Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hussam Jourdi"'
Autor:
Hussam Jourdi, Mohamed Kabbaj
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57124 (2013)
Brain-derived neurotrophic factor (BDNF) plays several prominent roles in synaptic plasticity and in learning and memory formation. Reduced BDNF levels and altered BDNF signaling have been reported in several brain diseases and behavioral disorders,
Externí odkaz:
https://doaj.org/article/f6b87b17d78e4de391208c21852bfddb
Autor:
Eun Hye Park, Hsin-Yi Kao, Hussam Jourdi, Milenna van Dijk, Simón Carrillo-Segura, Kayla W. Tunnell, Jeffrey Gutierrez, Emma J. Wallace, Matthew Troy-Regier, Basma Radwan, Edith Lesburguères, Juan Marcos Alarcon, André A Fenton
Publikováno v:
Biological Psychiatry Global Open Science.
BackgroundPhencyclidine (PCP) causes psychosis, is abused with increasing frequency, and was extensively used in antipsychotic drug discovery. PCP discoordinates hippocampal ensemble action potential discharge and impairs cognitive control in rats, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b087a4c15bbf8b4e61931f48949d3e7
https://doi.org/10.1016/j.bpsgos.2023.04.009
https://doi.org/10.1016/j.bpsgos.2023.04.009
Autor:
Yehia Mechref, Ohanes Ashekyan, Firas Kobeissy, Maya Wehbe, Dina Maaliki, Muhammad Ali Haidar, Maya Bizri, Hussam Jourdi, Ali H. Eid, Hassan Zaraket, Zena Wehbe, Stefania Mondello, Samar Abdelhady, Manal Fardoun, Zeinab Haj Hassan, Mark S. Gold, Shima Shahjouei, Ghassan Dbaibo
Publikováno v:
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 28(6)
SARS-CoV-2 infects cells through angiotensin-converting enzyme 2 (ACE2), a ubiquitous receptor that interacts with the virus’ surface S glycoprotein. Recent reports show that the virus affects the central nervous system (CNS) with symptoms and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b523e77631dac8763ff7dc28868ff80
https://pubmed.ncbi.nlm.nih.gov/34009067
https://pubmed.ncbi.nlm.nih.gov/34009067
Autor:
Leila Nasrallah, Helene Ismail, Mirna Sabra, Zaynab Shakkour, Stefania Mondello, Firas Kobeissy, Karl John Habashy, Hawraa Issa, Ohanes Ashekyan, Kazem Zibara, Eva Hamade, Hussam Jourdi
Edaravone is a potent free-radical scavenger that has been in the market for more than 30 years. It was originally developed in Japan to treat strokes and has been used there since 2001. Aside from its anti-oxidative effects, edaravone demonstrated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad40bd31db8bd5b376f7afdc9dc94414
http://hdl.handle.net/11570/3190456
http://hdl.handle.net/11570/3190456
Autor:
Caroline E. Strong, Ambalika Sarkar, Katherine N. Wright, Mohamed Kabbaj, Amanda M. Dossat, Hussam Jourdi
Publikováno v:
Neuroscience. 340:243-257
In humans, some males experience reductions in testosterone levels, as a natural consequence of aging or in the clinical condition termed hypogonadism, which are associated with impaired cognitive performance and mood disorder(s). Some of these behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a400aef46c0d68eff3cae31fc432c38f
https://doi.org/10.1016/j.neuroscience.2016.10.062
https://doi.org/10.1016/j.neuroscience.2016.10.062
Autor:
Hadi, Abou-El-Hassan, Fares, Sukhon, Edwyn Jeremy, Assaf, Hisham, Bahmad, Hussein, Abou-Abbass, Hussam, Jourdi, Firas H, Kobeissy
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1598
Degradomics has recently emerged as a subdiscipline in the omics era with a focus on characterizing signature breakdown products implicated in various disease processes. Driven by promising experimental findings in cancer, neuroscience, and metabolom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::570500d297810c6b762d367d6af7d07d
https://pubmed.ncbi.nlm.nih.gov/28508358
https://pubmed.ncbi.nlm.nih.gov/28508358
Autor:
Hadi Abou-El-Hassan, Hussam Jourdi, Fares Sukhon, Hisham F. Bahmad, Hussein Abou-Abbass, Edwyn Jeremy Assaf, Firas Kobeissy
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969500
Degradomics has recently emerged as a subdiscipline in the omics era with a focus on characterizing signature breakdown products implicated in various disease processes. Driven by promising experimental findings in cancer, neuroscience, and metabolom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b3da074e78ce1f404521ef859b4f302
https://doi.org/10.1007/978-1-4939-6952-4_4
https://doi.org/10.1007/978-1-4939-6952-4_4
Publikováno v:
The Journal of Neuroscience. 30:1086-1095
Calpain is a calcium-dependent protease that plays a significant role in synaptic plasticity, cell motility, and neurodegeneration. Two major calpain isoforms are present in brain, with μ-calpain (calpain1) requiring micromolar calcium concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e96e6ada3c2f695cabcbab63fd31adc8
https://doi.org/10.1523/jneurosci.5120-09.2010
https://doi.org/10.1523/jneurosci.5120-09.2010
Publikováno v:
Journal of Neuroscience. 29:8688-8697
Brain-derived neurotrophic factor (BDNF) stimulates local dendritic mRNA translation and is involved in formation and consolidation of memory. 2 H ,3 H ,6 aH -pyrrolidino\[2″,1″-3′,2′]1,3-oxazino[6′,5′-5,4]-benzo[ e ]1,4-dioxan-10-one (CX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bc2d8d5afcdba6e2edb4041f61e1a8
https://doi.org/10.1523/jneurosci.6078-08.2009
https://doi.org/10.1523/jneurosci.6078-08.2009
Publikováno v:
Neuropharmacology. 56:876-885
Neurotoxicity is involved in various neurodegenerative diseases including Parkinson's disease (PD), which affects mesencephalic dopaminergic neurons of the substantia nigra (SN). Positive alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e891cf7399025419d7206b951e4dc46e
https://doi.org/10.1016/j.neuropharm.2009.01.015
https://doi.org/10.1016/j.neuropharm.2009.01.015