Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models.

Autor: McConnell EM; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Chan D; Department of Neuroscience, Carleton University, Ottawa, ON K1S 5B6, Canada., Ventura K; Department of Neuroscience, Carleton University, Ottawa, ON K1S 5B6, Canada., Callahan JP; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Harris K; Department of Neuroscience, Carleton University, Ottawa, ON K1S 5B6, Canada., Hunt VH; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Boisjoli S; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Knight D; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Monk ET; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada., Holahan MR; Department of Neuroscience, Carleton University, Ottawa, ON K1S 5B6, Canada., DeRosa MC; Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.; Institute of Biochemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.

Publikováno v: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2024 Jun 15; Vol. 35 (3), pp. 102251. Date of Electronic Publication: 2024 Jun 15 (Print Publication: 2024).