Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hursch Patel"'
Autor:
Hursch Patel, Karine Dubé
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 3, Pp 100339- (2023)
The use of broadly neutralizing antibodies (bNAbs) as a cure-related research strategy for human immunodeficiency virus (HIV) has gained attention from the scientific community. bNAbs are specialized antibodies that target HIV-1 by binding to protein
Externí odkaz:
https://doaj.org/article/5e7077a862a540fd86ec8a3b6dd600fd
Autor:
Karine Dubé, Harsh Agarwal, William B. Carter, Lynda Dee, Jeff Taylor, Christopher Roebuck, Beth Peterson, Hursch Patel, Samuel Ndukwe, Kenneth M. Lynn, Linden Lalley-Chareczko, Emily Hiserodt, Sukyung Kim, Daniel Rosenbloom, Brad R. Evans, Melanie Anderson, Daria J. Hazuda, Kevin Bateman, Bonnie J. Howell, Livio Azzoni, Karam Mounzer, Pablo Tebas, Luis J. Montaner
Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 76-90 (2022)
Background: HIV cure-directed clinical trials using analytical treatment interruptions (ATIs) require participants to adhere to frequent monitoring visits for viral load tests. Novel viral load monitoring strategies are needed to decrease participant
Externí odkaz:
https://doaj.org/article/05fbd233a40d4f83afda13ea5699851d
Autor:
Karine Dubé, Brittany Shelton, Hursch Patel, Samuel O. Ndukwe, Susanna Concha-Garcia, Cheryl Dullano, Stephanie Solso, Steven Hendrickx, Andy Kaytes, Jeff Taylor, Thomas J. Villa, Susan J. Little, Patricia K. Riggs, David Lessard, Anish K. Arora, Cecilia T. Costiniuk, Shadi Eskaf, Davey M. Smith, Sara Gianella
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 2, Pp 100328- (2023)
Introduction: Although current antiretroviral therapy allows most people with HIV (PWH) to experience normal longevity with a good quality of life, an HIV cure remains elusive due to HIV reservoir formation within deep tissues. An HIV cure remains hi
Externí odkaz:
https://doaj.org/article/4efada383d2c44e395d7146547e72941
Publikováno v:
HIV Research & Clinical Practice, Vol 23, Iss 1, Pp 61-75 (2022)
Background: Research on stakeholder perspectives of HIV cure research has involved people with HIV (PWH), who generally cite the importance of HIV clinician advice in making decisions about trial participation. However, there has been little explorat
Externí odkaz:
https://doaj.org/article/912e814585a349f1a1221d4618e6b404
Autor:
Karine Dubé, John Kanazawa, Hursch Patel, Michael Louella, Laurie Sylla, Jeff Sheehy, Lynda Dee, Jeff Taylor, Jen Adair, Kim Anthony-Gonda, Boro Dropulić, John A. Sauceda, Michael J. Peluso, Steven G. Deeks, Jane Simoni
Publikováno v:
BMC Medical Ethics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background HIV cure research involving cell and gene therapy has intensified in recent years. There is a growing need to identify ethical standards and safeguards to ensure cell and gene therapy (CGT) HIV cure research remains valued and acc
Externí odkaz:
https://doaj.org/article/f7bf2f0c25664f168230bc9dc1a4b9d9
Autor:
John Kanazawa, Sara Gianella, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Christopher Christensen, Hursch Patel, Samuel Ndukwe, Stephen A. Rawlings, Steven Hendrickx, Susan Little, Brandon Brown, Davey Smith, Karine Dubé
Publikováno v:
BMC Medical Ethics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background One of the next frontiers in HIV research is focused on finding a cure. A new priority includes people with HIV (PWH) with non-AIDS terminal illnesses who are willing to donate their bodies at the end-of-life (EOL) to advance the
Externí odkaz:
https://doaj.org/article/ee341c50d8c1468499212ea22cea5a63
Autor:
Karine Dubé, John Kanazawa, Jeff Taylor, Lynda Dee, Nora Jones, Christopher Roebuck, Laurie Sylla, Michael Louella, Jan Kosmyna, David Kelly, Orbit Clanton, David Palm, Danielle M. Campbell, Morénike Giwa Onaiwu, Hursch Patel, Samuel Ndukwe, Laney Henley, Mallory O. Johnson, Parya Saberi, Brandon Brown, John A. Sauceda, Jeremy Sugarman
Publikováno v:
BMC Medical Ethics, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background The pursuit of a cure for HIV is a high priority for researchers, funding agencies, governments and people living with HIV (PLWH). To date, over 250 biomedical studies worldwide are or have been related to discovering a safe, effe
Externí odkaz:
https://doaj.org/article/07f6f61cbb5a4380b506701dd273bf3a
Autor:
Sogol S Javadi, Kushagra Mathur, Susanna Concha-Garcia, Hursch Patel, Kelly E Perry, Megan Lo, Jeff Taylor, Andy Kaytes, Susan Little, Sara Gianella, Davey Smith, Karine Dubé
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250882 (2021)
As end-of-life (EOL) HIV cure-related research expands, understanding perspectives of participants' next-of-kin (NOK) is critical to maintaining ethical study conduct. We conducted two small focus groups and two one-on-one interviews using focus grou
Externí odkaz:
https://doaj.org/article/66aac9ec4042441dbe5d673305723409
Autor:
John Kanazawa, Sara Gianella, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Christopher Christensen, Hursch Patel, Samuel Ndukwe, Stephen Rawlings, Steven Hendrickx, Susan Little, Brandon Brown, Davey Smith, Karine Dubé
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254148 (2021)
BackgroundA unique window of opportunity currently exists to generate ethical and practical considerations presented by interventional HIV cure-related research at the end-of-life (EOL). Because participants would enroll in these studies for almost c
Externí odkaz:
https://doaj.org/article/085d198d99df48ac9490a4186d499b92
Autor:
Karine Dubé, Kelly E. Perry, Kushagra Mathur, Megan Lo, Sogol S. Javadi, Hursch Patel, Susanna Concha-Garcia, Jeff Taylor, Andy Kaytes, Lynda Dee, Danielle Campbell, John Kanazawa, David Smith, Sara Gianella, Judith D. Auerbach, Parya Saberi, John A. Sauceda
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 4, Pp 100008- (2020)
Introduction: The question of what motivates people to participate in research is particularly salient in the HIV field. While participation in HIV research was driven by survival in the 1980’s and early 1990’s, access to novel therapies became t
Externí odkaz:
https://doaj.org/article/10c10163618e4a5ab422f4c1c56d1cd7