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pro vyhledávání: '"Husak, Antonija"'
Autor:
Husak, Antonija, Basarić, Nikola
Quinone methides (QMs) are reactive intermediates in the chemistry and photochemistry of phenols involved in a large number of chemical and biological processes such as enzyme inhibition, DNA alkylation and cross-linking [1]. Furthermore, it has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::20178130f5504a1687e19d214a4bcaec
https://www.bib.irb.hr/925011
https://www.bib.irb.hr/925011
Akademický článek
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Quinone methides (QMs) are recative intermediates with a potential in the development of new leads for drugs owing to their reactivity with DNA, proteins and enzymes [1]. In particular, some anticancer antibiotics such as mitomycine base their action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::b1ad4d3913e8617d850aef46174e1d01
https://www.bib.irb.hr/884230
https://www.bib.irb.hr/884230
Publikováno v:
Kemija u industriji : časopis kemičara i tehnologa Hrvatske
Kinon-metidi (QM, naziv po IUPAC-u: kinometani) su reaktivni međuprodukti koji su povezani s biološkom aktivnosti brojnih prirodnih i sintetski dobivenih spojeva. Njihova aktivnost temelji se na inhibiciji enzima ili, češće, na alkilaciji/križn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2584::e750b8b103587fc1951d78d14c93c78f
http://fulir.irb.hr/3999/
http://fulir.irb.hr/3999/
Peptides were not commonly encountered as drugs because of difficulty to penetrate through cell membranes and proteolysis by intracellular enzymes. However, these problems have been circumvented by structural modifications, and particularly incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::4367795d234f1da2b1de088418f25592
https://www.bib.irb.hr/808671
https://www.bib.irb.hr/808671
Autor:
Husak, Antonija
Peptide therapeutics are starting to show a maturity that reflects their potential for addressing a growing range of medical challenges and about half of the peptides in clinical trials target indications in oncology, metabolic, cardiovascular and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::51d83dacf3f41e207ba070dbf5429cb9
https://www.bib.irb.hr/825228
https://www.bib.irb.hr/825228
Peptidi se u posljednje vrijeme intenzivno istražuju jer se pokazalo da mogu biti korisni u liječenju niza bolesti uključujući tumorske bolesti, bakterijske i virusne infekcije. U svrhu razvoja lijekova za navedene bolesti važno je proučiti int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::d24a0a9fd69bfc91abcaf4858c880e3e
https://www.bib.irb.hr/808676
https://www.bib.irb.hr/808676
Autor:
Husak, Antonija
U cilju proučavanja utjecaja heterocikličke jezgre kao supstituenta na fotokemijsko ponašanje konjugiranih butadienskih sustava, Wittigovom reakcijom sintetizirani su novi piridinski derivati butadiena 3-[4-(2-vinilfenil)buta-1,3-dienil]piridin (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8f72e3052c884041495a7376ad60faaf
https://repozitorij.fkit.unizg.hr/islandora/object/fkit:4
https://repozitorij.fkit.unizg.hr/islandora/object/fkit:4
Autor:
Zrnčić, Mirta, Husak, Antonija, Varga, Ines, Babić, Sandra, Ljubas, Davor, Kaštelan-Macan, Marija
Farmaceutici se svakodnevno upotrebljavaju u velikim količinama te se stoga kontinuirano unose u okoliš. Iako su koncentracije farmaceutika određene u okolišu male, još uvijek se ispituje utjecaj kontinuirane izloženosti i tako malim koncentrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::e72cc97ccd6039adb87e92fe394e6099
https://www.bib.irb.hr/689391
https://www.bib.irb.hr/689391
Autor:
Husak, Antonija
Danas se farmaceutici prisutni u okolišu smatraju zagađivalima okoliša. Nakon primjene farmaceutici dospijevaju u okoliš na razne načine. Jedan od načina je izlučivanjem, bilo u nepromijenjenom obliku ili u obliku metabolita. U najvećoj mjeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::a9fb54476fa20470b707af4c4277511e
https://www.bib.irb.hr/642500
https://www.bib.irb.hr/642500