Glycine homeostasis requires reverse SHMT flux

Autor: McBride, Matthew J., Hunter, Craig J., Zhang, Zhaoyue, TeSlaa, Tara, Xu, Xincheng, Ducker, Gregory S., Rabinowitz, Joshua D.

Publikováno v: In Cell Metabolism 2 January 2024 36(1):103-115

Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation in Muscle.

Autor: Mann CG; Department of Health Sciences and Technology, ETH Zurich, Zurich 8092, Switzerland., MacArthur MR; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544, USA., Zhang J; Department of Health Sciences and Technology, ETH Zurich, Zurich 8092, Switzerland., Gong S; Department of Health Sciences and Technology, ETH Zurich, Zurich 8092, Switzerland., AbuSalim JE; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544, USA.; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Hunter CJ; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544, USA., Lu W; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA., Agius T; Department of Vascular Surgery, Lausanne University Hospital (CHUV), Lausanne 1005, Switzerland., Longchamp A; Department of Vascular Surgery, Lausanne University Hospital (CHUV), Lausanne 1005, Switzerland.; Transplant Center, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; Center for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Allagnat F; Department of Vascular Surgery, Lausanne University Hospital (CHUV), Lausanne 1005, Switzerland., Rabinowitz J; Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544, USA.; Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA., Mitchell JR; Department of Health Sciences and Technology, ETH Zurich, Zurich 8092, Switzerland.; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., De Bock K; Department of Health Sciences and Technology, ETH Zurich, Zurich 8092, Switzerland., Mitchell SJ; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ 08544, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jul 01. Date of Electronic Publication: 2024 Jul 01.