Identification of dimethyl 2,2'-((methylenebis(2-(2H-benzo[d][1,2,3]triazol-2-yl)-4-(2,4,4-trimethylpentan-2-yl)-6,1phenylene))bis(oxy))diacetate (TAJ4) as antagonist of NEK-Family: a future for potential drug discovery.

Autor: Aziz M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan., Ejaz SA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan. abida.ejaz@iub.edu.pk., Channar PA; Department of Basic Science and Humanities, Faculty of Information Science Humanities, Dawood University of Engineering and Technology Karachi, Karachi, 74800, Pakistan., Alkhathami AG; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O.Box 61413, Abha, 9088, Saudi Arabia., Qadri T; Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan., Hussain Z; Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan., Hussaain M; Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan., Ujan R; Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, Pakistan.

Publikováno v: BMC cancer [BMC Cancer] 2024 Dec 18; Vol. 24 (1), pp. 1521. Date of Electronic Publication: 2024 Dec 18.