Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Human sequence"'
Autor:
Allen Wang, Joshua Chiou, Olivier B Poirion, Justin Buchanan, Michael J Valdez, Jamie M Verheyden, Xiaomeng Hou, Parul Kudtarkar, Sharvari Narendra, Jacklyn M Newsome, Minzhe Guo, Dina A Faddah, Kai Zhang, Randee E Young, Justinn Barr, Eniko Sajti, Ravi Misra, Heidie Huyck, Lisa Rogers, Cory Poole, Jeffery A Whitsett, Gloria Pryhuber, Yan Xu, Kyle J Gaulton, Sebastian Preissl, Xin Sun, NHLBI LungMap Consortium
Publikováno v:
eLife, Vol 9 (2020)
Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we present single-nucleus accessible chromatin profiles of 90,980 nuclei and matched single-nucleus transcriptomes of 46,500 nuclei in non-diseased lungs from donors of
Externí odkaz:
https://doaj.org/article/a3ede76a7aec424cbe10045fed11ea98
Publikováno v:
The FEBS Journal. 289:4304-4327
Single-domain antibodies (sdAbs), the autonomous variable domains of camelid and shark heavy-chain antibodies, have many desirable properties as components of biologic drugs. However, their sequences may increase the risk of immunogenicity and antidr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c294ad66be5eb47ae797b5cea3d0091
https://doi.org/10.1111/febs.15809
https://doi.org/10.1111/febs.15809
Autor:
Wen-Hsiung Li, Chia-Wei Tai, Jinn-Jy Lin, Yu-Ting Chiou, Tz-Fan Shiu, Chi-An Chen, Yan Yuan Tseng, Tian-Neng Li, Chih-Yao Chang, Maloyjo Joyraj Bhattacharjee, Chia-Yi Chou, Lily Hui-Ching Wang, Paromita Chakraborty
Publikováno v:
Molecular Biology and Evolution
SARS-CoV-2 infects humans through the binding of viral S-protein (spike protein) to human angiotensin I converting enzyme 2 (ACE2). The structure of the ACE2-S-protein complex has been deciphered and we focused on the 27 ACE2 residues that bind to S-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7ec6709df726d8fd9a15d785f795e7
https://doi.org/10.1093/molbev/msab060
https://doi.org/10.1093/molbev/msab060
Autor:
Kevin Y. Yip, Christina Huan Shi
Publikováno v:
Bioinformatics. 36:i625-i633
MotivationIn de novo sequence assembly, a standard pre-processing step is k-mer counting, which computes the number of occurrences of every length-k sub-sequence in the sequencing reads. Sequencing errors can produce many k-mers that do not appear in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b5aa464e8c245dc5e71737f6d7d215
https://doi.org/10.1093/bioinformatics/btaa890
https://doi.org/10.1093/bioinformatics/btaa890
Autor:
Matthew A. Field
Publikováno v:
Immunology and Cell Biology
Sequencing the first human genome in 2003 took 15 years and cost $2.7 billion. Advances in sequencing technologies have since decreased costs to the point where it is now feasible to resequence a whole human genome for $1000 in a single day. These ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1beb57dc03381404414750f35799f18
http://europepmc.org/articles/PMC7891608
http://europepmc.org/articles/PMC7891608
Akademický článek
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Publikováno v:
Cancers
Volume 13
Issue 15
Cancers, Vol 13, Iss 3754, p 3754 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3754, p 3754 (2021)
Simple Summary Peptides expressed on the cell surface can be used to distinguish between diseased and healthy cells and for precision drug targeting. Ideal targets in cancer diagnostics and therapeutic development are the result of altered peptide se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0f7383384433d312dd4d8e60df0a33
Autor:
Voilley, Nicolas, Lingueglia, Eric, Champigny, Guy, Mattei, Marie-Genevieve, Waldmann, Rainer, Lazdunski, Michel, Barbry, Pascal
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1994 Jan 01. 91(1), 247-251.
Externí odkaz:
https://www.jstor.org/stable/2363777
Autor:
Rickard Sandberg, Christoph Ziegenhain
The risks associated with re-identification of human genetic data are severely limiting open data sharing in life sciences. Here, we developed anonymizeBAM, a versatile tool for the anonymization of genetic variant information present in sequence dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0039a5395cce97b774bbd2008399344
https://doi.org/10.1101/2021.01.11.426206
https://doi.org/10.1101/2021.01.11.426206
