Výsledky vyhledávání - "Humberto Carpio"

Synthesis of l,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and homologous pyridine and azepine analogues thereof

Publikováno v: Canadian Journal of Chemistry. 60:2295-2312

Several syntheses of the previously unknown 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and various 5- and 6-substituted derivatives thereof have been devised. Some of these processes have been extended to the heretofore unreported 5,6,7,8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf80eb13ce045ed68fa02624cca5236e
https://doi.org/10.1139/v82-328

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Synthesis of lower chain allenic prostaglandins (1)

Autor: John H Fried, Joseph M. Muchowski, Humberto Carpio

Publikováno v: Prostaglandins. 14:807-811

The synthesis of four lower chain allenic prostaglandin F α analogues IXA-D is described. The allenyl moiety has only occasionally been incorporated into the prostanoid skeleton and in all the examples thus far reported ·(2,3), this functionality i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8755ffcb990a4f5920d146acb411dc5b
https://doi.org/10.1016/0090-6980(77)90297-0

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Synthesis and gastric antisecretory properties of allenic 16-phenoxy-omega-tetranor prostaglandin E analogs

Autor: Gabriel Garay, A.Peter Roszkowski, Angel Guzman, Humberto Carpio, J.A. Mendez, Joseph M. Muchowski, Wren Douglas L, John H Fried, Horn Albert R Van, John A Edwards, Gary F. Cooper

Publikováno v: Prostaglandins. 33:169-180

In order to improve the modest oral activity of PGE 2 as an inhibitor of gastric acid secretion, analogs were prepared and tested orally in histamine-challenged rats. Insertion of a double bond at C-4, resulting in the 4,5-allene analog of PGE 1 , ga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6a776bb77a7a86192270789b23f7cf
https://doi.org/10.1016/0090-6980(87)90004-9

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Synthesis of 2′,2′-difluoro-6,7-dihydro-16-methylenecyclopropa[6,7]progesterone analogues

Autor: Pierre Crabbé, Humberto Carpio, John H Fried

Publikováno v: J. Chem. Soc., Perkin Trans. 1. :227-230

17α-Acetoxy-2′,2′,6β-trifluoro-6β,7β-dihydro-16-methylenecyclopropa[6,7]progesterone (9) and its Δ1-analogue (10) have been synthesised by a ten-step reaction sequence from 3-hydroxy-16-methylpregna-5,16-dien-20-one (1).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5740b439203eb58d6ef44f4f84c0abb
https://doi.org/10.1039/p19730000227

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