Výsledky vyhledávání - "Husam M. Younes"

Akademický článek

Overview of Tissue Engineering and Drug Delivery Applications of Reactive Electrospinning and Crosslinking Techniques of Polymeric Nanofibers with Highlights on Their Biocompatibility Testing and Regulatory Aspects

Autor: Husam M. Younes, Hana Kadavil, Hesham M. Ismail, Sandi Ali Adib, Somayeh Zamani, Raid G. Alany, Ali A. Al-Kinani

Publikováno v: Pharmaceutics, Vol 16, Iss 1, p 32 (2023)

Traditional electrospinning is a promising technique for fabricating nanofibers for tissue engineering and drug delivery applications. The method is highly efficient in producing nanofibers with morphology and porosity similar to the extracellular ma

Externí odkaz: https://doaj.org/article/4ef70019ee95484d879b592a75fda86f

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Akademický článek

Formulation of Lipid-Based Tableted Spray-Congealed Microparticles for Sustained Release of Vildagliptin: In Vitro and In Vivo Studies

Autor: Khaled H. Al Zahabi, Hind Ben tkhayat, Ehab Abu-Basha, Al Sayed Sallam, Husam M. Younes

Publikováno v: Pharmaceutics, Vol 13, Iss 12, p 2158 (2021)

Spray-congealing (SPC) technology was utilized to prepare lipid-based microparticles (MP) capable of sustaining the release of Vildagliptin (VG) for use as a once-daily treatment for type 2 diabetes mellitus. VG microparticles were prepared using Com

Externí odkaz: https://doaj.org/article/ee5a9b0495a1413d9f49fd35160eb7fe

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Development, characterization and stability evaluation of ciprofloxacin-loaded parenteral nutrition nanoemulsions

Autor: Ibrahim Tolaymat, Abdelbary Elhissi, Kirsty Palmer, Ammar Said Suliman, Husam M. Younes, Basel Arafat, Rose Tom, Mohammad Najlah

Publikováno v: Pharmaceutical Development and Technology. 25:579-587

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. In this study, two licensed total parenteral nanoemulsion formulations (Clinoleic® and Intralipid®) were loaded with ciprofloxacin (CP). The physicochemical characteristics and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ba6ebe10ae5332e75dc32f646c4ca7
https://doi.org/10.1080/10837450.2020.1720237

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Retinal cell regeneration using tissue engineered polymeric scaffolds

Autor: Maria Abedin Zadeh, Raid G. Alany, Mouhamad Khoder, Ali A. Al-Kinani, Husam M. Younes

Publikováno v: Drug Discovery Today. 24:1669-1678

Degenerative retinal diseases, such as age-related macular degeneration (AMD), can lead to permanent sight loss. Although intravitreal anti-vascular endothelial growth factor (VEGF) and steroid injections are effective for the management of early sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dff7dc1a51e0280a794f9f31a01c5fc
https://doi.org/10.1016/j.drudis.2019.04.009

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Synthesis, characterization & cytocompatibility of poly (diol-co-tricarballylate) based thermally crosslinked elastomers for drug delivery & tissue engineering applications

Autor: Somayeh Zamani, Husam M. Younes, Youmna M. Hassouna, Wael Kafienah

Publikováno v: Hassouna, Y M, Zamani, S, Kafienah, W & Younes, H M 2018, ' Synthesis, characterization & cytocompatibility of poly (diol-co-tricarballylate) based thermally crosslinked elastomers for drug delivery & tissue engineering applications ', Materials Science and Engineering C, vol. 93, pp. 254-264 . https://doi.org/10.1016/j.msec.2018.07.028

The aim of this study was to investigate the synthesis and in vitro characterization of thermoset biodegradable poly (diol-co-tricarballylate) (PDT) elastomeric polymers for the purpose of their use in implantable drug delivery and tissue engineering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a37b70a91db609fbcd3d75c266d12aa
https://doi.org/10.1016/j.msec.2018.07.028

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Controlled release of bioactive IL-2 from visible light photocured biodegradable elastomers for cancer immunotherapy applications

Autor: Mohamed A. Shaker, Jules J. E. Doré, Husam M. Younes

Biodegradable elastomeric controlled-release poly (decane-co-tricarballylate) (PDET) based matrices capable of maintaining the stability and bioactivity of Interleukin-2 (IL-2) through the utilization of visible-light curing and solvent-free loading

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483757b3c2a55c833b1e6d9475ffee74

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Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization

Autor: Mohammad Najlah, Mohamed A. Elrayess, Abdelbary Elhissi, Husam M. Younes, Nada Khudair, Abdelali Agouni

Slurry-based Letrozole (LTZ)-loaded proniosomes were designed using sucrose or sorbitol as carriers and various ratios of cholesterol (CH) and Tween 80 (T80) as lipid composition. Proniosomes were hydrated and probe-sonicated to generate nano-vesicle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51740a6ad0c4c857365123714f51302
https://www.sciencedirect.com/science/article/pii/S177322471931799X?v=s5

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Preparation and optimization of monodisperse polymeric microparticles using modified vibrating orifice aerosol generator for controlled delivery of letrozole in breast cancer therapy

Autor: Husam M. Younes, Abdelbary Elhissi, Mohamed A. Elrayess, Raid G. Alany, Bayan Alemrayat

Publikováno v: Drug Development and Industrial Pharmacy. 44:1953-1965

Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. In this work, and for the first time, using vibrating orifice aerosol generator (VOAG) technology, monodisperse poly-�-caprolactone (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dafece0c93b1aa28867baed01036e43f
https://doi.org/10.1080/03639045.2018.1503298

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