Zobrazeno 1 - 10 of 52 pro vyhledávání: '"Human endogenous retrovirus W"'
1
Akademický článek
Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis
Autor: Ute-Christiane Meier, Richard Christopher Cipian, Abbas Karimi, Ranjan Ramasamy, Jaap Michiel Middeldorp
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating
Externí odkaz: https://doaj.org/article/db82f7b4d610457395c364e5abdf8e4a
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2
Akademický článek
Differential Expression of HERV-W in Peripheral Blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups
Autor: Rachael Tarlinton, Belinda Wang, Elena Morandi, Bruno Gran, Timur Khaiboullin, Ekatarina Martynova, Albert Rizvanov, Svetlana Khaiboullina
Publikováno v: Frontiers in Pharmacology, Vol 10 (2020)
Overexpression of the Human endogenous retrovirus W (HERV-W) group of inherited retroviruses has been consistently linked with Multiple Sclerosis (MS). However most of the studies on this link have focused on European genetic groups with a very high
Externí odkaz: https://doaj.org/article/8f67c5bb55784802b162c3e8ac372d11
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3
Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis
Autor: Jaap M. Middeldorp, Richard Christopher Cipian, Ute-Christiane Meier, Abbas Karimi, Ranjan Ramasamy
Publikováno v: Frontiers in Immunology, 12:757302
Meier, U-C, Cipian, R C, Karimi, A, Ramasamy, R & Middeldorp, J M 2021, ' Cumulative Roles for Epstein-Barr Virus, Human Endogenous Retroviruses, and Human Herpes Virus-6 in Driving an Inflammatory Cascade Underlying MS Pathogenesis ', Frontiers in Immunology, vol. 12, 757302 . https://doi.org/10.3389/fimmu.2021.757302
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Roles for viral infections and aberrant immune responses in driving localized neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of intense research. Epstein-Barr virus (EBV), as a persistent and frequently reactivating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f40dd1787a0b4861f1a04bd80f87a9
https://research.vumc.nl/en/publications/fd254190-bd3f-42b1-966a-a87b953fdb64
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4
Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients
Autor: Branka Horvat, Sergio Bernardini, Sandro Grelli, Vita Petrone, Massimo Andreoni, Antonella Minutolo, Vincenzo Malagnino, Hervé Perron, Paolo Di Francesco, Loredana Sarmati, Marco Iannetta, Benjamin Charvet, Enrico Garaci, Emanuela Balestrieri, Paola Sinibaldi Vallebona, Marta Zordan, Pietro Vitale, Claudia Matteucci, Marialaura Fanelli
Publikováno v: EBioMedicine, Vol 66, Iss, Pp 103341-(2021)
EBioMedicine
Background Despite an impressive effort in clinical research, no standard therapeutic approach for coronavirus disease 2019 (COVID-19) patients has been established, highlighting the need to identify early biomarkers for predicting disease progressio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3720ba21561b6d50d5dbd6bb75aeb9a7
https://pubmed.ncbi.nlm.nih.gov/33867312
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5
Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study
Autor: Frederik Barkhof, François Curtin, David Leppert, Patrick Küry, Ferran Prados, Jonathan Stutters, Gabrielle Kornmann, David G. MacManus, Thomas Rückle, Krzysztof Selmaj, Estelle Lambert, Hans-Peter Hartung, Bruce A.C. Cree, Hans Martin Schneble, Robert Glanzman, David Warne, Tobias Derfuss, Maria Pia Sormani, Bénédicte Buffet, Hervé Porchet, David Kremer
Publikováno v: Hartung, H-P, Derfuss, T, Cree, B A C, Sormani, M P, Selmaj, K, Stutters, J, Prados, F, MacManus, D, Schneble, H-M, Lambert, E, Porchet, H, Glanzman, R, Warne, D, Curtin, F, Kornmann, G, Buffet, B N, Kremer, D, Küry, P, Leppert, D, Rückle, T & Barkhof, F 2021, ' Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study ', Multiple Sclerosis Journal . https://doi.org/10.1177/13524585211024997
O2, repositorio institucional de la UOC
Universitat Oberta de Catalunya (UOC)
Multiple Sclerosis Journal. SAGE Publications Ltd
Background: The envelope protein of human endogenous retrovirus W (HERV-W-Env) is expressed by macrophages and microglia, mediating axonal damage in chronic active MS lesions. Objective and Methods: This phase 2, double-blind, 48-week trial in relaps
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe63a345ca2dbfab0571857b780a4da
https://research.vumc.nl/en/publications/eeac3db0-5b8c-4065-8995-328a18e886d9
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6
The Association between Plasma ERVWE1 Concentrations and Affective Symptoms during Pregnancy: Is This a Friendly Alien?
Autor: Jennifer L. Barkin, Cecilia Maria Esposito, Valentina Bollati, Marta Serati, Massimiliano Buoli, Silvia Grassi
Publikováno v: International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 9217, p 9217 (2020)
Human endogenous retroviruses (HERVs) comprise 8% of the human genome, and HERV DNA was reported to be essential in human embryonic development. Specifically, HERV-W encodes a protein, syncytin-1, alternatively known as ERVWE1 (Human Endogenous Retro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16089cd768b48c71be7052d9488617ab
https://pubmed.ncbi.nlm.nih.gov/33317172
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7
Akademický článek
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8
Effects of metal-rich particulate matter exposure on exogenous and endogenous viral sequence methylation in healthy steel-workers
Autor: Serena Delbue, Matteo Bonzini, Simona Iodice, Valentina Bollati, Jacopo Mariani, Roberta Mercorio, Laura Angelici, Angela Cecilia Pesatori, Pietro Apostoli
Publikováno v: Environmental Research. 159:452-457
Background Inhaled particles have been shown to produce systemic changes in DNA methylation. Global hypomethylation has been associated to viral sequence reactivation, possibly linked to the activation of pro-inflammatory pathways occurring after exp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5378b649f06444beb25db6536a64c3b
https://doi.org/10.1016/j.envres.2017.08.042
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9
Differential Expression of HERV-W in Peripheral Blood in Multiple Sclerosis and Healthy Patients in Two Different Ethnic Groups
Autor: E. V. Martynova, Elena Morandi, Timur I. Khaiboullin, Belinda Wang, Albert A. Rizvanov, Svetlana F. Khaiboullina, Rachael E. Tarlinton, Bruno Gran
Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2020)
Overexpression of the Human endogenous retrovirus W (HERV-W) group of inherited retroviruses has been consistently linked with Multiple Sclerosis (MS). However most of the studies on this link have focused on European genetic groups with a very high
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d171d68ec190f17cbfc7d4869a9a477
https://pubmed.ncbi.nlm.nih.gov/32076404
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10
Akademický článek
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