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Autor:
Krieger IV; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States., Yalamanchili S; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Dickson P; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Engelhart CA; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10021, United States., Zimmerman MD; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Wood J; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States., Clary E; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States., Nguyen J; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States., Thornton N; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10021, United States., Centrella PA; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Chan B; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Auron Therapeutics, 55 Chapel Street, Newton, Massachusetts 02458, United States., Cuozzo JW; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Relay Therapeutics, 399 Binney Street, Cambridge, Massachusetts 02141, United States., Gengenbacher M; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Guié MA; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Guilinger JP; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Bienstock C; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Hartl H; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Orogen Therapeutics, 12 Gill Street, Woburn, Massachusetts 01801, United States., Hupp CD; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Ipsen Bioscience Inc., 1 Main Street, Cambridge, Massachusetts 02142, United States., Jetson R; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Valo Health, 75 Hayden Avenue, Lexington, Massachusetts 02141, United States., Satoh T; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; EXO Therapeutics, 150 Cambridgepark Drive, suite 300, Cambridge, Massachusetts 02140, United States., Yeoman JTS; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.; Recludix Pharmaceuticals, 222 Third Street, Cambridge, Massachusetts 02142, United States., Zhang Y; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Dartois V; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110, United States.; Hackensack Meridian School of Medicine, Hackensack Meridian Health, Nutley, New Jersey 07110, United States., Schnappinger D; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10021, United States., Keefe AD; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Sacchettini JC; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States.
Publikováno v:
ACS infectious diseases [ACS Infect Dis] 2024 May 10; Vol. 10 (5), pp. 1561-1575. Date of Electronic Publication: 2024 Apr 05.
Autor:
Hekking KFW; Symeres, 6546BB Nijmegen, The Netherlands., Maroto S; Symeres, 6546BB Nijmegen, The Netherlands., van Kekem K; Symeres, 6546BB Nijmegen, The Netherlands., Haasjes FS; Symeres, 6546BB Nijmegen, The Netherlands., Slootweg JC; Symeres, 6546BB Nijmegen, The Netherlands., Oude Alink PGB; Symeres, 6546BB Nijmegen, The Netherlands., Dirks R; Symeres, 6546BB Nijmegen, The Netherlands., Sardana M; Symeres, 6546BB Nijmegen, The Netherlands., Bolster MG; Symeres, 6546BB Nijmegen, The Netherlands., Kuijpers B; Symeres, 6546BB Nijmegen, The Netherlands., Smith D; Symeres, 6546BB Nijmegen, The Netherlands., Doodeman R; Symeres, 6546BB Nijmegen, The Netherlands., Scheepstra M; Symeres, 6546BB Nijmegen, The Netherlands., Zech B; X-Rx, Inc., New York, New York 10016, United States., Mulvihill M; X-Rx, Inc., New York, New York 10016, United States., Renzetti LM; X-Rx, Inc., New York, New York 10016, United States., Babiss L; X-Rx, Inc., New York, New York 10016, United States., Centrella PA; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Clark MA; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Cuozzo JW; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Guié MA; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Sigel E; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Habeshian S; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Hupp CD; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Liu J; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Thomson HA; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Keefe AD; X-Chem, Inc., Waltham, Massachusetts 02453, United States., Müller G; Symeres, 6546BB Nijmegen, The Netherlands., Gremmen S; Symeres, 6546BB Nijmegen, The Netherlands.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 3039-3065. Date of Electronic Publication: 2024 Feb 02.
Autor:
Fair RJ; X-Chem Inc., 100 Beaver Street, Waltham, MA 02453, USA., Walsh RT; X-Chem Inc., 100 Beaver Street, Waltham, MA 02453, USA., Hupp CD; X-Chem Inc., 100 Beaver Street, Waltham, MA 02453, USA. Electronic address: chupp@x-chemrx.com.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Nov 01; Vol. 51, pp. 128339. Date of Electronic Publication: 2021 Sep 01.
Autor:
Lee ECY; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., McRiner AJ; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Georgiadis KE; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Liu J; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Wang Z; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Ferguson AD; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Levin B; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., von Rechenberg M; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Hupp CD; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Monteiro MI; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Keefe AD; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Olszewski A; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Eyermann CJ; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Centrella P; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Liu Y; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Arora S; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Cuozzo JW; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Clark MA; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Huguet C; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Kohlmann A; X-Chem Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 May 27; Vol. 64 (10), pp. 6730-6744. Date of Electronic Publication: 2021 May 06.
Autor:
Veerman JJN; ZoBio BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands., Bruseker YB; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Damen E; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Heijne EH; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., van Bruggen W; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Hekking KFW; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Winkel R; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Hupp CD; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Keefe AD; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Liu J; Civetta Therapeutics, 10 Wilson Road, Cambridge, Massachusetts 02138, United States., Thomson HA; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Cuozzo JW; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., McRiner AJ; X-Chem, Inc., 100 Beaver Street, Waltham, Massachusetts 02453, United States., Mulvihill MJ; HiberCell Inc., New York, New York 10019, United States., van Rijnsbergen P; Mercachem BV, Department of Medicinal Chemistry, Kerkenbos 1013, 6546 BB Nijmegen, The Netherlands., Zech B; AnavoTherapeutics BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands., Renzetti LM; Bridge Medicines LLC, New York, New York 10017, United States., Babiss L; Wilmington, North Carolina 28405, United States., Müller G; AnavoTherapeutics BV, J.H. Oortweg 19, 2333 CH Leiden, The Netherlands.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Mar 03; Vol. 12 (4), pp. 555-562. Date of Electronic Publication: 2021 Mar 03 (Print Publication: 2021).
Autor:
Mimasu S; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan. shinya.mimasu@astellas.com., Yamagishi H; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan.; Electronic Materials Department, Idemitsu Kosan Co., Ltd., Sodegaura, Chiba, Japan., Kubo S; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan., Kiyohara M; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan., Matsuda T; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan., Yahata T; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan., Thomson HA; X-Chem Inc., Waltham, MA, USA., Hupp CD; X-Chem Inc., Waltham, MA, USA., Liu J; X-Chem Inc., Waltham, MA, USA.; Civetta Therapeutics, Cambridge, MA, USA., Okuda T; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan.; Formulation, Tsukuba Laboratory, Nemoto Science Co., Ltd, Joso-shi, Ibaraki, Japan., Kakefuda K; Drug Discovery Research, Astellas Pharma. Inc., Tsukuba, Ibaraki, Japan.
Publikováno v:
Communications biology [Commun Biol] 2021 Feb 04; Vol. 4 (1), pp. 159. Date of Electronic Publication: 2021 Feb 04.
Autor:
McCloskey K; Google Research Applied Science, Mountain View, California 94043, United States., Sigel EA; X-Chem, Waltham, Massachusetts 02453, United States., Kearnes S; Google Research Applied Science, Mountain View, California 94043, United States., Xue L; X-Chem, Waltham, Massachusetts 02453, United States., Tian X; X-Chem, Waltham, Massachusetts 02453, United States., Moccia D; X-Chem, Waltham, Massachusetts 02453, United States.; Cognitive Dataworks, Amesbury, Massachusetts 01913, United States., Gikunju D; X-Chem, Waltham, Massachusetts 02453, United States., Bazzaz S; X-Chem, Waltham, Massachusetts 02453, United States., Chan B; X-Chem, Waltham, Massachusetts 02453, United States., Clark MA; X-Chem, Waltham, Massachusetts 02453, United States., Cuozzo JW; X-Chem, Waltham, Massachusetts 02453, United States., Guié MA; X-Chem, Waltham, Massachusetts 02453, United States., Guilinger JP; X-Chem, Waltham, Massachusetts 02453, United States., Huguet C; X-Chem, Waltham, Massachusetts 02453, United States., Hupp CD; X-Chem, Waltham, Massachusetts 02453, United States., Keefe AD; X-Chem, Waltham, Massachusetts 02453, United States., Mulhern CJ; X-Chem, Waltham, Massachusetts 02453, United States., Zhang Y; X-Chem, Waltham, Massachusetts 02453, United States., Riley P; Google Research Applied Science, Mountain View, California 94043, United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Aug 27; Vol. 63 (16), pp. 8857-8866. Date of Electronic Publication: 2020 Jun 11.
Autor:
Cuozzo JW, Centrella PA, Gikunju D, Habeshian S, Hupp CD, Keefe AD, Sigel EA, Soutter HH, Thomson HA, Zhang Y, Clark MA
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2017 Dec 14; Vol. 18 (24), pp. 2441. Date of Electronic Publication: 2017 Nov 22.
Autor:
Cuozzo JW; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Centrella PA; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Gikunju D; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Habeshian S; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Hupp CD; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Keefe AD; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Sigel EA; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Soutter HH; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Thomson HA; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Zhang Y; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA., Clark MA; X-Chem Pharmaceuticals, 100 Beaver Street, Waltham, MA, 02453, USA.
Publikováno v:
Chembiochem : a European journal of chemical biology [Chembiochem] 2017 May 04; Vol. 18 (9), pp. 864-871. Date of Electronic Publication: 2017 Feb 08.