Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hussam Al-deen Ashab"'
Autor:
Hyun Kim, Mohammed Alshalalfa, Jean Hoffman-Censits, Costas D. Lallas, Elai Davicioni, Jianqing Lin, Ruth Birbe, Nicholas Erho, Jonathan Lehrer, Hussam Al-Deen Ashab, Mandeep Takhar, Anders Olson, Lucia L.C. Lam, W. Kevin Kelly, Karen E. Knudsen, Chellappagounder Thangavel, Roland Seiler, Felix Y. Feng, Edward M. Schaeffer, Edouard J. Trabulsi, Leonard G. Gomella, Mark D. Hurwitz, Adam P. Dicker, Robert B. Den
Publikováno v:
Urology Case Reports, Vol 9, Iss C, Pp 51-54 (2016)
Management of men with prostate cancer is fraught with uncertainty as physicians and patients balance efficacy with potential toxicity and diminished quality of life. Utilization of genomics as a prognostic biomarker has improved the informed decisio
Externí odkaz:
https://doaj.org/article/2c717d6f09b1472dbede2f384ec7c8f2
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
The genes in the collection of pathway signatures used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee73e4b4f4f3598762638929dd8171e
https://doi.org/10.1158/0008-5472.22411652
https://doi.org/10.1158/0008-5472.22411652
Autor:
Edward M. Schaeffer, Tamara L. Lotan, Felix Y. Feng, Elai Davicioni, Robert B. Den, Adam P. Dicker, Paul L. Nguyen, Eric A. Klein, Robert B. Jenkins, Firas Abdollah, Daniel E. Spratt, S. Laura Chang, Mandeep Takhar, Zaid Haddad, Jeffrey J. Tosoian, Shuang G. Zhao, Harrison Tsai, Kasra Yousefi, Ashley Ross, Bruce Trock, Mohammed Alshalalfa, Nicholas Erho, Hussam Al-Deen Ashab, Voleak Choeurng, Vidit Sharma, R. Jeffrey Karnes
Purpose: Currently, no genomic signature exists to distinguish men most likely to progress on adjuvant androgen deprivation therapy (ADT) after radical prostatectomy for high-risk prostate cancer. Here we develop and validate a gene expression signat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22237156074572ed068f5d3d23474add
https://doi.org/10.1158/1078-0432.c.6527052
https://doi.org/10.1158/1078-0432.c.6527052
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
Correlation of the PCS categories with clinical outcomes in individual cohorts displayed by Kaplan-Meier survival curves.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9746e0fda8e14382b8ee2e5a5a120d3c
https://doi.org/10.1158/0008-5472.22411664.v1
https://doi.org/10.1158/0008-5472.22411664.v1
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
Legends for Supplementary Figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc7f9a737e5b240d74accf7334c6f34
https://doi.org/10.1158/0008-5472.22411673.v1
https://doi.org/10.1158/0008-5472.22411673.v1
Autor:
Edward M. Schaeffer, Tamara L. Lotan, Felix Y. Feng, Elai Davicioni, Robert B. Den, Adam P. Dicker, Paul L. Nguyen, Eric A. Klein, Robert B. Jenkins, Firas Abdollah, Daniel E. Spratt, S. Laura Chang, Mandeep Takhar, Zaid Haddad, Jeffrey J. Tosoian, Shuang G. Zhao, Harrison Tsai, Kasra Yousefi, Ashley Ross, Bruce Trock, Mohammed Alshalalfa, Nicholas Erho, Hussam Al-Deen Ashab, Voleak Choeurng, Vidit Sharma, R. Jeffrey Karnes
Figure S1: Functional network of the 84 ADT-RS genes, with significant interaction with ADT, revealing high degree of connectivity for some ADT-RS genes like REST and EZH2, and several pathways potentially involved in ADT resistance mechanism. SOX2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9e8a2c2076f11d3225dde19f8a497a
https://doi.org/10.1158/1078-0432.22468782
https://doi.org/10.1158/1078-0432.22468782
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
Selection of the 37-gene panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4bcaa9b9795a6211e8667ad6da3fee
https://doi.org/10.1158/0008-5472.22411661
https://doi.org/10.1158/0008-5472.22411661
Autor:
Edward M. Schaeffer, Tamara L. Lotan, Felix Y. Feng, Elai Davicioni, Robert B. Den, Adam P. Dicker, Paul L. Nguyen, Eric A. Klein, Robert B. Jenkins, Firas Abdollah, Daniel E. Spratt, S. Laura Chang, Mandeep Takhar, Zaid Haddad, Jeffrey J. Tosoian, Shuang G. Zhao, Harrison Tsai, Kasra Yousefi, Ashley Ross, Bruce Trock, Mohammed Alshalalfa, Nicholas Erho, Hussam Al-Deen Ashab, Voleak Choeurng, Vidit Sharma, R. Jeffrey Karnes
Figure S2: Associations between PAM50 groups and ADT-RS signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc951cd28a660263e28aaae6a016d55
https://doi.org/10.1158/1078-0432.22468779.v1
https://doi.org/10.1158/1078-0432.22468779.v1
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
Boxplots depict distinct pathway activities between the subtypes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c546983a50afa1ae58ba334436ad916
https://doi.org/10.1158/0008-5472.22411670.v1
https://doi.org/10.1158/0008-5472.22411670.v1
Autor:
Michael R. Freeman, Jayoung Kim, Isla P. Garraway, Edward M. Schaeffer, Ashley E. Ross, Robert B. Den, Eric A. Klein, R. Jeffrey Karnes, Elai Davicioni, Hussam Al-deen Ashab, Mandeep Takhar, Mohammed Alshalalfa, Nicholas Erho, Beatrice S. Knudsen, Sungyong You
Differential enrichment of a benign prostate specific gene signature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b09ac8a98a3bef07b3be38d52a8af0
https://doi.org/10.1158/0008-5472.22411667.v1
https://doi.org/10.1158/0008-5472.22411667.v1