Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hussam H Shaheen"'
Autor:
Hussam H Shaheen, Bianka Prinz, Ming-Tang Chen, Tej Pavoor, Song Lin, Nga Rewa Houston-Cummings, Renee Moore, Terrance A Stadheim, Dongxing Zha
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70190 (2013)
State-of-the-art monoclonal antibody (mAb) discovery methods that utilize surface display techniques in prokaryotic and eukaryotic cells require multiple steps of reformatting and switching of hosts to transition from display to expression. This resu
Externí odkaz:
https://doaj.org/article/af2ec7307fe942b5ae16b287fb069375
Autor:
Jiwon Jung, Bridget M Larkin, Gaurav Rajani, Minasri Borah, Celesztina Nagy-Domonkos, Weijie Zhou, Kevin L Otipoby, Joanne L Viney, Nathan Higginson-Scott, Ivan Mascanfroni, Hussam H Shaheen
Publikováno v:
The Journal of Immunology. 206:18.04-18.04
The complement system plays a major role in humoral innate immunity. Upon activation, complement proteins trigger a cascade of enzymatic events leading to the production of inflammatory mediators and membrane attack complexes. Tight regulation of com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e49ea8deec76487674539009a2dbbfa8
https://doi.org/10.4049/jimmunol.206.supp.18.04
https://doi.org/10.4049/jimmunol.206.supp.18.04
Autor:
Bridget M Larkin, Jyothsna Visweswaraiah, Bilian Li, Komal Pradhan, Michael Rowe, Gaurav Rajani, Celesztina Nagy-Domonkos, Nathan Higginson-Scott, Joanne L Viney, Kevin L Otipoby, Hussam H Shaheen, Ivan Mascanfroni
Publikováno v:
The Journal of Immunology. 206:28.20-28.20
Regulatory T cells (Treg) play a critical role in maintaining graft tolerance following organ transplantation, and increased numbers of Tregs in solid-tissue grafts such as the kidney are associated with improved graft survival and function. Therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3de40a01ab7f5d2eedf66a12743a1b
https://doi.org/10.4049/jimmunol.206.supp.28.20
https://doi.org/10.4049/jimmunol.206.supp.28.20
Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop
Autor:
Anita K. Hopper, Melanie A. Preston, Patrick A. Limbach, Michael P. Guy, Kady L. Krivos, Brandon Podyma, Hussam H. Shaheen, Eric M. Phizicky
Publikováno v:
RNA. 18:1921-1933
Post-transcriptional modification of the tRNA anticodon loop is critical for translation. Yeast Trm7 is required for 2′-O-methylation of C32 and N34 of tRNAPhe, tRNATrp, and tRNALeu(UAA) to form Cm32 and Nm34, and trm7-Δ mutants have severe growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5a30d232dec17419ac9c5ca60165c1
https://doi.org/10.1261/rna.035287.112
https://doi.org/10.1261/rna.035287.112
Autor:
Tsung Po Lai, Hsiao-Yun Huang, Anita K. Hopper, Hussam H. Shaheen, Athulaprabha Murthi, Eric M. Phizicky, Melanie A. Preston
Publikováno v:
Molecular Biology of the Cell
tRNAs traffic between the nucleus and the cytoplasm in response to nutrient availability. Using a new assay to track tRNA within cells, we show that tRNA nuclear import is constitutive, whereas tRNA reexport to the cytoplasm is regulated. Msn5 functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc76e547463d87e5ef7b3c8bfea5c20
http://europepmc.org/articles/PMC2820427
http://europepmc.org/articles/PMC2820427
Autor:
Gang Peng, Athulaprabha Murthi, Anita K. Hopper, Tsung Po Lai, Karen A. Stauffer, Nancy C. Martin, Hussam H. Shaheen
Publikováno v:
Traffic. 10:1243-1256
Trm1 is a tRNA specific m(2)(2)G methyltransferase shared by nuclei and mitochondria in Saccharomyces cerevisiae. In nuclei, Trm1 is peripherally associated with the inner nuclear membrane (INM). We investigated the mechanism delivering/tethering Trm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832e30c2ccf440e9b31026fc5fc9522a
https://doi.org/10.1111/j.1600-0854.2009.00956.x
https://doi.org/10.1111/j.1600-0854.2009.00956.x
Autor:
Anita K. Hopper, Hussam H. Shaheen
Publikováno v:
Trends in Cell Biology. 18:98-104
The biosynthesis of tRNA was previously thought to occur solely in the nucleus, with tRNA functioning only in the cytoplasm of eukaryotic cells. However, recent publications have reported that pre-tRNA splicing can occur in the cytoplasm, that aminoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2039c6c09c6b55230ec4a059e3708edd
https://doi.org/10.1016/j.tcb.2008.01.001
https://doi.org/10.1016/j.tcb.2008.01.001
Publikováno v:
Molecular Biology of the Cell. 18:2678-2686
Cytoplasmic tRNAs have recently been found to accumulate in the nucleus during amino acid starvation in yeast. The mechanism and regulation by which tRNAs return to the nucleus are unclear. Here, we show accumulation of cytoplasmic tRNA in the nucleu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419e08a90d352aa0a6b9461a911907a6
https://doi.org/10.1091/mbc.e07-01-0006
https://doi.org/10.1091/mbc.e07-01-0006
Autor:
Anita K. Hopper, Leonard S. Jefferson, Athulaprabha Murthi, Scot R. Kimball, Hussam H. Shaheen, Rick L. Horetsky
Publikováno v:
Proceedings of the National Academy of Sciences. 104:8845-8850
Until recently, transport of tRNA was presumed to be unidirectional, from the nucleus to the cytoplasm. Our published findings, however, revealed that cytoplasmic tRNAs move retrograde to the nucleus in Saccharomyces cerevisiae and that nuclear accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931e59bd49d4d5bae8fe49da776612aa
https://doi.org/10.1073/pnas.0700765104
https://doi.org/10.1073/pnas.0700765104
Autor:
Hussam H. Shaheen, Anita K. Hopper
Publikováno v:
Proceedings of the National Academy of Sciences. 102:11290-11295
In eukaryotes, tRNAs transcribed in the nucleus function in cytoplasmic protein synthesis. The Ran-GTP-binding exportin, Los1p/Xpo-t, and additional pathway(s) mediate tRNA transport to the cytoplasm. Although tRNA movement was thought to be unidirec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad699df63c8f1713b2c49c3c82f5d8ec
https://doi.org/10.1073/pnas.0503836102
https://doi.org/10.1073/pnas.0503836102