Zobrazeno 1 - 10
of 4 386
pro vyhledávání: '"Human mesenchymal"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-32 (2024)
Abstract Diabetes mellitus (DM), a chronic metabolic disease, poses a significant global health challenge, with current treatments often fail to prevent the long-term disease complications. Mesenchymal stem/stromal cells (MSCs) are, adult progenitors
Externí odkaz:
https://doaj.org/article/554fa31f6e9644108a9a6b4d65a35384
Autor:
Mitsuo Oshimura, Toshiaki Tabata, Narumi Uno, Shuta Takata, Genki Hichiwa, Iori Kanazawa, Takeshi Endo, Kazuhisa Honma, Yayan Wang, Kanako Kazuki, Haochen Tu, Yuichi Iida, Satoshi Abe, Yasuhiro Kazuki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Human mesenchymal stem cells (hMSCs) with extended lifespan and differentiation potential that can recapitulate in vivo characteristics could significantly contribute to basic research, drug development, and cell therapy. Specifically, they
Externí odkaz:
https://doaj.org/article/d1875669cd4f4913869ea0d4478c2704
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background The homing of human mesenchymal stem cells (hMSCs) is crucial for their therapeutic efficacy and is characterized by the orchestrated regulation of multiple signaling modules. However, the principal upstream regulators that synchr
Externí odkaz:
https://doaj.org/article/44729d6bdfff408b9c14818622b9b1f8
Publikováno v:
Nano TransMed, Vol 3, Iss , Pp 100058- (2024)
This document is drafted in accordance with GB/T 1.1–2020 ''Standardization work guidelines Part 1: Structure and drafting rules for standardization documents'' to specify the identification methods, inspection rules, label, package,storage, transp
Externí odkaz:
https://doaj.org/article/e335129faf6d4bb0a8826602dfcb34ab
Autor:
Hadi Hajiali, Jane McLaren, Cristina Gonzalez-García, Salah Abdelrazig, Dong-Hyun Kim, Matthew J. Dalby, Manuel Salmerón-Sánchez, Felicity R.A.J. Rose
Publikováno v:
Engineered Regeneration, Vol 5, Iss 2, Pp 255-268 (2024)
Non-healing fractures, a global health concern arising from trauma, osteoporosis, and tumours, can lead to severe disabilities. Adenosine, integral to cellular energy metabolism, gains prominence in bone regeneration via adenosine A2B receptor activa
Externí odkaz:
https://doaj.org/article/6adc2cebbe1349f39c6015cbe6e5f738
Autor:
M Eischen-Loges, Z Tahmasebi Birgani, Y Alaoui Selsouli, L Eijssen, H Rho, M Sthijns, M van Griensven, V LaPointe, P Habibović
Publikováno v:
European Cells & Materials, Vol 47, Pp 170-189 (2024)
Human mesenchymal stem cells (hMSCs) are widely used to model osteogenic differentiation in vitro, yet few studies compare the numerous available protocols. The poor translation between in vitro and in vivo results in bone regeneration highlights the
Externí odkaz:
https://doaj.org/article/f8af60a0733a4c8daf6444b41309d336
Autor:
B. Linju Yen, Li-Tzu Wang, Hsiu-Huang Wang, Chin-Pao Hung, Pei-Ju Hsu, Chia-Chi Chang, Chien-Yu Liao, Huey-Kang Sytwu, Men-Luh Yen
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background The impact of global overconsumption of simple sugars on bone health, which peaks in adolescence/early adulthood and correlates with osteoporosis (OP) and fracture risk decades, is unclear. Mesenchymal stromal/stem cells (MSCs) ar
Externí odkaz:
https://doaj.org/article/d5b10c70dac547cb8fd207e96e60940c
Publikováno v:
Mechanobiology in Medicine, Vol 3, Iss 1, Pp 100111- (2025)
Human mesenchymal stem cells (hMSCs) have immense wound healing potential due to their immunomodulatory behavior. To control this behavior and reduce heterogeneity, researchers look to biomaterials, as matrix stiffness and viscoelasticity have been s
Externí odkaz:
https://doaj.org/article/d48c59863c854c5dad886e919208ffee
Autor:
Mariani Devi, Neni Susilaningsih, Parish Budiono, Nani Maharani, Erik Prabowo, Ignatius Riwanto
Publikováno v:
Journal of Advanced Biotechnology and Experimental Therapeutics, Vol 7, Iss 2, Pp 451-459 (2024)
Globally, the annual mortality rate due to liver cirrhosis is 2.2%, which ranks 12th as the cause of death in the United States. Human mesenchymal stem cell secretome (Hu-MSC-S) is known to reduce liver injury and inflammation. Thus, the present stud
Externí odkaz:
https://doaj.org/article/0259665ba8e545ee85ace0f279fe02c9
Autor:
Huiyuan Peng, Weihua Guo, Jinsong Wang, Weili Xia, Yu Xiong, Wenhua Xu, Weibo Dai, Feng Zheng
Publikováno v:
Alexandria Engineering Journal, Vol 91, Iss , Pp 648-657 (2024)
Addressing the devastating and often irreversible effects of stroke necessitates innovative therapeutic strategies that go beyond the limitations of current treatments. This study heralds a promising interdisciplinary approach by employing LAP/PDA co
Externí odkaz:
https://doaj.org/article/b56885302744448abfa1fe0a5e962ae9