Zobrazeno 1 - 10
of 247
pro vyhledávání: '"Hung-Jen Chen"'
Autor:
Hsu-Yuan Chen, Chia-Hung Chen, Wei-Chih Liao, Yu-Chao Lin, Hung-Jen Chen, Te-Chun Hsia, Wen-Chien Cheng, Chih-Yen Tu
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Osimertinib is an irreversible third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). It is the preferred first-line treatment for EGFR-mutated non-small cell lung cancer (NSCLC) compared to firs
Externí odkaz:
https://doaj.org/article/6c9feeed91984718bc84979f42eb8c99
Autor:
Hung‐Jen Chen, Wen‐Chien Cheng, Chih‐Yen Tu, Te‐Chun Hsia, Yu‐Sen Lin, Hsin‐Yuan Fang, Chia‐Chin Li, Chun‐Ru Chien
Publikováno v:
Thoracic Cancer, Vol 15, Iss 24, Pp 1779-1791 (2024)
Abstract Introduction The use of stereotactic ablative radiotherapy (SABR) over conventional fractionated radiotherapy (CFRT) for early‐stage non‐small‐cell lung cancer (NSCLC) has been advocated, but is also debated in the literature. Methods
Externí odkaz:
https://doaj.org/article/b5a1df5980e245789315c493f66a336b
Autor:
Hung-Jen Chen, Daniel C. Sévin, Guillermo R. Griffith, Johanna Vappiani, Lee M. Booty, Cindy P.A.A. van Roomen, Johan Kuiper, Jeroen den Dunnen, Wouter J. de Jonge, Rab K. Prinjha, Palwinder K. Mander, Paola Grandi, Beata S. Wyspianska, Menno P.J. de Winther
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114741- (2024)
Summary: Macrophages exhibit diverse phenotypes and respond flexibly to environmental cues through metabolic remodeling. In this study, we present a comprehensive multi-omics dataset integrating intra- and extracellular metabolomes with transcriptomi
Externí odkaz:
https://doaj.org/article/ae89bd3f7a5c4e6f9f0d1640e1046c34
Autor:
Wen-Chien Cheng, Chi-Chien Lin, Wei-Chih Liao, Yu-Chao Lin, Chia-Hung Chen, Hung-Jen Chen, Chih-Yen Tu, Te-Chun Hsia
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Objectives The irreversible epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) afatinib and dacomitinib are approved for first-line treatment of EGFR mutation-positive non-small cell lung cancer (NSCLC). We aimed to comp
Externí odkaz:
https://doaj.org/article/d39ef3124fc64d44bd1141cb823d8225
Autor:
Wei‐Chun Chen, Wen‐Chien Cheng, Chieh‐Lung Chen, Wei‐Chih Liao, Chia‐Hung Chen, Hung‐Jen Chen, Chih‐Yen Tu, Chi‐Chen Lin, Te‐Chun Hsia
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Background This study aimed to examine the clinical characteristics of bone metastasis (BoM) in patients with non‐small cell lung cancer (NSCLC) who have an epidermal growth factor receptor (EGFR) mutation and to identify the most effectiv
Externí odkaz:
https://doaj.org/article/bb2d95e0862942759be2f35dbd3c2237
Autor:
Chieh-Lung Chen, Sing-Ting Wang, Wei-Chih Liao, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia, Wen-Chien Cheng, Hung-Jen Chen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background The patient population with stage III non-small-cell lung cancer (NSCLC) is heterogeneous, with varying staging characteristics and diverse treatment options. Despite the potential practice-changing implications of randomized cont
Externí odkaz:
https://doaj.org/article/e3287c0494444d8d86120f3fa55815dc
Autor:
Satoshi Nozuma, Akiko Yoshimura, Shun-Chung Pai, Hung-Jen Chen, Eiji Matsuura, Masakazu Tanaka, Daisuke Kodama, Mika Dozono, Toshio Matsuzaki, Hiroshi Takashima, Ya-Chien Yang, Ryuji Kubota
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011928 (2024)
BackgroundAlthough Japan is a major endemic area for human T-lymphotropic virus type 1 (HTLV-1) and the virus has been well-studied in this region, there is limited research on HTLV-1 in surrounding regions. In this study, we determined the complete
Externí odkaz:
https://doaj.org/article/2ce83ec0c5634d589081b6943a0c0900
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract The development of valid, reliable, and objective methods of skills assessment is central to modern surgical training. Numerous rating scales have been developed and validated for quantifying surgical performance. However, many of these scor
Externí odkaz:
https://doaj.org/article/84047b27c4b94839a95a976ef5aa8864
Autor:
Kuo‐Yang Huang, Hung‐Jen Chen, Ching‐Hsiung Lin, Bing‐Yen Wang, Ching‐Yuan Cheng, Sheng‐Hao Lin
Publikováno v:
Thoracic Cancer, Vol 13, Iss 13, Pp 1933-1939 (2022)
Abstract Background Identifying patients with stage I non‐small cell lung cancer (NSCLC) at increased risk of tumor recurrence following surgery remains a major challenge. The current study aimed to compare disease‐free survival (DFS) rates after
Externí odkaz:
https://doaj.org/article/d2ee2f7e1b7642e1b9323827a84e6126
Autor:
Lynn Mes, Ulrike Steffen, Hung-Jen Chen, Jennifer Veth, Willianne Hoepel, Guillermo Romeo Griffith, Georg Schett, Jeroen den Dunnen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
While immunoglobulin A (IgA) is well known for its neutralizing and anti-inflammatory function, it is becoming increasingly clear that IgA can also induce human inflammatory responses by various different immune cells. Yet, little is known about the
Externí odkaz:
https://doaj.org/article/fe44f0c0986b415ba53a6d2472558da3