Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hun-Goo Lee"'
Autor:
Carlos Rivera, Hun-Goo Lee, Anna Lappala, Danni Wang, Verónica Noches, Montserrat Olivares-Costa, Marcela Sjöberg-Herrera, Jeannie T. Lee, María Estela Andrés
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The classical neuronal-gene corepressor RCOR1/CoREST is paradoxically enriched in transcriptionally active chromatin. Here the authors show RCOR1 is recruited during promoter-proximal pausing and negatively regulates the nascent-transcript synthesis.
Externí odkaz:
https://doaj.org/article/81f3099598404a4dbd4c6e911f8205fd
Autor:
Ru-Xuan Tsai, Kuo-Chen Fang, Po-Cheng Yang, Yu-Hung Hsieh, I-Tien Chiang, Yunfei Chen, Hun-Goo Lee, Jeannie T Lee, Hsueh-Ping Catherine Chu
Publikováno v:
Nucleic Acids Research. 50:12217-12234
The genome consists of non-B-DNA structures such as G-quadruplexes (G4) that are involved in the regulation of genome stability and transcription. Telomeric-repeat containing RNA (TERRA) is capable of folding into G-quadruplex and interacting with ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2369d4cae42e31b629a341962adb5fa
https://doi.org/10.1093/nar/gkac1114
https://doi.org/10.1093/nar/gkac1114
Autor:
Hun-Goo Lee, Sachiko Imaichi, Elizabeth Kraeutler, Rodrigo Aguilar, Yong-Woo Lee, Steven D. Sheridan, Jeannie T. Lee
Publikováno v:
Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d92255cbd96fddfe9271786e74796d0
https://doi.org/10.1016/j.cell.2023.04.035
https://doi.org/10.1016/j.cell.2023.04.035
Autor:
Yong-Woo Lee, Brian C. Del Rosario, Hyun Jung Oh, Andrea J. Kriz, Myriam Boukhali, Wilhelm Haas, Jeannie T. Lee, Hun-Goo Lee, Eric Aeby
Publikováno v:
Nature Cell Biology. 22:1116-1129
How allelic asymmetry is generated remains a major unsolved problem in epigenetics. Here we model the problem using X-chromosome inactivation by developing "BioRBP", an enzymatic RNA-proteomic method that enables probing of low-abundance interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961779585f03a485a2ab74be6055f894
https://doi.org/10.1038/s41556-020-0558-0
https://doi.org/10.1038/s41556-020-0558-0
Autor:
Barry Kesner, Hyun Jung Oh, Rodrigo Aguilar, Andrea J. Kriz, Hsueh-Ping Chu, Jeannie T. Lee, Hun-Goo Lee
Publikováno v:
Cell. 184(25)
Summary Chromosome loops shift dynamically during development, homeostasis, and disease. CCCTC-binding factor (CTCF) is known to anchor loops and construct 3D genomes, but how anchor sites are selected is not yet understood. Here, we unveil Jpx RNA a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8855e2533c81eebaa307a1dab734c9
https://pubmed.ncbi.nlm.nih.gov/35027738
https://pubmed.ncbi.nlm.nih.gov/35027738
Publikováno v:
Genome Research. 25:1170-1181
Polycomb group (PcG) complexes PRC1 and PRC2 are well known for silencing specific developmental genes. PRC2 is a methyltransferase targeting histone H3K27 and producing H3K27me3, essential for stable silencing. Less well known but quantitatively muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4714ff137849e0ba5893f938069da636
https://doi.org/10.1101/gr.188920.114
https://doi.org/10.1101/gr.188920.114
Autor:
Chunyao Wei, Barry Kesner, Myriam Boukhali, Jeannie T. Lee, Hun-Goo Lee, Hyun Jung Oh, Eric Aeby, Catherine Cifuentes-Rojas, Wilhelm Haas, Hsueh-Ping Chu
Through an integration of genomic and proteomic approaches to advance understanding of long noncoding RNAs, we investigate the function of the telomeric transcript, TERRA. By identifying thousands of TERRA target sites in the mouse genome, we demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60560e62fa69187d63c95e5a95fdac9d
https://europepmc.org/articles/PMC5552367/
https://europepmc.org/articles/PMC5552367/
Publikováno v:
Genomics & Informatics. 7:203-207
The target of rapamycin (TOR) signaling pathway conserved from yeast to human plays critical roles in regulation of eukaryotic cell growth. It has been shown that TOR pathway is involved in several cellular processes, including ribosome biogenesis, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5554611ef1d718aab5e728f9d04b464
https://doi.org/10.5808/gi.2009.7.4.203
https://doi.org/10.5808/gi.2009.7.4.203
Autor:
Soo-Jin Lee, Jeong Ok Kong, Sanghyo Chu, Hyunchul Ryou, Yoonhee Jung, Hun Goo Lee, Jaechul Song
Publikováno v:
Korean Journal of Occupational and Environmental Medicine. 21:337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1dae6609975d110d061ea5481a6929d
https://doi.org/10.35371/kjoem.2009.21.4.337
https://doi.org/10.35371/kjoem.2009.21.4.337
Publikováno v:
Genome Biology
A novel approach for identifying condition-specific regulatory modules in yeast reveals functionally distinct coregulated submodules.
We present an approach for identifying condition-specific regulatory modules by using separate units of gene ex
We present an approach for identifying condition-specific regulatory modules by using separate units of gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780d2ce7f5b5c9dcabd432dfd5390f91
https://doi.org/10.1186/gb-2008-9-1-r2
https://doi.org/10.1186/gb-2008-9-1-r2