Acetyl-CoA carboxylase inhibitor increases LDL-apoB production rate in NASH with cirrhosis: prevention by fenofibrate

Autor: Mohamad Dandan, Julia Han, Sabrina Mann, Rachael Kim, Kelvin Li, Hussein Mohammed, Jen-Chieh Chuang, Kaiyi Zhu, Andrew N. Billin, Ryan S. Huss, Chuhan Chung, Robert P. Myers, Marc Hellerstein

Publikováno v: Journal of Lipid Research, Vol 64, Iss 3, Pp 100339- (2023)

Treatment with acetyl-CoA carboxylase inhibitors (ACCi) in nonalcoholic steatohepatitis (NASH) may increase plasma triglycerides (TGs), with variable changes in apoB concentrations. ACC is rate limiting in de novo lipogenesis and regulates fatty acid

Externí odkaz: https://doaj.org/article/1b47be019904410e833c7ff617ad7ca5

Locally Markov walks on finite graphs

Autor: Kaiser, Robin, Levine, Lionel, Sava-Huss, Ecaterina

Locally Markov walks are natural generalizations of classical Markov chains, where instead of a particle moving independently of the past, it decides where to move next depending on the last action performed at the current location. We introduce the

Externí odkaz: http://arxiv.org/abs/2412.13766

The Ni isotopic composition of Ryugu reveals a common accretion region for carbonaceous chondrites

Autor: Spitzer, Fridolin, Kleine, Thorsten, Burkhardt, Christoph, Hopp, Timo, Yokoyama, Tetsuya, Abe, Yoshinari, Aléon, Jérôme, Alexander, Conel M. O'D., Amari, Sachiko, Amelin, Yuri, Bajo, Ken-ichi, Bizzarro, Martin, Bouvier, Audrey, Carlson, Richard W., Chaussidon, Marc, Choi, Byeon-Gak, Dauphas, Nicolas, Davis, Andrew M., Di Rocco, Tommaso, Fujiya, Wataru, Fukai, Ryota, Gautam, Ikshu, Haba, Makiko K., Hibiya, Yuki, Hidaka, Hiroshi, Homma, Hisashi, Hoppe, Peter, Huss, Gary R., Ichida, Kiyohiro, Iizuka, Tsuyoshi, Ireland, Trevor R., Ishikawa, Akira, Itoh, Shoichi, Kawasaki, Noriyuki, Kita, Noriko T., Kitajima, Kouki, Komatani, Shintaro, Krot, Alexander N., Liu, Ming-Chang, Masuda, Yuki, Morita, Mayu, Moynier, Fréderic, Motomura, Kazuko, Nakai, Izumi, Nagashima, Kazuhide, Nguyen, Ann, Nittler, Larry, Onose, Morihiko, Pack, Andreas, Park, Changkun, Piani, Laurette, Qin, Liping, Russell, Sara S., Sakamoto, Naoya, Schönbächler, Maria, Tafla, Lauren, Tang, Haolan, Terada, Kentaro, Terada, Yasuko, Usui, Tomohiro, Wada, Sohei, Wadhwa, Meenakshi, Walker, Richard J., Yamashita, Katsuyuki, Yin, Qing-Zhu, Yoneda, Shigekazu, Young, Edward D., Yui, Hiroharu, Zhang, Ai-Cheng, Nakamura, Tomoki, Naraoka, Hiroshi, Noguchi, Takaaki, Okazaki, Ryuji, Sakamoto, Kanako, Yabuta, Hikaru, Abe, Masanao, Miyazaki, Akiko, Nakato, Aiko, Nishimura, Masahiro, Okada, Tatsuaki, Yada, Toru, Yogata, Kasumi, Nakazawa, Satoru, Saiki, Takanao, Tanaka, Satoshi, Terui, Fuyuto, Tsuda, Yuichi, Watanabe, Sei-ichiro, Yoshikawa, Makoto, Tachibana, Shogo, Yurimoto, Hisayoshi

Publikováno v: Science Advances 10, 39, eadp2426 (2024)

The isotopic compositions of samples returned from Cb-type asteroid Ryugu and Ivuna-type (CI) chondrites are distinct from other carbonaceous chondrites, which has led to the suggestion that Ryugu and CI chondrites formed in a different region of the

Externí odkaz: http://arxiv.org/abs/2410.04192

Les Houches 2023: Physics at TeV Colliders: Standard Model Working Group Report

Autor: Andersen, J., Assi, B., Asteriadis, K., Azzurri, P., Barone, G., Behring, A., Benecke, A., Bhattacharya, S., Bothmann, E., Caletti, S., Chen, X., Chiesa, M., Cooper-Sarkar, A., Cridge, T., Gomez, A. Cueto, Datta, S., Dhani, P. K., Donega, M., Engel, T., Ravasio, S. Ferrario, Forte, S., Francavilla, P., Garzelli, M. V., Ghira, A., Ghosh, A., Giuli, F., Gouskos, L., Gras, P., Gütschow, C., Haddad, Y., Harland-Lang, L., Hekhorn, F., Helenius, I., Hinzmann, A., Höche, S., Holguin, J., Huss, A., Huston, J., Ježo, T., Jones, S., Kiebacher, S., Knobbe, M., Kogler, R., Köneke, K., Kunz, L., LeBlanc, M., Loch, P., Centeno, G. Loeschcke, Löschner, M., Maas, A., Magni, G., Maier, A., Marcoli, M., Marzani, S., McFayden, J., Meinzinger, P., Mikuni, V., Moch, S., Nadolsky, P., Napoletano, D., Pellen, M., Plätzer, S., Poncelet, R., Preuss, C., Qu, H., Rabbertz, K., Reichelt, D., Rescia, A., Roloff, J., Röntsch, R., Cruz, S. Sanchez, Sarkar, T., Scyboz, L., Sforza, F., Siódmok, A., Stagnitto, G., Tarek, A., Thorne, R. S., Valassi, A., Whitehead, J., Winter, J., Delaunay, C., Herrmann, B., Re, E.

This report presents a short summary of the activities of the "Standard Model" working group for the "Physics at TeV Colliders" workshop (Les Houches, France, 12-30 June, 2023).
Comment: Proceedings of the Standard Model Working Group of the 202

Externí odkaz: http://arxiv.org/abs/2406.00708

JUNO Sensitivity to Invisible Decay Modes of Neutrons

Autor: JUNO Collaboration, Abusleme, Angel, Adam, Thomas, Adamowicz, Kai, Ahmad, Shakeel, Ahmed, Rizwan, Aiello, Sebastiano, An, Fengpeng, An, Qi, Andronico, Giuseppe, Anfimov, Nikolay, Antonelli, Vito, Antoshkina, Tatiana, de André, João Pedro Athayde Marcondes, Auguste, Didier, Bai, Weidong, Balashov, Nikita, Baldini, Wander, Barresi, Andrea, Basilico, Davide, Baussan, Eric, Bellato, Marco, Beretta, Marco, Bergnoli, Antonio, Bick, Daniel, Bieger, Lukas, Biktemerova, Svetlana, Birkenfeld, Thilo, Blake, Iwan, Blyth, Simon, Bolshakova, Anastasia, Bongrand, Mathieu, Breton, Dominique, Brigatti, Augusto, Brugnera, Riccardo, Bruno, Riccardo, Budano, Antonio, Busto, Jose, Cabrera, Anatael, Caccianiga, Barbara, Cai, Hao, Cai, Xiao, Cai, Yanke, Cai, Zhiyan, Callier, Stéphane, Calvez, Steven, Cammi, Antonio, Campeny, Agustin, Cao, Chuanya, Cao, Guofu, Cao, Jun, Caruso, Rossella, Cerna, Cédric, Cerrone, Vanessa, Chang, Jinfan, Chang, Yun, Chatrabhuti, Auttakit, Chen, Chao, Chen, Guoming, Chen, Pingping, Chen, Shaomin, Chen, Xin, Chen, Yiming, Chen, Yixue, Chen, Yu, Chen, Zelin, Chen, Zhangming, Chen, Zhiyuan, Chen, Zikang, Cheng, Jie, Cheng, Yaping, Cheng, Yu Chin, Chepurnov, Alexander, Chetverikov, Alexey, Chiesa, Davide, Chimenti, Pietro, Chin, Yen-Ting, Chou, Po-Lin, Chu, Ziliang, Chukanov, Artem, Claverie, Gérard, Clementi, Catia, Clerbaux, Barbara, Molla, Marta Colomer, Di Lorenzo, Selma Conforti, Coppi, Alberto, Corti, Daniele, Csakli, Simon, Cui, Chenyang, Corso, Flavio Dal, Dalager, Olivia, Datta, Jaydeep, De La Taille, Christophe, Deng, Zhi, Deng, Ziyan, Ding, Xiaoyu, Ding, Xuefeng, Ding, Yayun, Dirgantara, Bayu, Dittrich, Carsten, Dmitrievsky, Sergey, Dohnal, Tadeas, Dolzhikov, Dmitry, Donchenko, Georgy, Dong, Jianmeng, Doroshkevich, Evgeny, Dou, Wei, Dracos, Marcos, Druillole, Frédéric, Du, Ran, Du, Shuxian, Duan, Yujie, Dugas, Katherine, Dusini, Stefano, Duyang, Hongyue, Eck, Jessica, Enqvist, Timo, Fabbri, Andrea, Fahrendholz, Ulrike, Fan, Lei, Fang, Jian, Fang, Wenxing, Fedoseev, Dmitry, Feng, Li-Cheng, Feng, Qichun, Ferraro, Federico, Fournier, Amélie, Fritsch, Fritsch, Gan, Haonan, Gao, Feng, Garfagnini, Alberto, Gavrikov, Arsenii, Giammarchi, Marco, Giudice, Nunzio, Gonchar, Maxim, Gong, Guanghua, Gong, Hui, Gornushkin, Yuri, Grassi, Marco, Gromov, Maxim, Gromov, Vasily, Gu, Minghao, Gu, Xiaofei, Gu, Yu, Guan, Mengyun, Guan, Yuduo, Guardone, Nunzio, Guizzetti, Rosa Maria, Guo, Cong, Guo, Wanlei, Hagner, Caren, Han, Hechong, Han, Ran, Han, Yang, He, Jinhong, He, Miao, He, Wei, He, Xinhai, Heinz, Tobias, Hellmuth, Patrick, Heng, Yuekun, Herrera, Rafael, Hor, YuenKeung, Hou, Shaojing, Hsiung, Yee, Hu, Bei-Zhen, Hu, Hang, Hu, Jun, Hu, Peng, Hu, Shouyang, Hu, Tao, Hu, Yuxiang, Hu, Zhuojun, Huang, Guihong, Huang, Hanxiong, Huang, Jinhao, Huang, Junting, Huang, Kaixuan, Huang, Shengheng, Huang, Wenhao, Huang, Xin, Huang, Xingtao, Huang, Yongbo, Hui, Jiaqi, Huo, Lei, Huo, Wenju, Huss, Cédric, Hussain, Safeer, Imbert, Leonard, Ioannisian, Ara, Isocrate, Roberto, Jafar, Arshak, Jelmini, Beatrice, Jeria, Ignacio, Ji, Xiaolu, Jia, Huihui, Jia, Junji, Jian, Siyu, Jiang, Cailian, Jiang, Di, Jiang, Guangzheng, Jiang, Wei, Jiang, Xiaoshan, Jiang, Xiaozhao, Jiang, Yixuan, Jing, Xiaoping, Jollet, Cécile, Kang, Li, Karaparabil, Rebin, Kazarian, Narine, Khan, Ali, Khatun, Amina, Khosonthongkee, Khanchai, Korablev, Denis, Kouzakov, Konstantin, Krasnoperov, Alexey, Kuleshov, Sergey, Kumaran, Sindhujha, Kutovskiy, Nikolay, Labit, Loïc, Lachenmaier, Tobias, Lai, Haojing, Landini, Cecilia, Leblanc, Sébastien, Lefevre, Frederic, Lei, Ruiting, Leitner, Rupert, Leung, Jason, Li, Demin, Li, Fei, Li, Fule, Li, Gaosong, Li, Hongjian, Li, Huang, Li, Jiajun, Li, Min, Li, Nan, Li, Qingjiang, Li, Ruhui, Li, Rui, Li, Shanfeng, Li, Shuo, Li, Tao, Li, Teng, Li, Weidong, Li, Weiguo, Li, Xiaomei, Li, Xiaonan, Li, Xinglong, Li, Yi, Li, Yichen, Li, Yufeng, Li, Zhaohan, Li, Zhibing, Li, Ziyuan, Li, Zonghai, Liang, An-An, Liang, Hao, Liao, Jiajun, Liao, Yilin, Liao, Yuzhong, Limphirat, Ayut, Lin, Guey-Lin, Lin, Shengxin, Lin, Tao, Ling, Jiajie, Ling, Xin, Lippi, Ivano, Liu, Caimei, Liu, Fang, Liu, Fengcheng, Liu, Haidong, Liu, Haotian, Liu, Hongbang, Liu, Hongjuan, Liu, Hongtao, Liu, Hongyang, Liu, Jianglai, Liu, Jiaxi, Liu, Jinchang, Liu, Min, Liu, Qian, Liu, Qin, Liu, Runxuan, Liu, Shenghui, Liu, Shubin, Liu, Shulin, Liu, Xiaowei, Liu, Xiwen, Liu, Xuewei, Liu, Yankai, Liu, Zhen, Loi, Lorenzo, Lokhov, Alexey, Lombardi, Paolo, Lombardo, Claudio, Loo, Kai, Lu, Chuan, Lu, Haoqi, Lu, Jingbin, Lu, Junguang, Lu, Meishu, Lu, Peizhi, Lu, Shuxiang, Lu, Xianguo, Lubsandorzhiev, Bayarto, Lubsandorzhiev, Sultim, Ludhova, Livia, Lukanov, Arslan, Luo, Fengjiao, Luo, Guang, Luo, Jianyi, Luo, Shu, Luo, Wuming, Luo, Xiaojie, Lyashuk, Vladimir, Ma, Bangzheng, Ma, Bing, Ma, Qiumei, Ma, Si, Ma, Xiaoyan, Ma, Xubo, Maalmi, Jihane, Mai, Jingyu, Malabarba, Marco, Malyshkin, Yury, Mandujano, Roberto Carlos, Mantovani, Fabio, Mao, Xin, Mao, Yajun, Mari, Stefano M., Marini, Filippo, Martini, Agnese, Mayer, Matthias, Mayilyan, Davit, Mednieks, Ints, Meng, Yue, Meraviglia, Anita, Meregaglia, Anselmo, Meroni, Emanuela, Miramonti, Lino, Mohan, Nikhil, Montuschi, Michele, Reveco, Cristobal Morales, Nastasi, Massimiliano, Naumov, Dmitry V., Naumova, Elena, Navas-Nicolas, Diana, Nemchenok, Igor, Thi, Minh Thuan Nguyen, Nikolaev, Alexey, Ning, Feipeng, Ning, Zhe, Nunokawa, Hiroshi, Oberauer, Lothar, Ochoa-Ricoux, Juan Pedro, Olshevskiy, Alexander, Orestano, Domizia, Ortica, Fausto, Othegraven, Rainer, Paoloni, Alessandro, Parker, George, Parmeggiano, Sergio, Patsias, Achilleas, Pei, Yatian, Pelicci, Luca, Peng, Anguo, Peng, Haiping, Peng, Yu, Peng, Zhaoyuan, Percalli, Elisa, Perrin, Willy, Perrot, Frédéric, Petitjean, Pierre-Alexandre, Petrucci, Fabrizio, Pilarczyk, Oliver, Rico, Luis Felipe Piñeres, Popov, Artyom, Poussot, Pascal, Previtali, Ezio, Qi, Fazhi, Qi, Ming, Qi, Xiaohui, Qian, Sen, Qian, Xiaohui, Qian, Zhen, Qiao, Hao, Qin, Zhonghua, Qiu, Shoukang, Qu, Manhao, Qu, Zhenning, Ranucci, Gioacchino, Re, Alessandra, Rebii, Abdel, Redchuk, Mariia, Reina, Gioele, Ren, Bin, Ren, Jie, Ren, Yuhan, Ricci, Barbara, Rientong, Komkrit, Rifai, Mariam, Roche, Mathieu, Rodphai, Narongkiat, Romani, Aldo, Roskovec, Bedřich, Ruan, Xichao, Rybnikov, Arseniy, Sadovsky, Andrey, Saggese, Paolo, Sandanayake, Deshan, Sangka, Anut, Sava, Giuseppe, Sawangwit, Utane, Schever, Michaela, Schwab, Cédric, Schweizer, Konstantin, Selyunin, Alexandr, Serafini, Andrea, Settimo, Mariangela, Shao, Junyu, Sharov, Vladislav, Shi, Hexi, Shi, Jingyan, Shi, Yanan, Shutov, Vitaly, Sidorenkov, Andrey, Šimkovic, Fedor, Singhal, Apeksha, Sirignano, Chiara, Siripak, Jaruchit, Sisti, Monica, Smirnov, Mikhail, Smirnov, Oleg, Sokolov, Sergey, Songwadhana, Julanan, Soonthornthum, Boonrucksar, Sotnikov, Albert, Sreethawong, Warintorn, Stahl, Achim, Stanco, Luca, Stankevich, Konstantin, Steiger, Hans, Steinmann, Jochen, Sterr, Tobias, Stock, Matthias Raphael, Strati, Virginia, Strizh, Michail, Studenikin, Alexander, Su, Aoqi, Su, Jun, Sun, Guangbao, Sun, Shifeng, Sun, Xilei, Sun, Yongjie, Sun, Yongzhao, Sun, Zhengyang, Suwonjandee, Narumon, Takenaka, Akira, Tan, Xiaohan, Tang, Jian, Tang, Jingzhe, Tang, Qiang, Tang, Quan, Tang, Xiao, Hariharan, Vidhya Thara, Tkachev, Igor, Tmej, Tomas, Torri, Marco Danilo Claudio, Triossi, Andrea, Trzaska, Wladyslaw, Tung, Yu-Chen, Tuve, Cristina, Ushakov, Nikita, Vedin, Vadim, Venettacci, Carlo, Verde, Giuseppe, Vialkov, Maxim, Viaud, Benoit, Vollbrecht, Cornelius Moritz, von Sturm, Katharina, Vorobel, Vit, Voronin, Dmitriy, Votano, Lucia, Walker, Pablo, Wang, Caishen, Wang, Chung-Hsiang, Wang, En, Wang, Guoli, Wang, Hanwen, Wang, Jian, Wang, Jun, Wang, Li, Wang, Lu, Wang, Meng, Wang, Mingyuan, Wang, Qianchuan, Wang, Ruiguang, Wang, Sibo, Wang, Siguang, Wang, Wei, Wang, Wenshuai, Wang, Xi, Wang, Xiangyue, Wang, Yangfu, Wang, Yaoguang, Wang, Yi, Wang, Yifang, Wang, Yuanqing, Wang, Yuyi, Wang, Zhe, Wang, Zheng, Wang, Zhimin, Watcharangkool, Apimook, Wei, Wei, Wei, Wenlu, Wei, Yadong, Wei, Yuehuan, Wen, Liangjian, Weng, Jun, Wiebusch, Christopher, Wirth, Rosmarie, Wu, Chengxin, Wu, Diru, Wu, Qun, Wu, Yinhui, Wu, Yiyang, Wu, Zhi, Wurm, Michael, Wurtz, Jacques, Wysotzki, Christian, Xi, Yufei, Xia, Dongmei, Xian, Shishen, Xiang, Ziqian, Xiao, Fei, Xiao, Xiang, Xie, Xiaochuan, Xie, Yijun, Xie, Yuguang, Xin, Zhao, Xing, Zhizhong, Xu, Benda, Xu, Cheng, Xu, Donglian, Xu, Fanrong, Xu, Hangkun, Xu, Jiayang, Xu, Jilei, Xu, Jing, Xu, Jinghuan, Xu, Meihang, Xu, Xunjie, Xu, Yin, Xu, Yu, Yan, Baojun, Yan, Qiyu, Yan, Taylor, Yan, Xiongbo, Yan, Yupeng, Yang, Changgen, Yang, Chengfeng, Yang, Fengfan, Yang, Jie, Yang, Lei, Yang, Pengfei, Yang, Xiaoyu, Yang, Yifan, Yang, Yixiang, Yang, Zekun, Yao, Haifeng, Ye, Jiaxuan, Ye, Mei, Ye, Ziping, Yermia, Frédéric, You, Zhengyun, Yu, Boxiang, Yu, Chiye, Yu, Chunxu, Yu, Guojun, Yu, Hongzhao, Yu, Miao, Yu, Xianghui, Yu, Zeyuan, Yu, Zezhong, Yuan, Cenxi, Yuan, Chengzhuo, Yuan, Ying, Yuan, Zhenxiong, Yue, Baobiao, Zafar, Noman, Zamogilnyi, Kirill, Zavadskyi, Vitalii, Zeng, Fanrui, Zeng, Shan, Zeng, Tingxuan, Zeng, Yuda, Zhan, Liang, Zhang, Aiqiang, Zhang, Bin, Zhang, Binting, Zhang, Feiyang, Zhang, Hangchang, Zhang, Haosen, Zhang, Honghao, Zhang, Jialiang, Zhang, Jiawen, Zhang, Jie, Zhang, Jingbo, Zhang, Jinnan, Zhang, Junwei, Zhang, Lei, Zhang, Peng, Zhang, Ping, Zhang, Qingmin, Zhang, Shiqi, Zhang, Shu, Zhang, Shuihan, Zhang, Siyuan, Zhang, Tao, Zhang, Xiaomei, Zhang, Xin, Zhang, Xuantong, Zhang, Yibing, Zhang, Yinhong, Zhang, Yiyu, Zhang, Yongpeng, Zhang, Yu, Zhang, Yuanyuan, Zhang, Yumei, Zhang, Zhenyu, Zhang, Zhijian, Zhao, Jie, Zhao, Rong, Zhao, Runze, Zhao, Shujun, Zhao, Tianhao, Zheng, Hua, Zheng, Yangheng, Zhou, Jing, Zhou, Li, Zhou, Nan, Zhou, Shun, Zhou, Tong, Zhou, Xiang, Zhou, Xing, Zhu, Jingsen, Zhu, Kangfu, Zhu, Kejun, Zhu, Zhihang, Zhuang, Bo, Zhuang, Honglin, Zong, Liang, Zou, Jiaheng

We explore the bound neutrons decay into invisible particles (e.g., $n\rightarrow 3 \nu$ or $nn \rightarrow 2 \nu$) in the JUNO liquid scintillator detector. The invisible decay includes two decay modes: $ n \rightarrow { inv} $ and $ nn \rightarrow

Externí odkaz: http://arxiv.org/abs/2405.17792