Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Huoru Zhang"'
Autor:
Yong-Fei Wang, Yan Zhang, Zhiming Lin, Huoru Zhang, Ting-You Wang, Yujie Cao, David L. Morris, Yujun Sheng, Xianyong Yin, Shi-Long Zhong, Xiaoqiong Gu, Yao Lei, Jing He, Qi Wu, Jiangshan Jane Shen, Jing Yang, Tai-Hing Lam, Jia-Huang Lin, Zhi-Ming Mai, Mengbiao Guo, Yuanjia Tang, Yanhui Chen, Qin Song, Bo Ban, Chi Chiu Mok, Yong Cui, Liangjing Lu, Nan Shen, Pak C. Sham, Chak Sing Lau, David K. Smith, Timothy J. Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The presentation of systemic lupus erythematosus has been known to differ by ancestry, but the underlying genetic factors remain unclear. Here, the authors report ancestry-specific susceptibility loci and better risk prediction when using data from m
Externí odkaz:
https://doaj.org/article/783362c0f8c8422595f0ff721e5c39ef
Autor:
Feixia Zhang, Yong-Fei Wang, Yan Zhang, Zhiming Lin, Yujie Cao, Huoru Zhang, Zhong-Yi Liu, David L. Morris, Yujun Sheng, Yong Cui, Xuejun Zhang, Timothy J. Vyse, Yu Lung Lau, Wanling Yang, Yanhui Chen
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease. Despite the significant progress made in identifying susceptibility genes for SLE, the genetic architecture of the disease is far from being understood. In this study, we
Externí odkaz:
https://doaj.org/article/8343c43f2d414acb80b9cc0f9e8cbe7d
Autor:
Huoru Zhang, Yan Zhang, Yong-Fei Wang, David Morris, Nattiya Hirankarn, Yujun Sheng, Jiangshan Shen, Hai-Feng Pan, Jing Yang, Sen Yang, Yong Cui, Dong-Qing Ye, Timothy J. Vyse, Xuejun Zhang, Yu Lung Lau, Wanling Yang
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-8 (2018)
Abstract Background Systemic lupus erythematous (SLE) is a complex autoimmune disease with female predominance, particularly affecting those of childbearing age. We performed analysis of three genome-wide genotyping datasets of populations of both Ch
Externí odkaz:
https://doaj.org/article/4c2dc391f4fc4f9fba81ccb2a29f10c2
Autor:
Yujie Cao, Shau-yin Ha, Chi-Chiu So, Ming-for Tony Tong, Clara Sze-man Tang, Huoru Zhang, Rui Liang, Jing Yang, Brian Hon-Yin Chung, Godfrey Chi-Fung Chan, Yu Lung Lau, Maria-Mercè Garcia-Barcelo, Edmond Shiu-Kwan Ma, Pranee Sucharitchan, Nattiya Hirankarn, Wanling Yang
Publikováno v:
The Journal of Molecular Diagnostics. 24:1089-1099
Thalassemia is one of the most common genetic diseases and a major health threat worldwide. Accurate, efficient, and scalable analysis of next-generation sequencing (NGS) data is much needed for its molecular diagnosis and carrier screening. We devel
Autor:
Jing Yang, Yao Lei, Timothy J. Vyse, Tai Hing Lam, Pak C. Sham, Liangjing Lu, Yujun Sheng, Chak Sing Lau, Ting-You Wang, Yu-Lung Lau, Shi Long Zhong, Yujie Cao, Huoru Zhang, Mengbiao Guo, Wanling Yang, Bo Ban, Jia Huang Lin, David L. Morris, Yuanjia Tang, David K. Smith, Nan Shen, Qin Song, Yanhui Chen, Yong-Fei Wang, Jing He, Chi Chiu Mok, Zhiming Lin, Qi Wu, Xianyong Yin, Xuejun Zhang, Yong Cui, Yan Zhang, Jiangshan Jane Shen, Zhi Ming Mai, Xiaoqiong Gu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high heritability, shows differences in prevalence, severity and age of onset among different ancestral groups. Previous genetic studies have focused more on European populations
Autor:
Timothy J. Vyse, Yujun Sheng, Wanling Yang, Yujie Cao, Bo Ban, Yanhui Chen, Nan Shen, Jing He, Chak Sing Lau, Chi Chiu Mok, Qi Wu, David L. Morris, Zhi-Ming Mai, Xuejun Zhang, Xiaoqiong Gu, Qin Song, Yuanjia Tang, Yu-Lung Lau, Pak C. Sham, David K. Smith, Zhiming Lin, Huoru Zhang, Yong Cui, Liangjing Lu, Jing Yang, Yong-Fei Wang, Yao Lei, Yan Zhang, Jiangshan Jane Shen, Tai Hing Lam, Ting-You Wang, Jia-Huang Lin, Mengbiao Guo, Xianyong Yin, Shi-Long Zhong
Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high heritability, shows differences in prevalence, severity and age of onset among different ancestral groups. Previous genetic studies have focused more on European populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e70ec3ce24c0fa166c6467094c6801a
https://doi.org/10.1101/2020.04.12.037622
https://doi.org/10.1101/2020.04.12.037622
Autor:
Xuejun Zhang, Lingyan Chen, Deborah S. Cunninghame Graham, Wangling Yang, David L. Morris, Yong-Fei Wang, Lu Liu, Adrianna Bielowka, Phil Tombleson, Christopher A. Odhams, Rahell Ahmed, Huoru Zhang, Amy L. Roberts, Timothy J. Vyse
Publikováno v:
Chen, L, Wang, Y F, Liu, L, Bielowka, A, Ahmed, R, Zhang, H, Tombleson, P, Roberts, A L, Odhams, C A, Cunninghame Graham, D S, Zhang, X, Yang, W, Vyse, T J & Morris, D L 2020, ' Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity ', Human Molecular Genetics, vol. 29, no. 10, ddaa030, pp. 1745-1756 . https://doi.org/10.1093/hmg/ddaa030
Human Molecular Genetics
Human Molecular Genetics
ObjectiveUsing three European and two Chinese genome-wide association studies (GWAS), we investigated the performance of genetic risk scores (GRS) for predicting the susceptibility and severity of Systemic lupus erythematosus (SLE), using renal disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefcb199a1e215a418b77741f7f46f24
Autor:
Yong-Fei Wang, Yu-Lung Lau, Xuejun Zhang, Yan Zhang, Jing Yang, Yujun Sheng, Jiangshan Shen, Hai-Feng Pan, Sen Yang, Yong Cui, Huoru Zhang, Dong-Qing Ye, David L. Morris, Wanling Yang, Nattiya Hirankarn, Timothy J. Vyse
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-8 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy
Background Systemic lupus erythematous (SLE) is a complex autoimmune disease with female predominance, particularly affecting those of childbearing age. We performed analysis of three genome-wide genotyping datasets of populations of both Chinese and
Autor:
Yan Zhang, Jiangshan Jane Shen, Wanling Yang, David L. Morris, Yong Cui, Timothy J. Vyse, Yujun Sheng, Hai-Feng Pan, Dong-Qing Ye, Yu-Lung Lau, Zhengwei Zhu, Huoru Zhang, Jing Yang, Yong-Fei Wang, Sen Yang, Xuejun Zhang, Ting-You Wang
Publikováno v:
Annals of the Rheumatic Diseases. 77:1078-1084
ObjectivesSystemic lupus erythematosus (SLE) is a prototype autoimmune disease with a strong genetic component in its pathogenesis. Through genome-wide association studies (GWAS), we recently identified 10 novel loci associated with SLE and uncovered
Autor:
Yong-Fei, Wang, Yan, Zhang, Zhengwei, Zhu, Ting-You, Wang, David L, Morris, Jiangshan Jane, Shen, Huoru, Zhang, Hai-Feng, Pan, Jing, Yang, Sen, Yang, Dong-Qing, Ye, Timothy J, Vyse, Yong, Cui, Xuejun, Zhang, Yujun, Sheng, Yu Lung, Lau, Wanling, Yang
Publikováno v:
Annals of the rheumatic diseases. 77(7)
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with a strong genetic component in its pathogenesis. Through genome-wide association studies (GWAS), we recently identified 10 novel loci associated with SLE and uncovered a number