Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Humberto, Arzeno"'
Autor:
David M, Goldstein, Michael, Soth, Tobias, Gabriel, Nolan, Dewdney, Andreas, Kuglstatter, Humberto, Arzeno, Jeffrey, Chen, William, Bingenheimer, Stacie A, Dalrymple, James, Dunn, Robert, Farrell, Sandra, Frauchiger, JoAnn, La Fargue, Manjiri, Ghate, Bradford, Graves, Ronald J, Hill, Fujun, Li, Renee, Litman, Brad, Loe, Joel, McIntosh, Daniel, McWeeney, Eva, Papp, Jaehyeon, Park, Harlan F, Reese, Richard T, Roberts, David, Rotstein, Bong, San Pablo, Keshab, Sarma, Martin, Stahl, Man-Ling, Sung, Rebecca T, Suttman, Eric B, Sjogren, Yunchou, Tan, Alejandra, Trejo, Mary, Welch, Paul, Weller, Brian R, Wong, Hasim, Zecic
Publikováno v:
Journal of medicinal chemistry. 54(7)
The development of a new series of p38α inhibitors resulted in the identification of two clinical candidates, one of which was advanced into a phase 2 clinical study for rheumatoid arthritis. The original lead, an lck inhibitor that also potently in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cda31600d6054cc75ed83ea768d5f392
https://pubmed.ncbi.nlm.nih.gov/21375264
https://pubmed.ncbi.nlm.nih.gov/21375264
Autor:
Xavier Lusinchi, Humberto Arzeno, B. Mario Pinto, Reine-Marie Bergé-Lurion, Derek H. R. Barton
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2069-2076
2-Naphthol has been dearomatised by oxidation with 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in the presence of methanol, ethylene glycol, and 2,2-dimethylpropane-1,3-diol to give 1,1-alkoxy-naphthalen-2(1H)-ones in moderate yield. The reaction of 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f9b3a6054c806e7a8d3c5d131746ae
https://doi.org/10.1039/p19840002069
https://doi.org/10.1039/p19840002069