Zobrazeno 1 - 10
of 760
pro vyhledávání: '"Human epidermal growth factor receptor 2 (HER2)"'
Autor:
Ingrid Karmane Sumou, Cheng Vai Hui
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Fam-trastuzumab deruxtecan (T-DXd) has demonstrated substantial antitumor activity and durable responses in patients with human epidermal growth factor receptor 2 positive (HER2+) metastatic breast cancer. We report here the treatment outcomes of T-D
Externí odkaz:
https://doaj.org/article/8b714701705f4e42adfff2c10010d807
Autor:
Minsun Jung, Seung Geun Song, Soo Ick Cho, Sangwon Shin, Taebum Lee, Wonkyung Jung, Hajin Lee, Jiyoung Park, Sanghoon Song, Gahee Park, Heon Song, Seonwook Park, Jinhee Lee, Mingu Kang, Jongchan Park, Sergio Pereira, Donggeun Yoo, Keunhyung Chung, Siraj M. Ali, So-Woon Kim
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Accurate classification of breast cancer molecular subtypes is crucial in determining treatment strategies and predicting clinical outcomes. This classification largely depends on the assessment of human epidermal growth factor re
Externí odkaz:
https://doaj.org/article/da6c5719a5244deb836c57c329007535
Autor:
Elias Obeid, Rohan C. Parikh, Elizabeth Esterberg, Bhakti Arondekar, Abigail Hitchens, Lillian Shahied Arruda, Alexander Niyazov, Kristen Whitaker
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
AimTo examine clinical characteristics, real-world treatment patterns, and health outcomes among patients with germline BRCA1/2-mutated, human epidermal growth factor receptor 2 (HER2)–negative advanced breast cancer (ABC).MethodsA retrospective an
Externí odkaz:
https://doaj.org/article/87cee8aa415a4c878d1bef57e7b50c16
Autor:
Kåre Nielsen, Michael Sode, Maj-Britt Jensen, Tobias Berg, Ann Knoop, Bent Ejlertsen, Anne-Vibeke Lænkholm
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Considering the recent advancements in the treatment of breast cancer with low expression of human epidermal growth factor receptor 2 (HER2), we aimed to examine inter-laboratory variability in the assessment of HER2-low breast ca
Externí odkaz:
https://doaj.org/article/583bda67c17f4c7397476b126b81c79d
Autor:
Zaka Ur Rehman, Mohammad Faizal Ahmad Fauzi, Wan Siti Halimatul Munirah Wan Ahmad, Fazly Salleh Abas, Phaik Leng Cheah, Seow Fan Chiew, Lai-Meng Looi
Publikováno v:
Diagnostics, Vol 14, Iss 18, p 2089 (2024)
Recent advancements in medical imaging have greatly enhanced the application of computational techniques in digital pathology, particularly for the classification of breast cancer using in situ hybridization (ISH) imaging. HER2 amplification, a key p
Externí odkaz:
https://doaj.org/article/0a4c1469a8004f3984abe2ceccc64086
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
ObjectivePyrotinib and pertuzumab are effective treatment options for HER2-positive metastatic breast cancer (HER2+ MBC). Our study was to directly compare the efficacy and safety of pyrotinib plus trastuzumab (PyroH) and pertuzumab plus trastuzumab
Externí odkaz:
https://doaj.org/article/8498e7ce732f4014bdb8a05c40ff20e6
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4579-4589 (2023)
Abstract Near‐infrared photoimmunotherapy (NIR‐PIT) is a novel form of cancer treatment using conjugates of antibody against overexpressed antigens in cancers and photoabsorber IRDye700DX. HER2 is overexpressed in various cancers, for which molec
Externí odkaz:
https://doaj.org/article/2e5310775903472a9181269fdcbddf10
Autor:
Kana Fujimoto, Satomi Watanabe, Yuto Yasuda, Emi Date, Yasuhiro Kawabata, Hiroaki Kanemura, Takayuki Takahama, Kimio Yonesaka, Norishige Iizuka, Ken‐ichi Takahashi, Osamu Kawakami, Tomohiro Ozaki, Kazuhiko Nakagawa
Publikováno v:
Thoracic Cancer, Vol 14, Iss 2, Pp 214-217 (2023)
Abstract High‐grade fetal lung adenocarcinoma (H‐FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56‐year‐old ma
Externí odkaz:
https://doaj.org/article/3c35c62de9b54473a554522542d5f956
Publikováno v:
Cancer Medicine, Vol 11, Iss 24, Pp 4954-4965 (2022)
Abstract Background Accurate diagnostic biomarker testing is crucial to treatment decisions in breast cancer. Biomarker testing is performed on core needle biopsies (CNB) and is often repeated in the surgical specimen (SS) after resection. As differe
Externí odkaz:
https://doaj.org/article/e731e81538ff49b092098380493e0cdd
Autor:
Hebatalla Elkassas, Maha Hussein Helal, Hisham S. Wahba Mikhael, Rana Khaled, Ahmed Farahat, Samar M. El-Maadawy
Publikováno v:
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 53, Iss 1, Pp 1-10 (2022)
Abstract Background Breast cancer is the leading cause of cancer-related mortality in women. Human epidermal growth factor receptor 2 (HER2) overexpression is seen in 20 out of 100 invasive breast cancers. Among HER2+ patients, two distinct hormone r
Externí odkaz:
https://doaj.org/article/616ffad128c7477ca2082bd7f1945fe5