Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Huse Klaus"'
Autor:
Taudien Stefan, Gäbel Gabor, Kuss Oliver, Groth Marco, Grützmann Robert, Huse Klaus, Kluttig Alexander, Wolf Andreas, Nothnagel Michael, Rosenstiel Philip, Greiser Karin Halina, Werdan Karl, Krawczak Michael, Pilarsky Christian, Platzer Matthias
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 629 (2012)
Abstract Background Human ß-defensins are a family of antimicrobial peptides located at the mucosal surface. Both sequence multi-site variations (MSV) and copy-number variants (CNV) of the defensin-encoding genes are associated with increased risk f
Externí odkaz:
https://doaj.org/article/138c55bcca3d43f4975a41ec1bea671c
Autor:
Zhang Xinmin, Petzold Andreas, Raffaelli Francesca, Huse Klaus, Groth Marco, Felder Marius, Szafranski Karol, Taudien Stefan, Rosenstiel Philip, Hampe Jochen, Schreiber Stefan, Platzer Matthias
Publikováno v:
BMC Genomics, Vol 12, Iss 1, p 243 (2011)
Abstract Background In highly copy number variable (CNV) regions such as the human defensin gene locus, comprehensive assessment of sequence variations is challenging. PCR approaches are practically restricted to tiny fractions, and next-generation s
Externí odkaz:
https://doaj.org/article/0c71d151470e4aa1a2935a01928c5705
Autor:
Kramer Marcel, Boeck Janne, Reichenbach Daniela, Kaether Christoph, Schreiber Stefan, Platzer Matthias, Rosenstiel Philip, Huse Klaus
Publikováno v:
BMC Research Notes, Vol 3, Iss 1, p 224 (2010)
Abstract Background The innate immune system employs several receptor families that form the basis of sensing pathogen-associated molecular patterns. NOD (nucleotide-binding and oligomerization domain) like receptors (NLRs) comprise a group of cytoso
Externí odkaz:
https://doaj.org/article/ce3191667faa4e36ba1d500b0e2a790a
Autor:
Rosenstiel Philip, Hampe Jochen, Szafranski Karol, Petzold Andreas, Huse Klaus, Groth Marco, Taudien Stefan, Schreiber Stefan, Platzer Matthias
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 252 (2010)
Abstract Background The beta-defensin gene cluster (DEFB) at chromosome 8p23.1 is one of the most copy number (CN) variable regions of the human genome. Whereas individual DEFB CNs have been suggested as independent genetic risk factors for several d
Externí odkaz:
https://doaj.org/article/37ff71ef4a79447dbc84c48625e83dde
Autor:
Hampe Jochen, Rosenstiel Philip, Huse Klaus, Szafranski Karol, Friedel Swetlana, Gausmann Ulrike, Jahn Niels, Lenser Thorsten, Sinha Rileen, Schuster Stefan, Hiller Michael, Backofen Rolf, Platzer Matthias
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 216 (2010)
Abstract Background Subtle alternative splicing events involving tandem splice sites separated by a short (2-12 nucleotides) distance are frequent and evolutionarily widespread in eukaryotes, and a major contributor to the complexity of transcriptome
Externí odkaz:
https://doaj.org/article/ef9d35cb7efa4f98bb6a454094490f59
Publikováno v:
BMC Evolutionary Biology, Vol 8, Iss 1, p 89 (2008)
Abstract Background Alternative selection of splice sites in tandem donors and acceptors is a major mode of alternative splicing. Here, we analyzed whether in-frame tandem sites leading to subtle mRNA insertions/deletions of 3, 6, or 9 nucleotides ar
Externí odkaz:
https://doaj.org/article/bf52e17b906f41629035b2972fd89be9
Autor:
Mathew Christopher G, Roberts Roland G, Platzer Cornelia, Reichwald Kathrin, Hampe Jochen, Franke Andre, Huse Klaus, Rosenstiel Philip, Platzer Matthias, Schreiber Stefan
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 472 (2007)
Abstract Background NOD2 is an innate immune receptor for the bacterial cell wall component muramyl-dipeptide. Mutations in the leucine-rich repeat region of NOD2, which lead to an impaired recognition of muramyl-dipeptide, have been associated with
Externí odkaz:
https://doaj.org/article/7b2d2a2926ef46899e8f471b93277ded
Autor:
Loncarevic Ivan F, Frankish Adam, Asakawa Shuichi, Shimizu Atsushi, Szafranski Karol, Schilhabel Markus, Reichwald Kathrin, Huse Klaus, Galgoczy Petra, Taudien Stefan, Shimizu Nobuyoshi, Siddiqui Roman, Platzer Matthias
Publikováno v:
BMC Genomics, Vol 5, Iss 1, p 92 (2004)
Abstract Background Defensins are important components of innate immunity to combat bacterial and viral infections, and can even elicit antitumor responses. Clusters of defensin (DEF) genes are located in a 2 Mb range of the human chromosome 8p23.1.
Externí odkaz:
https://doaj.org/article/dc6c0727e1ae44c7b1ea0ddd2e0d0eee
Autor:
Retsas, Theodoros, Huse, Klaus, Lazaridis, Lazaros-Dimitrios, Karampela, Niki, Bauer, Michael, Platzer, Matthias, Kolonia, Virginia, Papageorgiou, Eirini, Giamarellos-Bourboulis, Evangelos J., Dimopoulos, George
Publikováno v:
In International Journal of Infectious Diseases February 2018 67:102-106
Autor:
Hampe, Jochen, Frenzel, Henning, Mirza, Muddassar M., Cuthbert, Andrew, Mascheretti, Silvia, Huse, Klaus, Platzer, Matthias, Bridger, Stephen, Meyer, Birgit, Nürnberg, Peter, Stokkers, Pieter, Krawczak, Michael, Mathew, Christopher G., Curran, Mark, Schreiber, Stefan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2002 Jan 01. 99(1), 321-326.
Externí odkaz:
https://www.jstor.org/stable/3057536