Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hunter J. Melton"'
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Although DNA methylation (DNAm) has been implicated in the pathogenesis of numerous complex diseases, from cancer to cardiovascular disease to autoimmune disease, the exact methylation sites that play key roles in these processes remain elusive. One
Externí odkaz:
https://doaj.org/article/ce4c8e39384040168a51e23a5c1425e9
Autor:
Alexandra Melton, Lori A. Rowe, Toni Penney, Clara Krzykwa, Kelly Goff, Sarah E. Scheuermann, Hunter J. Melton, Kelsey Williams, Nadia Golden, Kristyn Moore Green, Brandon Smith, Kasi Russell-Lodrigue, Jason P. Dufour, Lara A. Doyle-Meyers, Faith Schiro, Pyone P. Aye, Jeffery D. Lifson, Brandon J. Beddingfield, Robert V. Blair, Rudolf P. Bohm, Jay K. Kolls, Jay Rappaport, James A. Hoxie, Nicholas J. Maness
Publikováno v:
Viruses, Vol 16, Iss 7, p 1173 (2024)
The effects of immunodeficiency associated with chronic HIV infection on COVID-19 disease and viral persistence have not been directly addressed in a controlled setting. In this pilot study, we exposed two pigtail macaques (PTMs) chronically infected
Externí odkaz:
https://doaj.org/article/6540d9832a1c4780aadcbb2a30855213
Autor:
Alexandra Melton, Lara A Doyle-Meyers, Robert V Blair, Cecily Midkiff, Hunter J Melton, Kasi Russell-Lodrigue, Pyone P Aye, Faith Schiro, Marissa Fahlberg, Dawn Szeltner, Skye Spencer, Brandon J Beddingfield, Kelly Goff, Nadia Golden, Toni Penney, Breanna Picou, Krystle Hensley, Kristin E Chandler, Jessica A Plante, Kenneth S Plante, Scott C Weaver, Chad J Roy, James A Hoxie, Hongmei Gao, David C Montefiori, Joseph L Mankowski, Rudolf P Bohm, Jay Rappaport, Nicholas J Maness
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010162 (2021)
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithf
Externí odkaz:
https://doaj.org/article/a4d62fa7ec5b4fcc9a46c16a5466b091
Publikováno v:
medRxiv
DNA methylation has been shown to be involved in the etiology of many complex diseases, yet the specific key underlying methylation sites remain largely unknown. One strategy to identify putative causal CpG sites and enhance disease etiology understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0304bf3b1ee4f921ae0701e305217a47
https://doi.org/10.1101/2023.03.20.23287418
https://doi.org/10.1101/2023.03.20.23287418
Publikováno v:
medRxiv
Transcriptome-wide association studies (TWAS) integrate gene expression prediction models and genome-wide association studies (GWAS) to identify gene–trait associations. The power of TWAS is determined by the sample size of GWAS and the accuracy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1089cdfb900c90f7049afd6fad2c8544
https://europepmc.org/articles/PMC9934719/
https://europepmc.org/articles/PMC9934719/
Autor:
Marissa Fahlberg, Cecily C. Midkiff, Hongmei Gao, Faith Schiro, Breanna Picou, Kasi E. Russell-Lodrigue, Pyone P. Aye, Kelly Goff, Krystle Hensley, Nadia A. Golden, Rudolf P. Bohm, David C. Montefiori, Lara A. Doyle-Meyers, Nicholas J. Maness, Robert V Blair, Scott C. Weaver, Joseph L. Mankowski, Alexandra Melton, Jay Rappaport, Brandon J. Beddingfield, Dawn M. Szeltner, Chad J. Roy, Kristin E Chandler, Skye Spencer, Toni Penney, Jessica A. Plante, James A. Hoxie, Hunter J Melton, Kenneth S. Plante
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010162 (2021)
PLoS Pathogens
PLoS Pathogens
The novel coronavirus SARS-CoV-2, the causative agent of COVID-19 disease, has killed over five million people worldwide as of December 2021 with infections rising again due to the emergence of highly transmissible variants. Animal models that faithf