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pVACview: an interactive visualization tool for efficient neoantigen prioritization and selection

Autor: Xia, Huiming, Hoang, My, Schmidt, Evelyn, Kiwala, Susanna, McMichael, Joshua, Skidmore, Zachary L., Fisk, Bryan, Song, Jonathan J., Hundal, Jasreet, Mooney, Thomas, Walker, Jason R., Goedegebuure, S. Peter, Miller, Christopher A., Gillanders, William E., Griffith, Obi L., Griffith, Malachi

Neoantigen targeting therapies including personalized vaccines have shown promise in the treatment of cancers. Accurate identification/prioritization of neoantigens is highly relevant to designing clinical trials, predicting treatment response, and u

Externí odkaz: http://arxiv.org/abs/2406.06985

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pVACview: an interactive visualization tool for efficient neoantigen prioritization and selection

Autor: Huiming Xia, My H. Hoang, Evelyn Schmidt, Susanna Kiwala, Joshua McMichael, Zachary L. Skidmore, Bryan Fisk, Jonathan J. Song, Jasreet Hundal, Thomas Mooney, Jason R. Walker, S. Peter Goedegebuure, Christopher A. Miller, William E. Gillanders, Obi L. Griffith, Malachi Griffith

Publikováno v: Genome Medicine, Vol 16, Iss 1, Pp 1-12 (2024)

Abstract Background Neoantigen-targeting therapies including personalized vaccines have shown promise in the treatment of cancers, particularly when used in combination with checkpoint blockade therapy. At least 100 clinical trials involving these th

Externí odkaz: https://doaj.org/article/01d72c65e37e4a128cc544c775252cbb

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Solid cancer-directed CAR T cell therapy that attacks both tumor and immunosuppressive cells via targeting PD-L1

Autor: Yan Luo, Martha E. Gadd, Yaqing Qie, Andrea Otamendi-Lopez, Jesus E. Sanchez-Garavito, Mieu M. Brooks, Maria J. Ulloa Navas, Tanya Hundal, Shuhua Li, Vanessa K. Jones, Yanyan Lou, Tushar Patel, Roxana Dronca, Mohamed A. Kharfan-Dabaja, Haidong Dong, Alfredo Quinones-Hinojosa, Hong Qin

Publikováno v: Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200891- (2024)

Chimeric antigen receptor (CAR) T cell therapy has encountered limited success in solid tumors. The lack of dependable antigens and the immunosuppressive tumor microenvironment (TME) are major challenges. Within the TME, tumor cells along with immuno

Externí odkaz: https://doaj.org/article/eba59695e4f1498cac886149059c76a1

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Å utvikle kommunikativ og kulturelt forankra skrivekompetanse. Ein studie av språklege og tekstlege ressursar i elevtekstar frå dei to første skuleåra

Autor: Randi Solheim, Daroon Yassin Falk, Anne Kathrine Hundal, Synnøve Matre, Astrid Kufaas Morken, Mari Nygård

Publikováno v: Nordisk tidsskrift for utdanning og praksis, Vol 18, Iss 2 (2024)

Denne artikkelen spring ut av eit større intervensjonsprosjekt om tidleg skriveopplæring og er basert på analysar av totalt 541 elevtekstar, samla inn ved slutten av første og andre skuleår. Tekstanalysane er primært empiridrivne, og fleire spr

Externí odkaz: https://doaj.org/article/1edf38bc7c08442f9f3950e3e3d1ce96

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