Výsledky vyhledávání - "Human induced pluripotent stem cell derived cardiomyocytes"

Akademický článek

Esophageal Cancer-Related Gene-4 Contributes to Lipopolysaccharide-Induced Ion Channel Dysfunction in hiPSC-Derived Cardiomyocytes

Autor: Xu Q, Zhang X, Hao M, Dang X, Cyganek L, Akin I, Tang D, Liao B, Zhou X, Lan H

Publikováno v: Journal of Inflammation Research, Vol Volume 17, Pp 10183-10197 (2024)

Qiang Xu,1,2,* Xiangjie Zhang,3,* Maolin Hao,3,* Xitong Dang,3 QianQian Xu,3 Lukas Cyganek,4,5 Ibrahim Akin,2,6 Dan Tang,7 Bin Liao,8 Xiaobo Zhou,2,3,6 Huan Lan3 1School of Basic Medical Science, Southwest Medical University, Luzhou, Peop

Externí odkaz: https://doaj.org/article/9f9e309802c44f3283fca5acb0e4d221

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Akademický článek

Modified mRNA-based gene editing reveals sarcomere-based regulation of gene expression in human induced-pluripotent stem cell-derived cardiomyocytes

Autor: Huang, Yuqing ^{a, 1}, Zhang, Yueyang ^{b, 1}, Wang, Ze ^b, Miao, Lei ^{c, d}, Tan, Pingping ^a, Guan, Yuting ^a, Ran, Yuqing ^a, Feng, Xing ^a, Wang, Yijia ^a, Guo, Yuxuan ^{b, e, f, ⁎}, Guo, Xiaoling ^{a, ⁎⁎}

Publikováno v: In International Immunopharmacology 25 December 2024 143 Part 2

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Akademický článek

Adipocyte-Mediated Electrophysiological Remodeling of PKP-2 Mutant Human Pluripotent Stem Cell-Derived Cardiomyocytes

Autor: Justin Morrissette-McAlmon, Christianne J. Chua, Alexander Arking, Stanley Chun Ming Wu, Roald Teuben, Elaine Zhelan Chen, Leslie Tung, Kenneth R. Boheler

Publikováno v: Biomedicines, Vol 12, Iss 11, p 2601 (2024)

Background: Arrhythmogenic cardiomyopathy (ACM) is a genetic disorder responsible for nearly a quarter of sports-related sudden cardiac deaths. ACM cases caused by mutations in desmosome proteins lead to right ventricular enlargement, the loss of car

Externí odkaz: https://doaj.org/article/678dfc6c65cb4ef084c473df1c6fcf64

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Akademický článek

Physiological stress improves stem cell modeling of dystrophic cardiomyopathy

Autor: Dominic E. Fullenkamp, Alexander B. Willis, Jodi L. Curtin, Ansel P. Amaral, Kyle T. Dittloff, Sloane I. Harris, Ivana A. Chychula, Cory W. Holgren, Paul W. Burridge, Brenda Russell, Alexis R. Demonbreun, Elizabeth M. McNally

Publikováno v: Disease Models & Mechanisms, Vol 17, Iss 6 (2024)

Externí odkaz: https://doaj.org/article/b52a5eadd7514af8ba2316e6c7190c6b

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Akademický článek

Pulsed electric field performance calculator tool based on an in vitro human cardiac model

Autor: Maura Casciola, Abouzar Kaboudian, Tromondae K. Feaster, Akshay Narkar, Ksenia Blinova

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

IntroductionPulsed Field Ablation (PFA) is a novel non-thermal method for cardiac ablation, relying on irreversible electroporation induced by high-energy pulsed electric fields (PEFs) to create localized lesions in the heart atria. A significant cha

Externí odkaz: https://doaj.org/article/d2cea56cd73e427fbb2feaf73538409e

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Akademický článek

Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin

Autor: Yuki Tanaka, Shin Kadota, Jian Zhao, Hideki Kobayashi, Satomi Okano, Masaki Izumi, Yusuke Honda, Hajime Ichimura, Naoko Shiba, Takeshi Uemura, Yuko Wada, Shinichiro Chuma, Tsutomu Nakada, Shugo Tohyama, Keiichi Fukuda, Mitsuhiko Yamada, Tatsuichiro Seto, Koichiro Kuwahara, Yuji Shiba

Publikováno v: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)

Abstract Background Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can be used to treat heart diseases; however, the optimal maturity of hiPSC-CMs for effective regenerative medicine remains unclear. We aimed to investigate th

Externí odkaz: https://doaj.org/article/b753b6a2aa8c41179aa9cf4247289cee

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Akademický článek

Modeling incomplete penetrance in arrhythmogenic cardiomyopathy by human induced pluripotent stem cell derived cardiomyocytes

Autor: Marzia De Bortoli, Viviana Meraviglia, Katarina Mackova, Laura S. Frommelt, Eva König, Johannes Rainer, Chiara Volani, Patrizia Benzoni, Maja Schlittler, Giada Cattelan, Benedetta M. Motta, Claudia Volpato, Werner Rauhe, Andrea Barbuti, Serena Zacchigna, Peter P. Pramstaller, Alessandra Rossini

Publikováno v: Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1759-1773 (2023)

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are commonly used to model arrhythmogenic cardiomyopathy (ACM), a heritable cardiac disease characterized by severe ventricular arrhythmias, fibrofatty myocardial replacement and

Externí odkaz: https://doaj.org/article/2220b6b3a2c54765af91e30f1c2ec426

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In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging

Autor: Yukihiro Saito, Naoko Nose, Toshihiro Iida, Kaoru Akazawa, Takayuki Kanno, Yuki Fujimoto, Takanori Sasaki, Masaru Akehi, Takahiro Higuchi, Satoshi Akagi, Masashi Yoshida, Toru Miyoshi, Hiroshi Ito, Kazufumi Nakamura

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

IntroductionTransplantation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is a promising treatment for heart failure. Information on long-term cell engraftment after transplantation is clinically important. However, clinica

Externí odkaz: https://doaj.org/article/4b50470f16fc41e0995e29db4a77eded

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