Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Hunter D. Reavis"'
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Akademický článek
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Autor: Kai Doberstein, Rebecca Spivak, Hunter D. Reavis, Jagmohan Hooda, Yi Feng, Paul T. Kroeger, Sarah Stuckelberger, Gordon B. Mills, Kyle M. Devins, Lauren E. Schwartz, Marcin P. Iwanicki, Mina Fogel, Peter Altevogt, Ronny Drapkin
Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
L1CAM is implicated as an important factor that enables early fallopian tube cancer precursors to seed the ovary by promoting cell survival through extracellular matrix signaling, thereby facilitating ovarian cancer growth.
Externí odkaz: https://doaj.org/article/72d15a5115e24cf6806f17c0c2a2f6ba
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6
Tumor Innervation: Cancer Has Some Nerve
Autor: Ronny Drapkin, Hunter D. Reavis, H. Isaac Chen
Publikováno v: Trends Cancer
Over the past decade, several landmark reports have demonstrated that the nervous system plays an active role in cancer initiation and progression. These studies demonstrate that ablation of specific nerve types (parasympathetic, sympathetic, or sens
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c06d3256ae6e48968950ff80bc67a35
https://doi.org/10.1016/j.trecan.2020.07.005
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7
MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
Autor: Hunter D. Reavis, Amy E. Schade, Larissa A. Sambel, David Kozono, Peter Deraska, Alan D. D'Andrea, Hembly G. Rivas, Timothy Branigan, James A. DeCaprio, Geoffrey I. Shapiro
Publikováno v: Cell reports
SUMMARY To identify genes whose loss confers resistance to CHK1 inhibitors, we perform genome-wide CRISPR-Cas9 screens in non-small-cell lung cancer (NSCLC) cell lines treated with the CHK1 inhibitor prexasertib (CHK1i). Five of the top six hits of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd636612286e0608790d69fa16f7218
https://pubmed.ncbi.nlm.nih.gov/33657372
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9
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Autor: Kai, Doberstein, Rebecca, Spivak, Hunter D, Reavis, Jagmohan, Hooda, Yi, Feng, Paul T, Kroeger, Sarah, Stuckelberger, Gordon B, Mills, Kyle M, Devins, Lauren E, Schwartz, Marcin P, Iwanicki, Mina, Fogel, Peter, Altevogt, Ronny, Drapkin
Publikováno v: Communications biology. 5(1)
Most ovarian high-grade serous carcinomas (HGSC) arise from Serous Tubal Intraepithelial Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC lesions from FT secretory cells leads to seeding of the ovarian surface,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21f8b8758d2ff4085e4894f434225752
https://pubmed.ncbi.nlm.nih.gov/36509990
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10
Abstract PR006: Infiltration of TRPV1+ nerves influences the ovarian cancer immune landscape
Autor: Hunter D. Reavis, Ronny Drapkin, Paola D. Vermeer, Daniel W. Vermeer, Allison Kruse, Matthew Knarr, Anthony C. Restaino
Publikováno v: Cancer Research. 81:PR006-PR006
High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecological malignancy, with poor survival rates attributable to both late diagnosis and resistance of tumors to standard-of-care chemotherapies. Recent therapeutic strategies aim to cir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90b57ce6615cfafc3565f61dcbd1b726
https://doi.org/10.1158/1538-7445.tme21-pr006
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