Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Hun-Sik Kim"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Background Psoriasis is an inflammatory skin disease characterized by the hyperproliferative epidermal keratinocytes and significant immune cells infiltration, leading to cytokines production such as IL-1β, TNF-α, IL-23, and IL-17. Recent
Externí odkaz:
https://doaj.org/article/0ede2e5c808b4ab489971aae89420656
Autor:
Woo Seon Choi, Hyung‐Joon Kwon, Eunbi Yi, Haeun Lee, Jung Min Kim, Hyo Jin Park, Eun Ji Choi, Myoung Eun Choi, Young Hoon Sung, Chong Hyun Won, Chang Ohk Sung, Hun Sik Kim
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Distant metastasis, the leading cause of cancer death, is efficiently kept in check by immune surveillance. Studies have uncovered peripheral natural killer (NK) cells as key antimetastatic effectors and their dysregulation during metastasis
Externí odkaz:
https://doaj.org/article/96488816109f40e28e23097a63b02c67
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Natural killer (NK) cells are key effectors in cancer immunosurveillance, eliminating a broad spectrum of cancer cells without major histocompatibility complex (MHC) specificity and graft-versus-host diseases (GvHD) risk. The use of allogeneic NK cel
Externí odkaz:
https://doaj.org/article/ca4661ead14c459fb22af5f3697066f3
Autor:
So Jeong Kim, Jinju Lee, Woo Sun Choi, Hyo Jeong Kim, Mi-Yeon Kim, Sun Chang Kim, Hun Sik Kim
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 6, Pp 695-705 (2021)
Background: Ginsenosides have beneficial effects on several airway inflammatory disorders primarily through glucocorticosteroid-like anti-inflammatory activity. Among inflammatory cells, eosinophils play a major pathogenic role in conferring a risk o
Externí odkaz:
https://doaj.org/article/6543744fec844c06b3f59695006a3d6d
Autor:
Jinju Lee, So Jeong Kim, Go Eun Choi, Eunbi Yi, Hyo Jin Park, Woo Seon Choi, Yong Ju Jang, Hun Sik Kim
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background Eosinophilic inflammation is a hallmark of refractory chronic rhinosinusitis (CRS) and considered a major therapeutic target. Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL
Externí odkaz:
https://doaj.org/article/31cac7d5b18d417198017b3ccb858100
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Natural killer (NK) cells are innate cytotoxic lymphocytes that efficiently eliminate malignant and virus-infected cells without prior activation via the directed and focused release of lytic granule contents for target cell lysis. This cytolytic pro
Externí odkaz:
https://doaj.org/article/eb32828fea69404a98a837c3eb59fdbf
Autor:
Kyoo-Hyung Lee, Suk Ran Yoon, Jeong-Ryeol Gong, Eun-Ji Choi, Hun Sik Kim, Chan-Jeoung Park, Sung-Cheol Yun, Soo-Yeon Park, Sol-Ji Jung, Hanna Kim, Soo Yun Lee, Haiyoung Jung, Jae-Eun Byun, Mirang Kim, Seon-Young Kim, Jeong-Hwan Kim, Je-Hwan Lee, Jung-Hee Lee, Yunsuk Choi, Han-Seung Park, Young-Shin Lee, Young-Ah Kang, Mijin Jeon, Jimin Woo, Hyeran Kang, Seunghyun Baek, Su Mi Kim, Hoon-Min Kim, Kwang-Hyun Cho, Inpyo Choi
Publikováno v:
Leukemia. 37:807-819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b5e9c63e4ffe1667ef33083c5162bdc
https://doi.org/10.1038/s41375-023-01849-5
https://doi.org/10.1038/s41375-023-01849-5
Autor:
Eunsung Jun, Ah Young Song, Ji-Wan Choi, Hyeon Ho Lee, Mi-Yeon Kim, Dae-Hyun Ko, Hyo Jeong Kang, Seong Who Kim, Yenan Bryceson, Song Cheol Kim, Hun Sik Kim
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Natural killer (NK) cells are key effectors in cancer immunosurveillance and can be used as a prognostic biomarker in diverse cancers. Nonetheless, the role of NK cells in pancreatic cancer (PC) remains elusive, given conflicting data on their associ
Externí odkaz:
https://doaj.org/article/b9ee1eb7c01e473393cb8638af7e8ad9
Autor:
Hyung-Joon Kwon, Go-Eun Choi, Sangryeol Ryu, Soon Jae Kwon, Sun Chang Kim, Claire Booth, Kim E. Nichols, Hun Sik Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
NK cell activation requires multiple signals. Here the authors show that while NKG2D, 2B4, or DNAM-1 receptor activation is insufficient to induce cytokine production, these signals synergize by Vav-1-mediated NF-κB multiphosphorylation, and this si
Externí odkaz:
https://doaj.org/article/1e231bdd2f5b49878bcef0ac1df70c15
Tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is cytotoxic to a wide variety of transformed cells, but not to most normal cells, implying potential therapeutic value against advanced cancer. However, signal transduction in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d93f45092fc7668cdfd43a5afe7c5c
https://doi.org/10.1158/0008-5472.c.6493667.v1
https://doi.org/10.1158/0008-5472.c.6493667.v1
