Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Hung Chang Chen"'
Autor:
Hung-Chang Chen, Nico Mueller, Katherine Stott, Chrysa Kapeni, Eilidh Rivers, Carolin M Sauer, Flavio Beke, Stephen J Walsh, Nicola Ashman, Louise O’Brien, Amir Rafati Fard, Arman Ghodsinia, Changtai Li, Fadwa Joud, Olivier Giger, Inti Zlobec, Ioana Olan, Sarah J Aitken, Matthew Hoare, Richard Mair, Eva Serrao, James D Brenton, Alicia Garcia-Gimenez, Simon E Richardson, Brian Huntly, David R Spring, Mikkel-Ole Skjoedt, Karsten Skjødt, Marc de la Roche, Maike de la Roche
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2233-2261 (2024)
Abstract We have developed and validated a highly specific, versatile antibody to the extracellular domain of human LGR5 (α-LGR5). α-LGR5 detects LGR5 overexpression in >90% of colorectal cancer (CRC), hepatocellular carcinoma (HCC) and pre-B-ALL t
Externí odkaz:
https://doaj.org/article/4df981d9b6cb481e9115536caaf2c410
Autor:
John S. Schardt, Even Walseng, Kim Le, Chunning Yang, Pooja Shah, Ying Fu, Kausar Alam, Cathryn R. Kelton, Yu Gu, Fengying Huang, Jia Lin, Wenhai Liu, Andrew Dippel, Hanzhi Zhang, Kathy Mulgrew, Stacy Pryts, Vijaykumar Chennupati, Hung-Chang Chen, Jessica Denham, Xiaoru Chen, Pallab Pradhan, Yuling Wu, Colin Hardman, Chihao Zhao, Michael Kierny, Yang Song, Simon J. Dovedi, Saso Cemerski, Yariv Mazor
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
T cell engagers (TCEs) are becoming an integral class of biological therapeutic owing to their highly potent ability to eradicate cancer cells. Nevertheless, the widespread utility of classical CD3-targeted TCEs has been limited by narrow therapeutic
Externí odkaz:
https://doaj.org/article/60b9a30240a24440876eea62946b972e
Autor:
Maximillian A. Robinson, Alan Kennedy, Carolina T. Orozco, Hung-Chang Chen, Erin Waters, Dalisay Giovacchini, Kay Yeung, Lily Filer, Claudia Hinze, Christopher Lloyd, Simon J. Dovedi, David M. Sansom
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114768- (2024)
Summary: The CTLA-4 and PD-1 checkpoints control immune responses and are key targets in immunotherapy. Both pathways are connected via a cis interaction between CD80 and PD-L1, the ligands for CTLA-4 and PD-1, respectively. This cis interaction prev
Externí odkaz:
https://doaj.org/article/bd659b5fd6cd460e8b103ac0c7d928f7
Publikováno v:
The Journal of Clinical Hypertension, Vol 25, Iss 10, Pp 951-956 (2023)
Abstract Elevated triglyceride glucose (TyG) index is associated with an increased risk of cardiovascular disease. The current study aimed to investigate whether the TyG index was correlated with renal function decline in patients with hypertension.
Externí odkaz:
https://doaj.org/article/c6fb2955912848c5bb53a04835a4ac08
Autor:
Hung-Chang Chen, Nico Mueller, Katherine Stott, Chrysa Kapeni, Eilidh Rivers, Carolin M Sauer, Flavio Beke, Stephen J Walsh, Nicola Ashman, Louise O’Brien, Amir Rafati Fard, Arman Ghodsinia, Changtai Li, Fadwa Joud, Olivier Giger, Inti Zlobec, Ioana Olan, Sarah J Aitken, Matthew Hoare, Richard Mair, Eva Serrao, James D Brenton, Alicia Garcia-Gimenez, Simon E Richardson, Brian Huntly, David R Spring, Mikkel-Ole Skjoedt, Karsten Skjødt, Marc de la Roche, Maike de la Roche
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 11, Pp 3026-3026 (2024)
Externí odkaz:
https://doaj.org/article/de85458260f0462188f26c6b70c4d232
Autor:
Yi-Chang Chen, Yuan-Yao Tsai, Sheng-Chi Chang, Hung-Chang Chen, Tao-Wei Ke, Abe Fingerhut, William Tzu-Liang Chen
Publikováno v:
World Journal of Emergency Surgery, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Introduction Laparoscopic colectomy is rarely performed for ischemic colitis. The aim of this propensity score-matched study was to compare preoperative characteristics, intraoperative details and short-term outcomes for emergent laparoscopi
Externí odkaz:
https://doaj.org/article/edcedb06eadd48e1813944db40f00d38
Autor:
Joachim Hanna, Flavio Beke, Louise M. O’Brien, Chrysa Kapeni, Hung-Chang Chen, Valentina Carbonaro, Alexander B. Kim, Kamal Kishore, Timon E. Adolph, Mikkel-Ole Skjoedt, Karsten Skjoedt, Marc de la Roche, Maike de la Roche
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Th17 cells are critical players in the immunopathology of a range of autoimmune diseases. Here the authors implicate Hedgehog signaling in Th17 polarization and in the immunopathology of intestinal inflammation in murine models and suggest therapeuti
Externí odkaz:
https://doaj.org/article/37d7f063bb4e46ea82ad72c1a4b36302
Autor:
Hung Chang Chen, 陳泓璋
103
Dry eye syndrome (DES) is one of the most common ocular disease in the world. In this study, it is going to discuss how to treat dry eye syndrome more efficiently. Artificial tear is the most common eye-drop to treat DES, but usually with pr
Dry eye syndrome (DES) is one of the most common ocular disease in the world. In this study, it is going to discuss how to treat dry eye syndrome more efficiently. Artificial tear is the most common eye-drop to treat DES, but usually with pr
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/6fxshk
Autor:
HUNG CHANG CHEN, 陳鴻琩
102
A LiFePo4 battery charge and discharge test system is developed in this project for estimating the state of charge. The system integrated current sensor ACS759, battery pack monitor LTC6803, DSP TMS320F28335, and human interface software Lab
A LiFePo4 battery charge and discharge test system is developed in this project for estimating the state of charge. The system integrated current sensor ACS759, battery pack monitor LTC6803, DSP TMS320F28335, and human interface software Lab
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/48537744413586739271
Autor:
Cheng-Jeng Tai, Tzu-Cheng Su, Ming-Chung Jiang, Hung-Chang Chen, Shing-Chuan Shen, Woan-Ruoh Lee, Ching-Fong Liao, Ying-Chun Chen, Shu-Hui Lin, Li-Tzu Li, Ko-Hung Shen, Chung-Min Yeh, Kun-Tu Yeh, Ching-Hsiao Lee, Hsin-Yi Shih, Chun-Chao Chang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/4f9a8408b2884074a00cdba42b0b533c