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pro vyhledávání: '"Hunter J. Hill"'
Autor:
Hunter J. Hill, Kent G. Golic
Publikováno v:
Cells, Vol 11, Iss 22, p 3550 (2022)
It has been 70 years since the concept of varied centromere strengths was introduced based on the behavior of dicentric chromosomes. One of the key conclusions from those early experiments was that some centromeres could pull with sufficient force to
Externí odkaz:
https://doaj.org/article/a851144c14804b4ca2876ab7f2753e82
Publikováno v:
GENETICS. 224
Chromosome breakage plays an important role in the evolution of karyotypes and can produce deleterious effects within a single individual, such as aneuploidy or cancer. Forces that influence how and where chromosomes break are not fully understood. I