Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Hunjoo Ha"'
Autor:
Songling Jiang, Md Jamal Uddin, Xiaoying Yu, Lingjuan Piao, Debra Dorotea, Goo Taeg Oh, Hunjoo Ha
Publikováno v:
Diabetes & Metabolism Journal, Vol 46, Iss 6, Pp 829-842 (2022)
Background Non-alcoholic fatty liver disease (NAFLD) has been increasing in association with the epidemic of obesity and diabetes. Peroxisomes are single membrane-enclosed organelles that play a role in the metabolism of lipid and reactive oxygen spe
Externí odkaz:
https://doaj.org/article/0676a59207724b0da6ac16d13faa61b3
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/7441120922664caa9f9055b0cb6b6a12
Publikováno v:
Kidney Research and Clinical Practice, Vol 41, Iss Suppl 2, Pp S74-S88 (2022)
Diabetic kidney disease (DKD) is now a pandemic worldwide, and novel therapeutic options are urgently required. Adenosine, an adenosine triphosphate metabolite, plays a role in kidney homeostasis through interacting with four types of adenosine recep
Externí odkaz:
https://doaj.org/article/ca8ef4fb91844615a47348b84b6bda45
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Sterol regulatory-element binding proteins (SREBPs) are classical regulators of cellular lipid metabolism in the kidney and other tissues. SREBPs are currently recognized as versatile transcription factors involved in a myriad of cellular processes.
Externí odkaz:
https://doaj.org/article/05da98b64d784448b0731a167dc3880f
Autor:
Debra Dorotea, Ahreum Cho, Gayoung Lee, Guideock Kwon, Junghwa Lee, Pramod K. Sahu, Lak Shin Jeong, Dae Ryong Cha, Hunjoo Ha
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-14 (2018)
Diabetic kidney disease: drug successfully targets key protein A therapeutic treatment targeting a protein involved in the progression of diabetic kidney disease (DKD) shows promise in mouse trials. Between 30 and 40 per cent of diabetic patients suf
Externí odkaz:
https://doaj.org/article/13a6e955e2c042ca9f5e8bdd1b6b6af2
Autor:
Weiwei Zhu, Namood E Sahar, Hafiz Muhammad Ahmad Javaid, Eun Seon Pak, Guang Liang, Yi Wang, Hunjoo Ha, Joo Young Huh
Publikováno v:
Cells, Vol 10, Iss 12, p 3306 (2021)
Non-alcoholic fatty liver disease (NAFLD) is a global clinical problem. The MD2-TLR4 pathway exacerbates NAFLD progression by promoting inflammation. Long-term exercise is considered to improve NAFLD but the underlying mechanism is still unclear. In
Externí odkaz:
https://doaj.org/article/72948fe9874b44a18ece0156762b6e01
Autor:
Md. Ataur Rahman, Raju Dash, Abdullah Al Mamun Sohag, Mahboob Alam, Hyewhon Rhim, Hunjoo Ha, Il Soo Moon, Md Jamal Uddin, Md. Abdul Hannan
Publikováno v:
Marine Drugs, Vol 19, Iss 3, p 167 (2021)
Alzheimer’s disease (AD) is a degenerative brain disorder characterized by a progressive decline in memory and cognition, mostly affecting the elderly. Numerous functional bioactives have been reported in marine organisms, and anti-Alzheimer’s ag
Externí odkaz:
https://doaj.org/article/f335ec5c6ce44699ba12271f49da47d5
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 258 (2021)
The global burden of chronic kidney disease (CKD) intertwined with cardiovascular disease has become a major health problem. Oxidative stress (OS) plays an important role in the pathophysiology of CKD. The nuclear factor erythroid 2-related factor 2
Externí odkaz:
https://doaj.org/article/052381c26def48a284a2ce985fa297a5
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 322 (2021)
Irisin is an exercise-induced myokine, suggested to exert beneficial effects on metabolism. However, the studies on the regulation of irisin secretion and the expression of its precursor FNDC5 have shown conflicting data. The discrepancies among prev
Externí odkaz:
https://doaj.org/article/c9654bd25ab246e1a08495b55ea43abd
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Macrophages are important components of adipose tissue inflammation, which results in metabolic diseases such as insulin resistance. Notably, obesity induces a proinflammatory phenotypic switch in adipose tissue macrophages, and oxidative stress faci
Externí odkaz:
https://doaj.org/article/59c79c8776b240ebabe0720dfba21fe3