Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Hung Ming Lam"'
Autor:
Rui M. Gil da Costa, Christine Levesque, Daniella Bianchi‐Frias, Payel Chatterjee, Hung‐Ming Lam, Carlos Santos, Ilsa M. Coleman, Pedro Ferreirinha, Manuel Vilanova, Nazaré Pinto da Cunha, Hugo Carvalho, Alexandra Moreira‐Pais, Ana Faustino‐Rocha, Tiago Neto, José Batista da Costa, Jonathan L. Wright, Rita Ferreira, Paula A. Oliveira, Joaquim Mendes, Margarida M. S. M. Bastos, Bruno Colaço, Carlos Lopes, Peter C. Black, Christopher J. Sweeney, Peter S. Nelson
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2709-2727 (2023)
Most patients with muscle‐invasive bladder cancer (MIBC) are not cured with platinum chemotherapy. Up‐regulation of nuclear factor kappa light‐chain enhancer of activated B cells (NF‐κB) is a major mechanism underlying chemoresistance, sugge
Externí odkaz:
https://doaj.org/article/c67189174a934005bc879e99ac388170
Autor:
Pornour, Majid, Hee-Young Jeon, Hyunju Ryu, Khadka, Sudeep, Rui Xu, Hegang Chen, Hussain, Arif, Hung-Ming Lam, Zhihao Zhuang, Htoo Zarni Oo, Gleave, Martin, Xuesen Dong, Qianben Wang, Barbieri, Christopher, Jianfei Qi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/30/2024, Vol. 121 Issue 31, p1-12, 258p
Autor:
Elise Y. Cai, Jose Garcia, Yuzhen Liu, Funda Vakar-Lopez, Sonali Arora, Holly M. Nguyen, Bryce Lakely, Lisha Brown, Alicia Wong, Bruce Montgomery, John K. Lee, Eva Corey, Jonathan L. Wright, Andrew C. Hsieh, Hung-Ming Lam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Bladder cancer is among the most prevalent cancers worldwide. Currently, few bladder cancer models have undergone thorough characterization to assess their fidelity to patient tumors, especially upon propagation in the laboratory. Here, we e
Externí odkaz:
https://doaj.org/article/5b9f2e7e7f544668b01d526be6457f1a
Autor:
Dimitrios Makrakis, Jonathan L. Wright, Martine P. Roudier, Jose Garcia, Funda Vakar-Lopez, Michael P. Porter, Yan Wang, Atreya Dash, Daniel Lin, George Schade, Brian Winters, Xiotun Zhang, Peter Nelson, Elahe Mostaghel, Heather H. Cheng, Michael Schweizer, Sarah K. Holt, John L. Gore, Evan Y. Yu, Hung Ming Lam, Bruce Montgomery
Publikováno v:
Clinical Genitourinary Cancer. 21:265-272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e8d4c8c24d4e9511cd699acda86499
https://doi.org/10.1016/j.clgc.2022.12.003
https://doi.org/10.1016/j.clgc.2022.12.003
Autor:
Sujata Jana, Rucha Deo, Rowan P. Hough, Yuzhen Liu, Jessie L. Horn, Jonathan L. Wright, Hung-Ming Lam, Kevin R. Webster, Gary G. Chiang, Nahum Sonenberg, Andrew C. Hsieh
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Using genetically engineered mouse models, this work demonstrates that protein synthesis is essential for efficient urothelial cancer formation and growth but dispensable for bladder homeostasis. Through a candidate gene analysis for translation regu
Externí odkaz:
https://doaj.org/article/2f23ca10819f4654a2a0748a88d95c63
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/9300136ac3844c8bb69bfbb05641dd7a
Autor:
Sen Zhu, Dongyu Zhao, Lin Yan, Weihua Jiang, Jung-Sun Kim, Bingnan Gu, Qipeng Liu, Rui Wang, Bo Xia, Jonathan C. Zhao, Gang Song, Wenyi Mi, Rong-Fu Wang, Xiaobing Shi, Hung-Ming Lam, Xuesen Dong, Jindan Yu, Kaifu Chen, Qi Cao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The polycomb group protein BMI1 is highly expressed in prostate cancer. Here, the authors demonstrate that BMI1 directly interacts with AR leading to increased AR signaling independently of PRC1 complex and that targeting BMI1 inhibits tumor growth o
Externí odkaz:
https://doaj.org/article/2c11102c772b403f8c968a42953aed26
Autor:
Fady Ghali, Funda Vakar-Lopez, Martine P. Roudier, Jose Garcia, Sonali Arora, Heather H. Cheng, Michael T. Schweizer, Michael Haffner, John K. Lee, Evan Y. Yu, Petros Grivas, Bruce Montgomery, Andrew C. Hsieh, Jonathan L. Wright, Hung-Ming Lam
Publikováno v:
Clinical Genitourinary Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df42f3c83a1284222d65d50e0f74959c
https://doi.org/10.1016/j.clgc.2023.05.014
https://doi.org/10.1016/j.clgc.2023.05.014
Autor:
Shan Li, Alicia Wong, Huiyun Sun, Vipul Bhatia, Gerardo Javier, Sujata Jana, Robert B. Montgomery, Jonathan L. Wright, Hung-Ming Lam, Andrew C. Hsieh, Bishoy M. Faltas, Michael C. Haffner, John K. Lee
Available genetically-defined cancer models are limited in genotypic and phenotypic complexity and underrepresent the heterogeneity of human cancer. Herein, we describe a combinatorial genetic strategy applied to an organoid transformation assay to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebcf9df82dac7782797526cef8aa34f6
https://doi.org/10.1101/2023.04.12.536652
https://doi.org/10.1101/2023.04.12.536652
Autor:
Yu-Cheng Lee, Hung-Ming Lam, Charles Rosser, Dan Theodorescu, William C. Parks, Keith Syson Chan
Publikováno v:
Nat Rev Urol
Bladder cancer is a prevalent but currently understudied cancer type and patient outcomes are poor when it progresses to the muscle-invasive stage. Current research in bladder cancer focuses on the genetic and epigenetic alterations occurring within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6646dcb3ea9d9065893a87a971f200f7
https://doi.org/10.1038/s41585-022-00608-y
https://doi.org/10.1038/s41585-022-00608-y