Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Human liver chimeric mice"'
Autor:
Katja Giersch, Paulina Perez-Gonzalez, Lennart Hendricks, Nora Goldmann, Jonathan Kolbe, Lennart Hermanussen, Jan-Hendrick Bockmann, Tassilo Volz, Annika Volmari, Lena Allweiss, Joerg Petersen, Dieter Glebe, Marc Lütgehetmann, Maura Dandri
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100673- (2023)
Background & Aims: Pegylated interferon alpha (pegIFNα) is commonly used for the treatment of people infected with HDV. However, its mode of action in HDV-infected cells remains elusive and only a minority of people respond to pegIFNα therapy. Here
Externí odkaz:
https://doaj.org/article/01d54f34c762458ab95d9601864425ef
Autor:
Dandri M, Petersen J
Publikováno v:
Infection and Drug Resistance, Vol Volume 13, Pp 3873-3886 (2020)
Maura Dandri,1,2 Joerg Petersen3 1Department of Internal Medicine, University Medical Center Hamburg – Eppendorf, Hamburg, Germany; 2German Center for Infection Research (DZIF), Hamburg-Luebeck-Borstel-Riems Site, Germany; 3Institute for Interdisci
Externí odkaz:
https://doaj.org/article/259f5f2c1f574943b216aa647de216bb
Autor:
Laura Collignon, Lieven Verhoye, Renate Hakze-Van der Honing, Wim H. M. Van der Poel, Philip Meuleman
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The hepatitis E virus (HEV) is responsible for 20 million infections worldwide per year. Although, HEV infection is mostly self-limiting, immunocompromised individuals may evolve toward chronicity. The lack of an efficient small animal model has hamp
Externí odkaz:
https://doaj.org/article/9c130d2b8742448ab5562abfc97517b5
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Long V. Pham, Rodrigo Velázquez-Moctezuma, Ulrik Fahnøe, Laura Collignon, Priyanka Bajpai, Christina Sølund, Nina Weis, Kenn Holmbeck, Jannick Prentoe, Jens Bukh
Publikováno v:
Viruses, Vol 14, Iss 11, p 2527 (2022)
Hepatitis C virus (HCV) genotype 4 is highly prevalent in the Middle East and parts of Africa. Subtype 4d has recently spread among high-risk groups in Europe. However, 4d infectious culture systems are not available, hampering studies of drugs, as w
Externí odkaz:
https://doaj.org/article/a1d9cda048864f47943b04977b05abfb
Autor:
Katja Giersch, Lennart Hermanussen, Tassilo Volz, Annika Volmari, Lena Allweiss, Camille Sureau, John Casey, Jiabin Huang, Nicole Fischer, Marc Lütgehetmann, Maura Dandri
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
BackgroundHepatitis D Virus (HDV) is classified into eight genotypes with distinct clinical outcomes. Despite the maintenance of highly conserved functional motifs, it is unknown whether sequence divergence between genotypes, such as HDV-1 and HDV-3,
Externí odkaz:
https://doaj.org/article/6217e92b09c84254849aad0d31065465
Autor:
Christine Y.L. Tham, Janine Kah, Anthony T. Tan, Tassilo Volz, Adeline Chia, Katja Giersch, Yvonne Ladiges, Alessandro Loglio, Marta Borghi, Camille Sureau, Pietro Lampertico, Marc Lütgehetmann, Maura Dandri, Antonio Bertoletti
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 4, Pp 100060- (2020)
Summary: Hepatitis delta virus (HDV) requires hepatitis B virus (HBV) to complete its infection cycle and causes severe hepatitis, with limited therapeutic options. To determine the prospect of T cell therapy in HBV/HDV co-infection, we study the imp
Externí odkaz:
https://doaj.org/article/6d4ddfe9419f438f9c91e9142a2b1cb6
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Persistent hepatitis B virus (HBV) infection causes liver cirrhosis and hepatocellular carcinoma and constitutes a major worldwide health problem. Currently, anti-HBV drugs are limited to peginterferon and nucleos(t)ide analogs, w
Externí odkaz:
https://doaj.org/article/f5c5985b85be4820aa3441930d118d41
Autor:
Keishi Kisoh, Go Sugahara, Yuko Ogawa, Suzue Furukawa, Yuji Ishida, Takeshi Okanoue, Michinori Kohara, Chise Tateno
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1647 (2021)
Nonalcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) is the most common liver disorder in developed countries. Although many new therapeutics for NASH are present in the drug development pipeline, there are still no approved drugs. One of th
Externí odkaz:
https://doaj.org/article/65006a448cac4620b052520da4f8a0a4
Autor:
Jiayin Yang, Yu Wang, Ting Zhou, Lai-Yung Wong, Xiao-Yu Tian, Xueyu Hong, Wing-Hon Lai, Ka-Wing Au, Rui Wei, Yuqing Liu, Lai-Hung Cheng, Guichan Liang, Zhijian Huang, Wenxia Fan, Ping Zhao, Xiwei Wang, David P. Ibañez, Zhiwei Luo, Yingying Li, Xiaofen Zhong, Shuhan Chen, Dongye Wang, Li Li, Liangxue Lai, Baoming Qin, Xichen Bao, Andrew P. Hutchins, Chung-Wah Siu, Yu Huang, Miguel A. Esteban, Hung-Fat Tse
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 605-618 (2017)
Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C) in blood and carries an increased risk of early-onset cardiovascular disease. A caveat for exploration of new therapies for FH is the lack of adequate
Externí odkaz:
https://doaj.org/article/c8b746bcc4d14c1ea35c0ee1de8c99b8