Zobrazeno 1 - 10
of 844
pro vyhledávání: '"Human pluripotent stem cell"'
Autor:
Hana Lee, Seunghye Yang, Kyung Jin Lee, Si-Na Kim, Ji-Seon Jeong, Ki Young Kim, Cho-Rok Jung, Sooyeon Jeon, Dayeon Kwon, Sungin Lee, Hanbyeol Lee, Chihye Park, Sun-Ju Ahn, Jongman Yoo, Mi-Young Son
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
To enhance the practical application of intestinal organoids, it is imperative to establish standardized guidelines. This proposed standardization outlines a comprehensive framework to ensure consistency and reliability in the development, characteri
Externí odkaz:
https://doaj.org/article/6f8429ed52b1417d9369cf32af300863
Autor:
Nikola Sekulovski, Jenna C Wettstein, Amber E Carleton, Lauren N Juga, Linnea E Taniguchi, Xiaolong Ma, Sridhar Rao, Jenna K Schmidt, Thaddeus G Golos, Chien-Wei Lin, Kenichiro Taniguchi
Publikováno v:
eLife, Vol 12 (2024)
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants. Previous studies have established that bone morphogenetic protein (BMP) signaling is a ma
Externí odkaz:
https://doaj.org/article/71945dbca40c439f934136cd956265cc
Autor:
Lin Feng, Da Li, Yao Tian, Chengshun Zhao, Yun Sun, Xiaolong Kou, Jun Wu, Liu Wang, Qi Gu, Wei Li, Jie Hao, Baoyang Hu, Yukai Wang
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 458-464 (2024)
Numerous studies have shown that cell replacement therapy can replenish lost cells and rebuild neural circuitry in animal models of Parkinson’s disease. Transplantation of midbrain dopaminergic progenitor cells is a promising treatment for Parkinso
Externí odkaz:
https://doaj.org/article/ed99c5af3e594bedb444190a9a50efcf
Autor:
Qian Liu, Jun Liu, Minmei Guo, Tzu-Cheng Sung, Ting Wang, Tao Yu, Zeyu Tian, Guoping Fan, Wencan Wu, Akon Higuchi
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract Background Retinal degeneration (RD) is a group of disorders on irreversible vision loss. Multiple types of stem cells were used in clinical trials for RD treatment. However, it remains unknown what kinds of stem cells are most effective for
Externí odkaz:
https://doaj.org/article/3a9b2a2f8eca4935a435e775f297ee59
Autor:
Sun-Ku Chung
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 280 (2024)
Bacterial Artificial chromosome (BAC) recombineering is a powerful genetic manipulation tool for the efficient development of recombinant genetic resources. Long homology arms of more than 150 kb composed of BAC constructs not only substantially enha
Externí odkaz:
https://doaj.org/article/92a1e4c3e78c4b9f876e7f62fbcd21e5
Autor:
Cláudia Correia, Jonas Christoffersson, Sandra Tejedor, Saïd El-Haou, Meztli Matadamas-Guzman, Syam Nair, Pierre Dönnes, Gentian Musa, Mattias Rohman, Monika Sundqvist, Rebecca B. Riddle, Bramasta Nugraha, Ioritz Sorzabal Bellido, Markus Johansson, Qing-Dong Wang, Alejandro Hidalgo, Karin Jennbacken, Jane Synnergren, Daniela Später
Publikováno v:
Cells, Vol 13, Iss 16, p 1339 (2024)
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) constitute an appealing tool for drug discovery, disease modeling, and cardiotoxicity screening. However, their physiological immaturity, resembling CMs in the late fetal stage, limits the
Externí odkaz:
https://doaj.org/article/d686b5dc9d3a47b580a621b738a93f64
Autor:
Susan Simorgh, Seyed Ahmad Mousavi, San Kit To, Vincent Pasque, Keimpe Wierda, Tim Vervliet, Meghdad Yeganeh, Paria Pooyan, Yoke Chin Chai, Catherine Verfaillie, Hossein Baharvand
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 1055-1076 (2023)
Human cerebral organoids (COs) are self-organizing three-dimensional (3D) neural structures that provide a human-specific platform to study the cellular and molecular processes that underlie different neurological events. The first step of CO generat
Externí odkaz:
https://doaj.org/article/6912e5eb3a054960b29aa13708ffd2f2
Autor:
Chie Kobori, Ryo Takagi, Ryo Yokomizo, Sakie Yoshihara, Mai Mori, Hiroto Takahashi, Palaksha Kanive Javaregowda, Tomohiko Akiyama, Minoru S. H. Ko, Kazuo Kishi, Akihiro Umezawa
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Background Melanocytes are an essential part of the epidermis, and their regeneration has received much attention because propagation of human adult melanocytes in vitro is too slow for clinical use. Differentiation from human pluripotent st
Externí odkaz:
https://doaj.org/article/fc63b996e0084d08a3e7fc3cc031bf5d
Autor:
Carlotta Ronchi, Camilla Galli, Gabriele Tullii, Camilla Marzuoli, Marta Mazzola, Marco Malferrari, Silvia Crasto, Stefania Rapino, Elisa Di Pasquale, Maria Rosa Antognazza
Publikováno v:
Advanced Science, Vol 11, Iss 3, Pp n/a-n/a (2024)
Abstract Optical stimulation in the red/near infrared range recently gained increasing interest, as a not‐invasive tool to control cardiac cell activity and repair in disease conditions. Translation of this approach to therapy is hampered by scarce
Externí odkaz:
https://doaj.org/article/8bb4ec847c0f4a9d9700bc789c285ac0
Autor:
Elie Frank, Michel Cailleret, Constantin Nelep, Pascal Fragner, Jérome Polentes, Elise Herardot, Lina El Kassar, Karine Giraud-Triboult, Christelle Monville, Karim Ben M’Barek
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in vitro. Such “disease in a dish” models based on human pluripotent stem cells (hPSCs) offer the opportunit
Externí odkaz:
https://doaj.org/article/a0978364e13741ee98c9f4e6a67499fa