Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Husein Hadeiba"'
Autor:
Denis Dermadi, Michael Bscheider, Kristina Bjegovic, Nicole H. Lazarus, Agata Szade, Husein Hadeiba, Eugene C. Butcher
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory sp
Externí odkaz:
https://doaj.org/article/0449d657d72b45c6875a37de6f11f54a
Autor:
Hanadie Yousef, Benoit Lehallier, Taylor Merkel, Marion S. Buckwalter, Michelle B. Chen, Tony Wyss-Coray, Vidhu Mathur, Andrew C. Yang, Kristy A. Zera, Ashley N Burke, Ramesh V. Nair, Markus Schwaninger, Elisabeth Berber, Eugene C. Butcher, Husein Hadeiba, Stephen R. Quake, Todd C. Peterson, Liana Bonanno, Cathrin J. Czupalla, Jakob Körbelin, Davis P. Lee, Judith Zandstra
Publikováno v:
Nature Medicine. 25:988-1000
An aged circulatory environment can activate microglia, reduce neural precursor cell activity and impair cognition in mice. We hypothesized that brain endothelial cells (BECs) mediate at least some of these effects. We observe that BECs in the aged m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f019fdc40c80ee8b1f0f84e728007479
https://doi.org/10.1038/s41591-019-0440-4
https://doi.org/10.1038/s41591-019-0440-4
Autor:
Michael Bscheider, Agata Szade, Denis Dermadi, Kristina Bjegovic, Husein Hadeiba, Nicole H. Lazarus, Eugene C. Butcher
Publikováno v:
iScience, Vol 23, Iss 2, Pp-(2020)
iScience, vol 23, iss 2
iScience
iScience, vol 23, iss 2
iScience
Summary High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful tool to elucidate developmental programs directing cell lineages. We introduce tSpace, an algorithm based on the concept of “trajectory spa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74446fb9552607851d9ccd6dd26bbf97
https://pubmed.ncbi.nlm.nih.gov/32058956
https://pubmed.ncbi.nlm.nih.gov/32058956
Autor:
Robert S. Negrin, Alexander Filatenkov, Antonia M.S. Müller, Mareike Florek, Judith A. Shizuru, Natascha J. Küpper, Jessica A. Linderman, Holbrook E Kohrt, Husein Hadeiba
Publikováno v:
The Journal of Immunology. 197:4151-4162
T cells are widely used to promote engraftment of hematopoietic stem cells (HSCs) during an allogeneic hematopoietic cell transplantation. Their role in overcoming barriers to HSC engraftment is thought to be particularly critical when patients recei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e43fa95a64cb444597c2dc8eca357e
https://doi.org/10.4049/jimmunol.1500715
https://doi.org/10.4049/jimmunol.1500715
Autor:
Kristina Bjegovic, Michael Bscheider, Denis Dermadi, Husein Hadeiba, Agata Szade, Nicole H. Lazarus, Eugene C. Butcher
High-dimensional single cell profiling coupled with computational modeling is emerging as a powerful means to elucidate developmental sequences and define genetic programs directing cell lineages. Here we introduce tSpace, an algorithm based on the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b4ab6ad8ce051ada014e19fc47e37b
https://doi.org/10.1101/336313
https://doi.org/10.1101/336313
Autor:
Hanadie, Yousef, Cathrin J, Czupalla, Davis, Lee, Michelle B, Chen, Ashley N, Burke, Kristy A, Zera, Judith, Zandstra, Elisabeth, Berber, Benoit, Lehallier, Vidhu, Mathur, Ramesh V, Nair, Liana N, Bonanno, Andrew C, Yang, Todd, Peterson, Husein, Hadeiba, Taylor, Merkel, Jakob, Körbelin, Markus, Schwaninger, Marion S, Buckwalter, Stephen R, Quake, Eugene C, Butcher, Tony, Wyss-Coray
Publikováno v:
Nature medicine. 25(6)
An aged circulatory environment can activate microglia, reduce neural precursor cell activity and impair cognition in mice. We hypothesized that brain endothelial cells (BECs) mediate at least some of these effects. We observe that BECs in the aged m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cba53fd34c59c3d71f0678b901c291d3
https://pubmed.ncbi.nlm.nih.gov/31138911
https://pubmed.ncbi.nlm.nih.gov/31138911
Autor:
K. Mark Ansel, Betty Diamond, Katharina Lahl, Mike Lee, Dirk Baumjohann, Sun Jung Kim, Husein Hadeiba, Eugene C. Butcher, John Morton, Ruizhu Zeng, Payal Watchmaker, Alexander L. Dent
Publikováno v:
Nature immunology, vol 15, iss 1
Dendritic cells (DCs) that orchestrate mucosal immunity have been studied in mice. Here we characterized human gut DC populations and defined their relationship to previously studied human and mouse DCs. CD103(+)Sirpα(-) DCs were related to human bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b4708dc18fd422bc39409471df334b
https://doi.org/10.1038/ni.2768
https://doi.org/10.1038/ni.2768
Autor:
Eugene C. Butcher, Husein Hadeiba
Publikováno v:
European Journal of Immunology. 43:1425-1429
Central tolerance is critical in establishing a peripheral T-cell repertoire purged of functional autoreactive T cells. One of the major requirements for effective central tolerance is the presentation of self and other innocuous antigens (Ags), incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247d4af2e70c5096f5293e8589186c65
https://doi.org/10.1002/eji.201243192
https://doi.org/10.1002/eji.201243192
Autor:
Gizette V. Sperinde, Brian A. Zabel, Christina D. Swanson, Nicole Tejeda, Andrew J. Gentles, J. Monnier, Alison K. Holzer, Husein Hadeiba, Eugene C. Butcher, Abdolhossein Edalati, Holbrook E Kohrt, Ash A. Alizadeh, Russell K. Pachynski
Publikováno v:
The Journal of Experimental Medicine
Chemerin recruits NK cells to suppress melanoma growth.
Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a
Infiltration of specialized immune cells regulates the growth and survival of neoplasia. Here, in a survey of public whole genome expression datasets we found that the gene for chemerin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde04cef5152f0efd5ab8bf26b0f76ed
https://doi.org/10.1084/jem.20112124
https://doi.org/10.1084/jem.20112124
Autor:
Linh P. Nguyen, Eugene C. Butcher, Husein Hadeiba, Russell K. Pachynski, Asma Ghodsi, Cecilia Oderup, Abdolhossein Edalati, Katharina Lahl, Aida Habtezion, Sarah Adler
Publikováno v:
Immunity. 36(3):438-450
Summary Central tolerance can be mediated by peripheral dendritic cells (DCs) that transport innocuous antigens (Ags) to the thymus for presentation to developing T cells, but the responsible DC subsets remained poorly defined. Immature plasmacytoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd65c7d2311778c9b5a1ece4a71a756