Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Humberto González-Díaz"'
Autor:
Shan He, Karam Nader, Julen Segura Abarrategi, Harbil Bediaga, Deyani Nocedo-Mena, Estefania Ascencio, Gerardo M. Casanola-Martin, Idoia Castellanos-Rubio, Maite Insausti, Bakhtiyor Rasulev, Sonia Arrasate, Humberto González-Díaz
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Neurodegenerative diseases involve progressive neuronal death. Traditional treatments often struggle due to solubility, bioavailability, and crossing the Blood-Brain Barrier (BBB). Nanoparticles (NPs) in biomedical field are garnering growin
Externí odkaz:
https://doaj.org/article/1db442ccc26140babd862363af7d847c
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 15, Iss 1, Pp 535-555 (2024)
Neurodegenerative diseases are characterized by slowly progressing neuronal cell death. Conventional drug treatment strategies often fail because of poor solubility, low bioavailability, and the inability of the drugs to effectively cross the blood
Externí odkaz:
https://doaj.org/article/a43844d82c894783b09d1ad4316364fe
Autor:
Paula Carracedo-Reboredo, Eider Aranzamendi, Shan He, Sonia Arrasate, Cristian R. Munteanu, Carlos Fernandez-Lozano, Nuria Sotomayor, Esther Lete, Humberto González-Díaz
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-24 (2024)
Abstract The enantioselective Brønsted acid-catalyzed α-amidoalkylation reaction is a useful procedure is for the production of new drugs and natural products. In this context, Chiral Phosphoric Acid (CPA) catalysts are versatile catalysts for this
Externí odkaz:
https://doaj.org/article/f057f9940ed64131869e9e1e2d9231a2
Autor:
Estefania Ascencio-Medina, Shan He, Amirreza Daghighi, Kweeni Iduoku, Gerardo M. Casanola-Martin, Sonia Arrasate, Humberto González-Díaz, Bakhtiyor Rasulev
Publikováno v:
Polymers, Vol 16, Iss 19, p 2731 (2024)
This work is devoted to the investigation of dielectric permittivity which is influenced by electronic, ionic, and dipolar polarization mechanisms, contributing to the material’s capacity to store electrical energy. In this study, an extended datas
Externí odkaz:
https://doaj.org/article/836ae715ee7345b3897bc8f950f4050c
Autor:
Maider Baltasar-Marchueta, Leire Llona, Sara M-Alicante, Iratxe Barbolla, Markel Garcia Ibarluzea, Rafael Ramis, Ane Miren Salomon, Brenda Fundora, Ariane Araujo, Arantza Muguruza-Montero, Eider Nuñez, Scarlett Pérez-Olea, Christian Villanueva, Aritz Leonardo, Sonia Arrasate, Nuria Sotomayor, Alvaro Villarroel, Aitor Bergara, Esther Lete, Humberto González-Díaz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116602- (2024)
The development of new molecules for the treatment of calmodulin related cardiovascular or neurodegenerative diseases is an interesting goal. In this work, we introduce a novel strategy with four main steps: (1) chemical synthesis of target molecules
Externí odkaz:
https://doaj.org/article/f435f416ade94dcdb41b2eaf45510160
Autor:
Asier Larrea‐Sebal, Iñaki Sasiain, Shifa Jebari‐Benslaiman, Unai Galicia‐Garcia, Kepa B. Uribe, Asier Benito‐Vicente, Irene Gracia‐Rubio, Harbil Bediaga‐Bañeres, Sonia Arrasate, Ana Cenarro, Fernando Civeira, Humberto González‐Díaz, Cesar Martín
Publikováno v:
Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)
Abstract Familial hypercholesterolemia (FH) is an inherited metabolic disease affecting cholesterol metabolism, with 90% of cases caused by mutations in the LDL receptor gene (LDLR), primarily missense mutations. This study aims to integrate six comm
Externí odkaz:
https://doaj.org/article/91edba494e384699a0634101a006d890
Autor:
Gabriel Mazón-Ortiz, Galo Cerda-Mejía, Eberto Gutiérrez Morales, Karel Diéguez-Santana, Juan M. Ruso, Humberto González-Díaz
Publikováno v:
Diseases, Vol 11, Iss 4, p 153 (2023)
Leishmaniasis is a neglected tropical illness with a wide variety of clinical signs ranging from visceral to cutaneous symptoms, resulting in millions of new cases and thousands of fatalities reported annually. This article provides a bibliometric an
Externí odkaz:
https://doaj.org/article/a384c2073eeb43a8b49a82df7c4fb277
Autor:
Juan Alberto Castillo-Garit, Humberto González-Díaz, Yudith Cañizares-Carmenate, Francisco Torrens, Hai Pham-The, Yoan Martínez-López, Karel Diéguez-Santana
Publikováno v:
Anales de la Academia de Ciencias de Cuba, Vol 1, Iss 11 (2021)
Introducción: La evaluación de los efectos adversos de los contaminantes sobre los ecosistemas y la predicción de propiedades farmacocinéticas de compuestos, son campos de investigación de gran interés. Objetivos: desarrollar modelos computacio
Externí odkaz:
https://doaj.org/article/3f3a5365074140be883501569372247b
Autor:
Alejandro Cabrera-Andrade, Andrés López-Cortés, Gabriela Jaramillo-Koupermann, Humberto González-Díaz, Alejandro Pazos, Cristian R. Munteanu, Yunierkis Pérez-Castillo, Eduardo Tejera
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 409 (2020)
Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year survival rates can reach up to 60–70%, acute complications and late effects of osteosarcoma therapy are two of the limiting factors in treatments. We dev
Externí odkaz:
https://doaj.org/article/321149ad55be4bb8888780e1184ac0ee
Autor:
Enrique Barreiro, Cristian R. Munteanu, Marcos Gestal, Juan Ramón Rabuñal, Alejandro Pazos, Humberto González-Díaz, Julián Dorado
Publikováno v:
Applied Sciences, Vol 10, Iss 4, p 1308 (2020)
Brain Connectome Networks (BCNs) are defined by brain cortex regions (nodes) interacting with others by electrophysiological co-activation (edges). The experimental prediction of new interactions in BCNs represents a difficult task due to the large n
Externí odkaz:
https://doaj.org/article/fb0f5cd254d34107bfdb28664b795af6