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GTP-cyclohydrolase-1 (GCH1) catalyses the rate-limiting step in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for enzymes including aromatic amino acid hydroxylases and nitric oxide synthases. Strategies that increase vascular
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656888
