molecules, Vol 26, Iss 5, p 1429 (2021)
The present study aimed to develop n-propyl gallate (PG)-encapsulated liposomes through a novel direct pouring method using the quality-by-design (QbD) approach. A further aim was to coat liposomes with hyaluronic acid (HA) to improve the stability o
Externí odkaz: https://doaj.org/article/937c87dfec5f4627b87bf1120a5d0596
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4
In Vitro Comparative Study of Solid Lipid and PLGA Nanoparticles Designed to Facilitate Nose-to-Brain Delivery of Insulin
Autor: Hussein Akel, Ildikó Csóka, Rita Ambrus, Alexandra Bocsik, Ilona Gróf, Mária Mészáros, Anikó Szecskó, Gábor Kozma, Szilvia Veszelka, Mária A. Deli, Zoltán Kónya, Gábor Katona
Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13258
International Journal of Molecular Sciences, Vol 22, Iss 13258, p 13258 (2021)
International Journal of Molecular Sciences
The brain insulin metabolism alteration has been addressed as a pathophysiological factor underlying Alzheimer’s disease (AD). Insulin can be beneficial in AD, but its macro-polypeptide nature negatively influences the chances of reaching the brain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04af6cee7c70bae10a7a6766c0a0c0a
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5
Quality-by-Design-Based Development of n-Propyl-Gallate-Loaded Hyaluronic-Acid-Coated Liposomes for Intranasal Administration
Autor: Hussein Akel, Gábor Katona, Edina Pallagi, Dorina Gabriella Dobó, Zoltán Kónya, Ildikó Csóka, Dániel Berkesi, Fakhara Sabir
Publikováno v: Molecules, Vol 26, Iss 1429, p 1429 (2021)
Molecules
Volume 26
Issue 5
The present study aimed to develop n-propyl gallate (PG)-encapsulated liposomes through a novel direct pouring method using the quality-by-design (QbD) approach. A further aim was to coat liposomes with hyaluronic acid (HA) to improve the stability o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e832eb8ba7b12d62dee068dd4aac3fd
https://pubmed.ncbi.nlm.nih.gov/33800788
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7
Formulation and In Vitro Comparison Study between Lipid-Based and Polymeric-Based Nanoparticles for Nose-to-Brain Delivery of a Model Drug for Alzheimer’s Disease
Autor: Ildikó Csóka, Hussein Akel
Publikováno v: The 1st International Electronic Conference on Pharmaceutics.
Certain challenges like the presence of highly complex structure (blood-brain barrier (BBB)), P-glycoprotein efflux, and the particular enzymatic activity stand in the way of the successful delivery of the drug moieties to the brain and make them fru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71c2fba88047bc433482c440c2c0a9a0
https://doi.org/10.3390/iecp2020-08680
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9
A comparison study of lipid and polymeric nanoparticles in the nasal delivery of meloxicam: Formulation, characterization, and in vitro evaluation
Autor: Ildikó Csóka, Gábor Katona, Fakhara Sabir, Rita Ambrus, Ruba Ismail, Hussein Akel
Publikováno v: International Journal of Pharmaceutics. 604:120724
With the increasingly widespread of central nervous system (CNS) disorders and the lack of sufficiently effective medication, meloxicam (MEL) has been reported as a possible medication for Alzheimer's disease (AD) management. Unfortunately, following
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfee85842b1730ad0807fabd2822a4d
https://doi.org/10.1016/j.ijpharm.2021.120724
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10
Progress and perspectives of brain-targeting lipid-based nanosystems via the nasal route in Alzheimer's disease
Autor: Ildikó Csóka, Hussein Akel, Ruba Ismail
Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 148
Since health care systems dedicate substantial resources to Alzheimer's disease (AD), it poses an increasing challenge to scientists and health care providers worldwide, especially that many decades of research in the medical field revealed no optima
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9964ed2741a9381294cb18219cf0c57
https://pubmed.ncbi.nlm.nih.gov/31926222
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