Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hun Seok Lee"'
Autor:
Kyoung Song, Nirmal Rajasekaran, Chaithanya Chelakkot, Hun Seok Lee, Seung-Mann Paek, Hobin Yang, Lina Jia, Hee Geon Park, Woo Sung Son, Yu-Jin Kim, Joon-Seok Choi, Hae Min Jeong, Young-Ger Suh, Hwayoung Yun, Young Kee Shin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1060 (2021)
Aerobic glycolysis in cancer cells, also known as the Warburg effect, is an indispensable hallmark of cancer. This metabolic adaptation of cancer cells makes them remarkably different from normal cells; thus, inhibiting aerobic glycolysis is an attra
Externí odkaz:
https://doaj.org/article/a3cd02d1a0b14c19bfd1763848ecc314
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29815-29828 (2015)
Transducer of ERBB2.1 (TOB1) is a tumor-suppressor protein, which functions as a negative regulator of the receptor tyrosine-kinase ERBB2. As most of the other tumor suppressor proteins, TOB1 is inactivated in many human cancers. Homozygous deletion
Externí odkaz:
https://doaj.org/article/1485adeab63840e38a26f3e968c61062
Autor:
Chaithanya Chelakkot, Jiyeon Ryu, Mi Young Kim, Jin-Soo Kim, Dohyeong Kim, Juhyun Hwang, Sung Hoon Park, Seok Bum Ko, Jeong Won Park, Moon Youn Jung, Ryong Nam Kim, Kyoung Song, Yu Jin Kim, Yoon-La Choi, Hun Seok Lee, Young Kee Shin
Publikováno v:
Micromachines, Vol 11, Iss 6, p 560 (2020)
Here, we validated the clinical utility of our previously developed microfluidic device, GenoCTC, which is based on bottom magnetophoresis, for the isolation of circulating tumor cells (CTCs) from patient whole blood. GenoCTC allowed 90% purity, 77%
Externí odkaz:
https://doaj.org/article/bf6f2d2a4e8c4167b093210be92d5ba4
Autor:
Ji-man Kang, Jungmun Suh, Jihyun Kim, Hee-Jin Kim, Yae-jean Kim, Hun Seok Lee, Young Kee Shin, Kangmo Ahn, Sang-Il Lee
Publikováno v:
Korean Journal of Pediatrics, Vol 53, Iss 4, Pp 592-597 (2010)
Hyperimmunoglobulin E syndrome (HIES) is a rare immunodeficiency disease which is characterized by high serum IgE levels, eczema, and recurrent infections. Herein we present the case of a patient with HIES associated with STAT3 gene (stat3) mutation.
Externí odkaz:
https://doaj.org/article/b958ea31a38a4db4950c9b7ab1d6ec70
Autor:
Hun Seok Lee, Cheol-Keun Park, Ensel Oh, Özgür Cem Erkin, Hun Soon Jung, Mi-Hyun Cho, Mi Jeong Kwon, Seoung Wan Chae, Seok-Hyung Kim, Li-Hui Wang, Min-Jeong Park, Su-Yeon Lee, Ho Bin Yang, Lina Jia, Yoon-La Choi, Young Kee Shin
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55522 (2013)
Specificity protein 1 (SP1) is an essential transcription factor that regulates multiple cancer-related genes. Because aberrant expression of SP1 is related to cancer development and progression, we focused on SP1 expression in gastric carcinoma and
Externí odkaz:
https://doaj.org/article/b0a3d4c2bb0c4d8e96ccfd82327f8aad
Publikováno v:
Journal of the Institute of Electronics and Information Engineers. 59:104-112
Autor:
Kyoung Song, Hun Seok Lee, Lina Jia, Chaithanya Chelakkot, Nirmal Rajasekaran, Young Kee Shin
Publikováno v:
Molecules and Cells. 45:413-424
Suppressor of mothers against decapentaplegic homolog (SMAD) 4 is a pluripotent signaling mediator that regulates myriad cellular functions, including cell growth, cell division, angiogenesis, apoptosis, cell invasion, and metastasis, through transfo
Autor:
Young Kee Shin, Yoon-La Choi, Ho Bin Yang, Seoung Wan Chae, Jong-Sun Choi, Özgür Cem Erkin, Li-Hui Wang, Ryong Nam Kim, Sang Gyu Park, Juthika Kundu, Chun Fu Wu, Hun Seok Lee, Lina Jia
Supplementary Figure 1B . AGS, SW480, and HeLa cells were pretreated with control siRNA (lane 1 and 2) or AURKA siRNA (10 nM, lane 3 and 4) for 48 h, and transfected with the plasmid encoding 6Myc-SMAD4 or empty vector. Cells were collected 24 h afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343a528041a6aab087a1ec90a14b3505
https://doi.org/10.1158/1541-7786.22511841.v1
https://doi.org/10.1158/1541-7786.22511841.v1
Autor:
Young Kee Shin, Yoon-La Choi, Ho Bin Yang, Seoung Wan Chae, Jong-Sun Choi, Özgür Cem Erkin, Li-Hui Wang, Ryong Nam Kim, Sang Gyu Park, Juthika Kundu, Chun Fu Wu, Hun Seok Lee, Lina Jia
SMAD4 has been suggested to inhibit the activity of the WNT/β-catenin signaling pathway in cancer. However, the mechanism by which SMAD4 antagonizes WNT/β-catenin signaling in cancer remains largely unknown. Aurora A kinase (AURKA), which is freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac3f6943721b16167b230b877cf788e
https://doi.org/10.1158/1541-7786.c.6540054.v1
https://doi.org/10.1158/1541-7786.c.6540054.v1
Publikováno v:
Journal of Advanced Marine Engineering and Technology. 44:174-180