Zobrazeno 1 - 10
of 5 029
pro vyhledávání: '"Human induced pluripotent stem cells"'
Publikováno v:
口腔疾病防治, Vol 32, Iss 10, Pp 805-813 (2024)
Bone diseases, such as osteoporosis and osteoarthritis, have emerged as pressing public health concerns requiring immediate attention and resolution. Cellular therapy and tissue engineering techniques are among the most promising therapeutic approach
Externí odkaz:
https://doaj.org/article/927c16d9b3a74498982bdb5396efa05a
Autor:
Andrea Balogh, Mária Bódi-Jakus, Vivien Réka Karl, Tamás Bellák, Balázs Széky, János Farkas, Federica Lamberto, David Novak, Anita Fehér, Melinda Zana, András Dinnyés
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract In the present study, we aimed to establish and characterize a mature cortical spheroid model system for Kleefstra syndrome (KS) using patient-derived iPSC. We identified key differences in the growth behavior of KS spheroids determined by r
Externí odkaz:
https://doaj.org/article/06195f2e86214261b189325dc26c9d8d
Autor:
Conglin Wang, Fangyuan Cheng, Zhaoli Han, Bo Yan, Pan Liao, Zhenyu Yin, Xintong Ge, Dai Li, Rongrong Zhong, Qiang Liu, Fanglian Chen, Ping Lei
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 2, Pp 518-532 (2025)
Cerebral edema caused by blood–brain barrier injury after intracerebral hemorrhage is an important factor leading to poor prognosis. Human-induced pluripotent stem cell–derived neural stem cell exosomes (hiPSC–NSC–Exos) have shown potential f
Externí odkaz:
https://doaj.org/article/7f5b8dcf3a774d90ab1d785e21426e40
Autor:
Mohammadjafar Hashemi, Ferdous B. Finklea, Hanna Hammons, Yuan Tian, Nathan Young, Emma Kim, Caroline Halloin, Wiebke Triebert, Robert Zweigerdt, Amit Kumar Mitra, Elizabeth A. Lipke
Publikováno v:
Bioactive Materials, Vol 43, Iss , Pp 423-440 (2025)
A reliable suspension-based platform for scaling engineered cardiac tissue (ECT) production from human induced pluripotent stem cells (hiPSCs) is crucial for regenerative therapies. Here, we compared the production and functionality of ECTs formed us
Externí odkaz:
https://doaj.org/article/52fce42f65614dd89c7a6701b6a9ef7b
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 922-931 (2024)
Introduction: Preparing a uniform cell population in high–density seeding of adherent human induced pluripotent stem cells (hiPSC) requires stable culture conditions and consistent culture operation. In this study, we evaluated cell distribution pa
Externí odkaz:
https://doaj.org/article/0370f517a1a8460b98f072575d4a770f
Autor:
Divya Sridharan, Julie A. Dougherty, Uzair Ahmed, Shridhar K. Sanghvi, Syed Baseeruddin Alvi, Ki Ho Park, Helena Islam, Sue E. Knoblaugh, Harpreet Singh, Elizabeth D. Kirby, Mahmood Khan
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Human induced pluripotent stem cells (hiPSCs) and their differentiated cell types have a great potential for tissue repair and regeneration. While the primary focus of using hiPSCs has historically been to regenerate damaged tissu
Externí odkaz:
https://doaj.org/article/3817c12ff63f4441b96167eaf8169674
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 301-316 (2024)
Natural killer (NK) cells are cytotoxic immune cells that can eliminate target cells without prior stimulation. Human induced pluripotent stem cells (iPSCs) provide a robust source of NK cells for safe and effective cell-based immunotherapy against a
Externí odkaz:
https://doaj.org/article/60e23d6bd9644ea891c510a9c136de24
Autor:
Noemi Elia, Federica Prinelli, Valeria Peli, Silvia Conti, Mario Barilani, Cecilia Mei, Silvana Castaldi, Lorenza Lazzari
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionHuman induced pluripotent stem cells (hiPSCs), derived from reprogrammed adult somatic cells, hold significant promise for disease modelling, personalized medicine, drug discovery, and regenerative therapies. Public awareness and understa
Externí odkaz:
https://doaj.org/article/397714fe223f495cb8fe58b742fc15f2
Autor:
Banaja P. Dash, Axel Freischmidt, Anika M. Helferich, Albert C. Ludolph, Peter M Andersen, Jochen H. Weishaupt, Andreas Hermann
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (MNs) present in the spinal cord, brain stem and motor cortex. Death in most patients usually occurs within 2–4 years after sy
Externí odkaz:
https://doaj.org/article/77b180617b084d8f80eee9573f507f7c
Autor:
Janice Raabe, Ilka Wittig, Patrick Laurette, Konstantina Stathopoulou, Theresa Brand, Thomas Schulze, Birgit Klampe, Ellen Orthey, Alfredo Cabrera-Orefice, Jana Meisterknecht, Ellen Thiemann, Sandra D. Laufer, Aya Shibamiya, Marina Reinsch, Sigrid Fuchs, Jennifer Kaiser, Jiaqi Yang, Simonida Zehr, Kinga M. Wrona, Kristina Lorenz, Robert Lukowski, Arne Hansen, Ralf Gilsbach, Ralf P. Brandes, Bärbel M. Ulmer, Thomas Eschenhagen, Friederike Cuello
Publikováno v:
Redox Biology, Vol 77, Iss , Pp 103352- (2024)
Human induced pluripotent stem cells (hiPSCs) are an invaluable tool to study molecular mechanisms on a human background. Culturing stem cells at an oxygen level different from their microenvironmental niche impacts their viability. To understand thi
Externí odkaz:
https://doaj.org/article/d9714c52734f4b87ab939aa73d9d8316