Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Huoshun Shi"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-13 (2024)
Abstract Background Aortic stenosis (AS) is a prevalent and serious valvular heart disease with a complex etiology involving genetic predispositions, lipid dysregulation, and inflammation. The specific roles of lipid and protein biomarkers in AS deve
Externí odkaz:
https://doaj.org/article/2aece87531c64da9b1fa90126ba01983
Autor:
Lebo Sun, Albert Jiarui Li, Zhaoyang Wang, Guodong Xu, Dawei Zheng, Huoshun Shi, Jian-Qing Gao, Xiajun Li, Linwen Zhu, Caimin Zhu, Hua Zhou, Ni Li, Guofeng Shao
Publikováno v:
Aging (Albany NY)
Valvular heart disease (VHD) is a common heart disease that affects blood flow. It usually requires heart surgery. Valvular heart disease complicated with pulmonary artery hypertension (VHD-PAH) may be lethal due to heart failure that results from in
Publikováno v:
Evidence-based complementary and alternative medicine : eCAM. 2022
Hsa-microRNA (has-miR)-133a inactivates the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway and suppresses the cell proliferation of myocardial fibroblasts by downregulation of the epidermal growth factor receptor (EGFR) expression. Bioinf
Autor:
Guofeng Shao, Hua Zhou, Hangjuan Lin, Ni Li, Jian-Qing Gao, Huoshun Shi, Lebo Sun, Dawei Zheng, Guodong Xu, Xiuying Zhu
Publikováno v:
Experimental and Therapeutic Medicine
DNA methylation is known to regulate the expression of numerous genes but its role in the pathogenesis of thoracic aortic dissection (TAD) has remained largely elusive. In the present study, the DNA methylome of patients with TAD was analyzed using a
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
We determined the role of microRNA (miR)-9 in regulating cisplatin chemoresistance in nonsmall cell lung cancer (NSCLC) cells. miR-9 and eukaryotic translation initiation factor 5A2 (eIF5A2) levels were examined by reverse transcription–quantitativ
Autor:
Dawei Zheng, Ni Li, Qingyun Zhou, Xiaoying Chen, Limin Xu, Guodong Xu, Shiwei Duan, Guofeng Shao, Jing Liu, Lebo Sun, Huoshun Shi
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to identify differentially methylated regions (DMRs) in patients with rheumatic heart disease and secondary pulmonary arterial hypertension (RHD-PAH). A genome-wide DNA methylation assay was performed between 6 patien
Autor:
Ni Li, Qinning Wang, Caimin Zhu, Huoshun Shi, Xiuying Zhu, Guodong Xu, Dawei Zheng, Lebo Sun, Guofeng Shao
Publikováno v:
Bioscience Reports
To investigate the contribution of brain natriuretic peptide (BNP) promoter DNA methylation to the risk of rheumatic heart disease (RHD) and the influence of warfarin anticoagulant therapy on BNP methylation levels for RHD patients after surgery. BNP
Autor:
Guodong, Xu, Guofeng, Shao, Qiaoling, Pan, Lebo, Sun, Dawei, Zheng, Minghui, Li, Ni, Li, Huoshun, Shi, Yiming, Ni
Publikováno v:
American journal of translational research. 9(2)
MicroRNAs (miRNAs) play a critical role in cancer development and progression. Bioinformatics analyses has identified eukaryotic translation initiation factor 5A2 (eIF5A2) as a target of miR-9. In this study, we attempted to determine whether miR-9 r
Autor:
Qingyun Zhou, Lebo Sun, Enchill KoJo Incoom, Guodong Xu, Dawei Zheng, Jianqing Zhou, Xiaoyan Huang, Sheng Zhao, Xi Yang, Ni Li, Jiangfang Lian, Huoshun Shi, Guofeng Shao, Xinbao Shi
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
This study compared microRNA (miRNA) expression profiles between rheumatic heart disease (RHD) patients and healthy controls to investigate their differential expression and help elucidate their mechanisms of action. Microarray analysis was used to m
Autor:
Lebo Sun, Xinbao Shi, Huoshun Shi, Xianning Zhang, Guodong Xu, Ni Li, Guofeng Shao, Hui Yu, Dawei Zheng, Qingyun Zhou
Publikováno v:
BMC Pulmonary Medicine
Background Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigen