Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection.

Autor: Webb GM; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Pessoa CT; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., McCullen AJ; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Hwang JM; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Humkey MC; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Thormin-Odum R; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Kukula KA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA., Smedley J; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Fischer M; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Sciurba J; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Bochart RM; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Shriver-Munsch C; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA., Ndhlovu LC; Department of Medicine, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA., Sacha JB; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, USA.; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, Oregon, USA.

Publikováno v: Journal of virology [J Virol] 2024 Jun 13; Vol. 98 (6), pp. e0027324. Date of Electronic Publication: 2024 May 22.