Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hunain, Khawaja"'
Autor:
Linan Jiang, Hunain Khawaja, Shekha Tahsin, Tanjia A. Clarkson, Cindy K. Miranti, Yitshak Zohar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/ea83606d77b64978ac8fb42784530150
Publikováno v:
Micromachines, Vol 15, Iss 10, p 1195 (2024)
Prostate cancer is a disease in which cells in the prostate, a gland in the male reproductive system below the bladder, grow out of control and, among men, it is the second-most frequently diagnosed cancer (other than skin cancer). In recent years, p
Externí odkaz:
https://doaj.org/article/8da76ab3d0764148be00b51a223b0d4e
Autor:
Linan Jiang, Hunain Khawaja, Shekha Tahsin, Tanjia A. Clarkson, Cindy K. Miranti, Yitshak Zohar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Lack of adequate models significantly hinders advances in prostate cancer treatment, where resistance to androgen-deprivation therapies and bone metastasis remain as major challenges. Current in vitro models fail to faithfully mimic the complex prost
Externí odkaz:
https://doaj.org/article/f8d9c56c0e8442538aa5738540424b5e
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 8304-8315 (2015)
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of double homeobox 4 (DUX4) due to epigenetic changes of the D4Z4 region at chromosome 4q35. Detecting DUX4 is challenging due to its stochastic expression
Externí odkaz:
https://doaj.org/article/04d5f40b3a0b4e6792b6e1b972d3288a
Autor:
Rika Maruyama, Sreetama Sen Chandra, Aiping Zhang, Hunain Khawaja, Peter L. Jones, Kenji Rowel Q. Lim, Quynh Nguyen, Yusuke Echigoya, Takako I. Jones, Yi-Wen Chen, Toshifumi Yokota
Publikováno v:
Proceedings of the National Academy of Sciences. 117:16509-16515
Significance Facioscapulohumeral dystrophy (FSHD) is an inherited disabling muscular disorder caused by misexpression of DUX4 in skeletal muscles. FSHD has variable onset; its infantile form has a more severe disease course. There is no cure for FSHD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36cffd1fa040e10c318e141b5ef20740
https://doi.org/10.1073/pnas.1909649117
https://doi.org/10.1073/pnas.1909649117
Autor:
Maho Shibata, Mamta Gupta, Jing Sun, Kang Le, Mitchell R. Smith, Sanjay B. Maggirwar, Hunain Khawaja
Publikováno v:
Blood Adv
Tumor-associated macrophages (TAMs) are recognized as a hallmark of certain solid cancers and predictors of poor prognosis; however, the functional role of TAMs in lymphoid malignancies, including B-cell lymphoma, has not been well defined. We identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab49baafc941e62f60425a0c36f566be
https://pubmed.ncbi.nlm.nih.gov/34297045
https://pubmed.ncbi.nlm.nih.gov/34297045
Autor:
Kenji Rowel Q, Lim, Rika, Maruyama, Yusuke, Echigoya, Quynh, Nguyen, Aiping, Zhang, Hunain, Khawaja, Sreetama, Sen Chandra, Takako, Jones, Peter, Jones, Yi-Wen, Chen, Toshifumi, Yokota
Publikováno v:
Proc Natl Acad Sci U S A
Facioscapulohumeral muscular dystrophy (FSHD), characterized by progressive muscle weakness and deterioration, is genetically linked to aberrant expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::527bfd34c060b6be6f8e30e8c3f9955e
https://pubmed.ncbi.nlm.nih.gov/32817509
https://pubmed.ncbi.nlm.nih.gov/32817509
Autor:
Geoffrey B. Thompson, Eric B. Schneider, Alireza Najafian, Thomas J. Sebo, Justin A. Bishop, Hunain Khawaja, Helina Somervell, Martha A. Zeiger, Hyun-Seok Kim, Benzon M. Dy, Soonweng Cho, Christopher B. Umbricht, Anna Aronova, Thomas J. Giordano, Patricia Aragon Han, Melissa McAlexander, Roghayeh Fazeli, James R. Eshleman, Thomas J. Fahey, Kenneth W. Witwer, Meredith J. Sorensen, Paul G. Gauger
Publikováno v:
Thyroid. 26:532-542
Studies have demonstrated an association of the BRAF(V600E) mutation and microRNA (miR) expression with aggressive clinicopathologic features in papillary thyroid cancer (PTC). Analysis of BRAF(V600E) mutations with miR expression data may improve pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d27582c53e60c101fe06884e1f1ca1
https://doi.org/10.1089/thy.2015.0378
https://doi.org/10.1089/thy.2015.0378
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 8304-8315 (2015)
Molecules
Volume 20
Issue 5
Pages 8304-8315
Molecules
Volume 20
Issue 5
Pages 8304-8315
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of double homeobox 4 (DUX4) due to epigenetic changes of the D4Z4 region at chromosome 4q35. Detecting DUX4 is challenging due to its stochastic expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc281d91dbea26c5f96508da7e88d4b
http://www.mdpi.com/1420-3049/20/5/8304
http://www.mdpi.com/1420-3049/20/5/8304
Autor:
Vishakha, Sharma, Sachchida Nand, Pandey, Hunain, Khawaja, Kristy J, Brown, Yetrib, Hathout, Yi-Wen, Chen
Publikováno v:
Journal of genetic syndromes & gene therapy
Objective The goal of the study is to identity proteins, which interact with the promoter region of double homeobox protein 4 (DUX4) gene known to be causative for the autosomal dominant disorder Facioscapulohumeral Muscular Dystrophy (FSHD). Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b20a90d96b2dacd42daa4dd9bf15990
https://pubmed.ncbi.nlm.nih.gov/27722032
https://pubmed.ncbi.nlm.nih.gov/27722032