Zobrazeno 1 - 10 of 258 pro vyhledávání: '"Hunt Ca"'
1
Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-Regulation
Autor: Hunt, C. Anthony, Petersen, BK, Ropella, GEP, Hunt, CA
Publikováno v: Hunt, C. Anthony; Petersen, BK; Ropella, GEP; & Hunt, CA. (2016). Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-Regulation. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/2gb0z030
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::36915e32fbb7619184e18ea311540cc8
http://www.escholarship.org/uc/item/2gb0z030
Zobrazit plný text záznamu
2
Utility of Next-generation sequencing in Managing Bacterial Vaginosis: Examples from Clinical Practice
Autor: John Woody, Parker Lr, Daniel Mcdyer, Bostwick Gd, William T. Budd, Hunt Ca
Publikováno v: Journal of Women's Health Care. 5
There is an unacceptably high recurrence rate for bacterial vaginosis and vaginitis owing to multiple causes, including misdiagnosis and empirical under-treatment and over-treatment. A diagnostic test that provided complete knowledge of the vaginal m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2a9d873d80c23f97e88576c06d8b970
https://doi.org/10.4172/2167-0420.1000322
Zobrazit plný text záznamu
3
In silico, experimental, mechanistic model for extended-release felodipine disposition exhibiting complex absorption and a highly variable food interaction
Autor: Hunt, C. Anthony, Kim, SHJ, Jackson, AJ, Hunt, CA
Publikováno v: Hunt, C. Anthony; Kim, SHJ; Jackson, AJ; & Hunt, CA. (2014). In silico, experimental, mechanistic model for extended-release felodipine disposition exhibiting complex absorption and a highly variable food interaction. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/3xq0377q
The objective of this study was to develop and explore new, in silico experimental methods for deciphering complex, highly variable absorption and food interaction pharmacokinetics observed for a modified-release drug product. Toward that aim, we con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::1a342ecb472cdf0b11984ec56a50e398
http://www.escholarship.org/uc/item/3xq0377q
Zobrazit plný text záznamu
4
Toward modular biological models: Defining analog modules based on referent physiological mechanisms
Autor: Hunt, C. Anthony, Petersen, BK, Ropella, GEP, Hunt, CA
Publikováno v: Hunt, C. Anthony; Petersen, BK; Ropella, GEP; & Hunt, CA. (2014). Toward modular biological models: Defining analog modules based on referent physiological mechanisms. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/8v12c990
© 2014 Petersen et al.; licensee BioMed Central Ltd.Background: Currently, most biomedical models exist in isolation. It is often difficult to reuse or integrate models or their components, in part because they are not modular. Modular components al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::c95223bc604c9b97e4b2154c2a659ec7
http://www.escholarship.org/uc/item/8v12c990
Zobrazit plný text záznamu
5
Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models
Autor: Hunt, C. Anthony, Kirschner, DE, Hunt, CA, Marino, S, Fallahi-Sichani, M, Linderman, JJ
Publikováno v: Hunt, C. Anthony; Kirschner, DE; Hunt, CA; Marino, S; Fallahi-Sichani, M; & Linderman, JJ. (2014). Tuneable resolution as a systems biology approach for multi-scale, multi-compartment computational models. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6v72q65k
The use of multi-scale mathematical and computational models to study complex biological processes is becoming increasingly productive. Multi-scale models span a range of spatial and/or temporal scales and can encompass multi-compartment (e.g., multi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::f1194152afe9c065ee04ce321e375ea5
http://www.escholarship.org/uc/item/6v72q65k
Zobrazit plný text záznamu
6
Agent-based modeling: A systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity
Autor: Hunt, C. Anthony, Hunt, CA, Kennedy, RC, Kim, SHJ, Ropella, GEP
Publikováno v: Hunt, C. Anthony; Hunt, CA; Kennedy, RC; Kim, SHJ; & Ropella, GEP. (2013). Agent-based modeling: A systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/0sm20216
A crisis continues to brew within the pharmaceutical research and development (R&D) enterprise: productivity continues declining as costs rise, despite ongoing, often dramatic scientific and technical advances. To reverse this trend, we offer various
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::9978d8826cd99d9cf41512e0aa87ff9b
http://www.escholarship.org/uc/item/0sm20216
Zobrazit plný text záznamu
7
Individualized, discrete event, simulations provide insight into inter- and intra-subject variability of extended-release, drug products
Autor: Hunt, C. Anthony, Kim, SHJ, Jackson, AJ, Hur, R, Hunt, CA
Publikováno v: Hunt, C. Anthony; Kim, SHJ; Jackson, AJ; Hur, R; & Hunt, CA. (2012). Individualized, discrete event, simulations provide insight into inter-and intra-subject variability of extended-release, drug products. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1jc6j5nw
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::09a626bcee6a305dbfaeea3a4ec9ef47
http://www.escholarship.org/uc/item/1jc6j5nw
Zobrazit plný text záznamu
10
Inhibition of transcription factor binding to the HER2 promoter by triplex-forming oligodeoxyribonucleotides
Autor: Christopher C. Benz, Hogan Me, Gary K. Scott, Hunt Ca, Sarah B. Noonberg
Publikováno v: Gene. 149(1)
We have identified a 28-bp homopurine/homopyrimidine sequence capable of triple helix (triplex) formation with G+T-rich oligodeoxyribonucleotides (oligos) within the critical proximal promoter of the HER2/neu/c-erbB2 (HER2) proto-oncogene. To investi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1804f59dd1fec898530efe961311f5b
https://pubmed.ncbi.nlm.nih.gov/7958975
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje