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pro vyhledávání: '"Huo-Mei Xiong"'
Autor:
Xi-Min Chen, Jing Li, Jing Liu, Xiao-Zhong Wang, Dan-Qin Feng, Huo-Mei Xiong, Bo Huang, Hai-Bin Zhang, Yun Xiao
Publikováno v:
Onkologie. 35:335-340
Background: Acute myeloid leukemia (AML) is the most common type of blood cancer in adults. Emerging evidence is establishing a connection between AML and aberrant alternative splicing of pre-mRNA, which may result from aberrant expression of splicin
Autor:
Huo-Mei Xiong, Hai-Bin Zhang, Jing-Jing Li, Bo Huang, Jing Liu, Xi-Min Chen, Yun Xiao, Xiao-Zhong Wang, Dan-Qin Feng
Publikováno v:
International Journal of Molecular Medicine
Imatinib is the therapeutic standard for newly diagnosed patients with chronic myeloid leukemia (CML). In these patients, imatinib has been shown to induce an apoptotic response specifically in cells expressing the oncogenic fusion protein BCR-ABL. P